Results 1 to 10 of about 63,212 (286)

A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine

open access: yesMolecules, 2020
Proliposomes were used to improve the solubility and oral bioavailability of nifedipine. Nifedipine proliposomes were prepared by methanol injection-spray drying method.
Ye Bi   +6 more
doaj   +2 more sources

Nifedipine Improves the Ketogenic Diet Effect on Insulin-Resistance-Induced Cognitive Dysfunction in Rats [PDF]

open access: yesPharmaceuticals
Insulin resistance, induced by high fructose consumption, affects cognitive function negatively. Nifedipine may be suggested for neurological disorders.
Nancy M. Abdel-Kareem   +6 more
doaj   +2 more sources

Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib

open access: yesFrontiers in Pharmacology, 2022
Aim: It has been found that the co-administration of nifedipine with apatinib could cause exposure changes of nifedipine in vivo. But, whether this pharmacokinetic drug-drug interaction (DDI) between nifedipine and apatinib could enhance the ...
Hongrui Liu   +8 more
doaj   +1 more source

Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial

open access: yesJournal of Family and Reproductive Health, 2021
Objective: Recently, sildenafil as a drug effective in relaxing smooth muscles can be used as an adjunct to delay the onset of uterine contractions and therefore the occurrence of preterm labor.
Elham Mohammadi   +4 more
doaj   +1 more source

Phenomenological analysis of simple ion channel block in large populations of uncoupled cardiomyocytes [PDF]

open access: yesMathematical Medicine & Biology, 2023, 2023
Current understanding of arrhythmia mechanisms and design of anti-arrhythmic drug therapies hinges on the assumption that myocytes from the same region of a single heart have similar, if not identical, action potential waveforms and drug responses. On the contrary, recent experiments reveal significant heterogeneity in uncoupled healthy myocytes both ...
arxiv   +1 more source

Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

open access: yesHypertension in Pregnancy, 2022
Objectives This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy.
Hui-Zhen Wu   +5 more
doaj   +1 more source

Evaluation of Cartilage Integrity Following Administration of Oral and Intraarticular Nifedipine in a Murine Model of Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no effective treatments are currently available. Arterial hypertension is a common comorbidity in OA patients, and antihypertensive drugs, such as nifedipine (NIF),
Viktorija Aleksiuk   +8 more
doaj   +1 more source

Nifedipine Potentiates Susceptibility of Salmonella Typhimurium to Different Classes of Antibiotics

open access: yesAntibiotics, 2021
The calcium channel blocker nifedipine induces cellular iron export, thereby limiting the availability of the essential nutrient iron for intracellular pathogens, resulting in bacteriostatic activity.
David Haschka   +5 more
doaj   +1 more source

Effects of nifedipine on fetal pulmonary blood flow in preterm labor

open access: yesPerinatal Journal, 2021
Objective To determine the effect of nifedipine on the fetal pulmonary system by acceleration/ejection time ratio of the fetal main pulmonary artery Doppler waveform.
Şule Göncü Ayhan   +3 more
doaj   +1 more source

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