Results 151 to 160 of about 33,509 (296)

Binding Interactions with the Complementary Subunit of Nicotinic Receptors [PDF]

, 2013
The agonist-binding site of nicotinic acetylcholine receptors (nAChRs) spans an interface between two subunits of the pentameric receptor. The principal component of this binding site is contributed by an α subunit, and it binds the cationic moiety of ...
Blum, Angela P., Dougherty, Dennis A., German, Laurel A., Lester, Henry A., Van Arnam, Ethan B.   +4 more
core  

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Preclinical Pharmacology of ABT‐594: A Nicotinic Acetylcholine Receptor Agonist for the Treatment of Pain [PDF]

, 2000
Michael D. Meyer, David J. Anderson, Jeffrey E. Campbell, Sherry Carroll, Kennan C. Marsh, A. David Rodrigues, Michael Decker   +6 more
openalex   +1 more source

Autoantibodies and Inflammation in Schizophrenia

Psychiatry and Clinical Neurosciences, EarlyView.
The potential role of autoantibodies in the etiology of schizophrenia is a key research focus because growing evidence suggests an association between immune dysfunction and psychotic disorders. This hypothesis is supported by findings indicating immune‐related abnormalities in patients with schizophrenia, including chronic inflammation and genetic ...
Hiroki Shiwaku
wiley   +1 more source

Contributions of Torpedo Nicotinic Acetylcholine Receptor γTrp-55 and δTrp-57 to Agonist and Competitive Antagonist Function [PDF]

, 2001
Yu Xie, Jonathan B. Cohen
openalex   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca ²⁺ -binding sites [PDF]

, 2002
Nicolas Le Novère, Thomas Grütter, Jean‐Pierre Changeux   +2 more
openalex   +1 more source

Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells

The Journal of Physiology, EarlyView.
Abstract figure legend: We tested the effects of expressing the bacterial voltage‐gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expression decreases expression of endogenous voltage‐gated sodium channels (left), reduces action potential firing (upper) and prevents learning (lower). However,
Katie Greenin‐Whitehead, Eyal Rozenfeld, Anthony Moreno‐Sanchez, Melissa W. Tan, Kurtulus Kullu, Jessica Ausborn, Moshe Parnas, Andrew C. Lin   +7 more
wiley   +1 more source

The Calcium Sensor Protein Visinin-like Protein-1 Modulates the Surface Expression and Agonist Sensitivity of the α4β2 Nicotinic Acetylcholine Receptor [PDF]

, 2002
Lin Lin, Elisabeth Jeanclos, Magdalen W. Treuil, Karl‐Heinz Braunewell, Eckart D. Gundelfinger, René Anand   +5 more
openalex   +1 more source

Discrepancies Between Recommendations in Evidence‐Based Guidelines for the Management of Obesity in Adolescents and Adults: An Evidence Map

Obesity Reviews, Volume 26, Issue 10, October 2025.
ABSTRACT Background/Aim The aim of this evidence map is to provide a systematic overview of evidence‐based guidelines for the management of obesity and to highlight discrepancies between recommendations for the pediatric and adult populations. Knowing about these discrepancies may be relevant during the transition from pediatrics to adult healthcare to
Jana Brauchmann, Luise Laudenbach, Philipp Kapp, Kathrin Grummich, Julia Lischka, Nicole Vanersa, Edrienny Patricia Alves Accioly Rocha, Gundula Ernst, Joerg J. Meerpohl, Antje Tannen, Daniel Weghuber, Susann Weihrauch‐Blüher, Susanna Wiegand, Gabriel Torbahn   +13 more
wiley   +1 more source