Results 1 to 10 of about 59,868 (281)

Nifedipine promotes the proliferation and migration of breast cancer cells. [PDF]

open access: yesPLoS ONE, 2014
Nifedipine is widely used as a calcium channel blocker (CCB) to treat angina and hypertension,but it is controversial with respect the risk of stimulation of cancers. In this study, we demonstrated that nifedipine promoted the proliferation and migration
Dong-Qing Guo   +3 more
doaj   +4 more sources

Nifedipine Improves the Ketogenic Diet Effect on Insulin-Resistance-Induced Cognitive Dysfunction in Rats. [PDF]

open access: yesPharmaceuticals (Basel)
Insulin resistance, induced by high fructose consumption, affects cognitive function negatively. Nifedipine may be suggested for neurological disorders.
Abdel-Kareem NM   +6 more
europepmc   +2 more sources

Efficacy and safety of oral nifedipine with or without vaginal progesterone in the management of threatened preterm labor [PDF]

open access: yesInternational Journal of Reproductive BioMedicine, 2019
Background Preterm labor (PTL) is a serious emergency wherein robust management is imperative for achieving improved outcome. Objective To evaluate the efficacy and safety of nifedipine alone vs nifedipine with vaginal ...
Bushra Ashraf
doaj   +4 more sources

Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib

open access: yesFrontiers in Pharmacology, 2022
Aim: It has been found that the co-administration of nifedipine with apatinib could cause exposure changes of nifedipine in vivo. But, whether this pharmacokinetic drug-drug interaction (DDI) between nifedipine and apatinib could enhance the ...
Hongrui Liu   +8 more
doaj   +1 more source

Phenomenological analysis of simple ion channel block in large populations of uncoupled cardiomyocytes [PDF]

open access: yesMathematical Medicine & Biology, 2023, 2023
Current understanding of arrhythmia mechanisms and design of anti-arrhythmic drug therapies hinges on the assumption that myocytes from the same region of a single heart have similar, if not identical, action potential waveforms and drug responses. On the contrary, recent experiments reveal significant heterogeneity in uncoupled healthy myocytes both ...
arxiv   +1 more source

A remote hypertension management program clinical algorithm

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1147-1162, December 2022., 2022
Abstract Introduction Hypertension is the leading risk factor for death, affecting over one billion people worldwide, yet control rates are poor and stagnant. We developed a remote hypertension management program that leverages digitally transmitted home blood pressure (BP) measurements, algorithmic care pathways, and patient–navigator communications ...
Hunter Nichols   +3 more
wiley   +1 more source

Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

open access: yesHypertension in Pregnancy, 2022
Objectives This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy.
Hui-Zhen Wu   +5 more
doaj   +1 more source

Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial

open access: yesJournal of Family and Reproductive Health, 2021
Objective: Recently, sildenafil as a drug effective in relaxing smooth muscles can be used as an adjunct to delay the onset of uterine contractions and therefore the occurrence of preterm labor.
Elham Mohammadi   +4 more
doaj   +1 more source

Evaluation of P53 protein expression in gingival tissues of patients with chronic periodontitis by immunohistochemistry methods

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1348-1353, December 2022., 2022
Abstract Objective Periodontitis is one of the most important periodontal diseases that can be affected by many factors. Although the mechanism of periodontitis development is not yet fully understood, previous studies suggest that apoptosis may be one of the pathological factors that can affect the process of the disease by destroying old and damaged ...
Samaneh Minabian   +4 more
wiley   +1 more source

Nifedipine Potentiates Susceptibility of Salmonella Typhimurium to Different Classes of Antibiotics

open access: yesAntibiotics, 2021
The calcium channel blocker nifedipine induces cellular iron export, thereby limiting the availability of the essential nutrient iron for intracellular pathogens, resulting in bacteriostatic activity.
David Haschka   +5 more
doaj   +1 more source

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