Results 161 to 170 of about 597,674 (298)

Prioritizing Modifiable Risk Factors for Cardiovascular Diseases in Adults With Hypertension: A Prospective Cohort Study

Med Research, EarlyView.
This study examined the relative contributions of modifiable risk factors to cardiovascular diseases in adults with hypertension. More favorable risk factor profiles were consistently associated with lower risks across all outcomes. Beyond blood pressure, nicotine exposure showed comparatively larger population attributable fractions.
Shengtao Wei, Dashan Zheng, Lan Chen, Zitong Zhuang, Zihan Lin, Junguo Zhang, Peng Hu, Zijun Yang, Zhen‐He Huang, Bing Zhang, Hualiang Lin   +10 more
wiley   +1 more source

Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. [PDF]

Mol Neurobiol, 2023
Wadsworth HA, Anderson EQ, Williams BM, Ronström JW, Moen JK, Lee AM, McIntosh JM, Wu J, Yorgason JT, Steffensen SC.   +9 more
europepmc   +1 more source

Associations Between Cumulative Head Trauma and Self‐Reported Parkinsonism and Parkinson's Disease in Former Soccer Players

Movement Disorders, EarlyView.
Abstract Background Cumulative head trauma, encompassing repetitive head impacts (RHI) and traumatic brain injury (TBI), has been associated with later‐life neurodegenerative disease. Studies on parkinsonism/Parkinson's disease (PD) have evaluated RHI and TBI in isolation, yielding mixed results.
Annalise E. Miner, Matthew J. Kmiecik, Niharika Namburi, Nathaniel Dunckley, Charles H. Adler, Erika D. Driver‐Dunckley, Christopher J. Nowinski, Joshua Gottesman, Yorghos Tripodis, Robert A. Stern, Ann C. McKee, Thor D. Stein, Jesse Mez, Farren B.S. Briggs, Michael L. Alosco   +14 more
wiley   +1 more source

Cell death in the lateral geniculate nucleus, and its possible relationship with nicotinic receptors and sudden infant death syndrome (SIDS). [PDF]

Mol Neurobiol, 2023
Chang C, Vivekanandarajah A, Waters KA, Machaalani R.   +3 more
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Rabies virus glycoprotein variants modulate neuronal nicotinic receptors in a conformation-dependent manner. [PDF]

Sci Rep
Akaberi SM, Yeasmin S, Sapkota P, Sharma K, Schulte M.   +4 more
europepmc   +1 more source

Nicotine as an odorant : a biochemical and electrophysiological study of receptors for nicotine in the olfactory epithelium of the rat [PDF]

The results suggest that nicotine vapour stimulates an in vitro olfactory preparation in three strains of rat and two strains of mouse, in a manner similar to known odorants.
Edwards, Damian Andrew
core  

Exploring the Value of Quantitative Muscle Ultrasound in Neuromuscular Junction Disorders: A Pilot Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Quantitative muscle ultrasound (QMUS) is a validated technique for assessing muscle pathology, yet its role in disorders primarily affecting the neuromuscular junction (NMJ) remains unclear. This pilot study aimed to explore whether QMUS is associated with structural muscle changes in patients with acquired or genetic NMJ ...
Artor Pogosean, Maarika Liik, Nens van Alfen, Anna Rostedt Punga   +3 more
wiley   +1 more source

Functional Expression of Nicotinic Receptors on iPSC-Derived Astrocytes and Signalling Disturbances by a Panel of Neonicotinoid Pesticides and Their Metabolites. [PDF]

Int J Mol Sci
Cöllen E, Wolfbeisz C, Leisner H, Grillberger K, Kormann J, Tanaskov Y, Dreser N, Karreman C, Hartung T, Ecker G, Kraushaar U, Leist M.   +11 more
europepmc   +1 more source

Interaction of α9α10 Nicotinic Receptors With Peptides and Proteins From Animal Venoms. [PDF]

Front Cell Neurosci, 2021
Tsetlin V, Haufe Y, Safronova V, Serov D, Shadamarshan P, Son L, Shelukhina I, Kudryavtsev D, Kryukova E, Kasheverov I, Nicke A, Utkin Y.   +11 more
europepmc   +1 more source