Results 1 to 10 of about 66,702 (306)

Development of Nifedipine Phytantriol-Based Cubosomes and In Vitro Simulation of Administration Through Pediatric Feeding Tubes [PDF]

Pharmaceutics
Background/Objectives: This study focused on developing an organic solvent-free formulation of phytantriol-based cubosomes for nifedipine delivery.
Lorena Almeida Lima, Euler Eduardo Lisboa de Moura, Schauana Freitas Fraga, Renata Vidor Contri, Irene Clemes Külkamp-Guerreiro   +4 more
doaj   +2 more sources

Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib

Frontiers in Pharmacology, 2022
Aim: It has been found that the co-administration of nifedipine with apatinib could cause exposure changes of nifedipine in vivo. But, whether this pharmacokinetic drug-drug interaction (DDI) between nifedipine and apatinib could enhance the ...
Hongrui Liu, Yiqun Yu, Lu Liu, Chunyan Wang, Nan Guo, Xiaojuan Wang, Xiaoqiang Xiang, Xiaoqiang Xiang, Bing Han   +8 more
doaj   +1 more source

Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

Hypertension in Pregnancy, 2022
Objectives This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy.
Hui-Zhen Wu, Yuan Cheng, Ding Yu, Ji-Bin Li, Yun-Fa Jiang, Zhong-Ning Zhu   +5 more
doaj   +1 more source

Nifedipine Potentiates Susceptibility of Salmonella Typhimurium to Different Classes of Antibiotics

Antibiotics, 2021
The calcium channel blocker nifedipine induces cellular iron export, thereby limiting the availability of the essential nutrient iron for intracellular pathogens, resulting in bacteriostatic activity.
David Haschka, Manuel Grander, Johannes Eibensteiner, Stefanie Dichtl, Sabine Koppelstätter, Günter Weiss   +5 more
doaj   +1 more source

Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial

Journal of Family and Reproductive Health, 2021
Objective: Recently, sildenafil as a drug effective in relaxing smooth muscles can be used as an adjunct to delay the onset of uterine contractions and therefore the occurrence of preterm labor.
Elham Mohammadi, Somayyeh Noei Teymoordash, Ali Reza Norouzi, Fatemeh Norouzi, Hamid Reza Norouzi   +4 more
doaj   +1 more source

A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine

Molecules, 2020
Proliposomes were used to improve the solubility and oral bioavailability of nifedipine. Nifedipine proliposomes were prepared by methanol injection-spray drying method.
Ye Bi, Bingcong Lv, Lianlian Li, Robert J. Lee, Jing Xie, Zhidong Qiu, Lesheng Teng   +6 more
doaj   +1 more source

WHICH ONE IS BETTER FOR TOCOLYSIS IN PRE-TERM LABOR?: ORAL NIFEDIPINE VS TRANSDER-MAL NITROGLYCERIN PATCH

National Journal of Medical Research, 2023
Introduction: Preterm labour follows a spontaneous commencement of labour in two-thirds of preterm birth instances. Obstetricians must consider both treatment options for the management of preterm.
Ashish P Kalburgi, Nitin Kshirsagar
doaj   +1 more source

Comparative efficacy of generic nifedipine versus brand‐name amlodipine for hypertension management in Taiwan

The Journal of Clinical Hypertension, 2022
The control rate of hypertension remains concerning, indicating the requirement for better management strategies. The calcium channel blockers brand‐name amlodipine and nifedipine with extended‐release formulations demonstrate similar clinical efficacy ...
Hao‐Wei Lee, Chin‐Chou Huang, Hsin‐Bang Leu, Yenn‐Jiang Lin   +3 more
doaj   +1 more source

Evaluation of Cartilage Integrity Following Administration of Oral and Intraarticular Nifedipine in a Murine Model of Osteoarthritis

Biomedicines, 2023
Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no effective treatments are currently available. Arterial hypertension is a common comorbidity in OA patients, and antihypertensive drugs, such as nifedipine (NIF),
Viktorija Aleksiuk, Justinas Baleisis, Gailute Kirdaite, Ilona Uzieliene, Jaroslav Denkovskij, Paulius Bernotas, Tatjana Ivaskiene, Ali Mobasheri, Eiva Bernotiene   +8 more
doaj   +1 more source

Nifedipine overdose [PDF]

Clinical Cardiology, 1988
AbstractOverdose with 300 mg of nifedipine in a 54‐year‐old woman led to profound hypotension and reflex tachycardia. The patient was treated with intravenous fluids, calcium gluconate, and dopamine. Cardiac rhythm disturbances, hypoglycemia, and myocardial depression were not found. Recovery was rapid and uneventful. The clinical aspects of nifedipine
D, Whitebloom, J, Fitzharris
openaire   +2 more sources