Results 1 to 10 of about 37,594 (237)

Efficacy and Safety of Nifedipine as a Tocolytic Agent in Preterm Labor

open access: yesJournal of Pharmacy and Bioallied Sciences
Objectives: To study the success or failure of pregnancy with nifedipine and the side effects of nifedipine. Materials and Methods: A prospective observational cohort study was conducted on 138 pregnant women between 28 and 34 weeks of gestation ...
Neelam Nalini   +3 more
doaj   +2 more sources

Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis

open access: goldHypertension in Pregnancy, 2023
Aim To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP). Methods The primary outcomes were the required time to achieve target blood pressure (RTATBP), systolic blood pressure (SBP) and ...
Minghui Ou   +4 more
doaj   +2 more sources

Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets. [PDF]

open access: goldPLoS ONE, 2015
The platelet-derived soluble CD40L (sCD40L) release plays a critical role in the development of atherosclerosis. Nifedipine, a dihydropyridine-based L-type calcium channel blocker (CCB), has been reported to have an anti-atherosclerotic effect beyond its
Tso-Hsiao Chen   +3 more
doaj   +3 more sources

Development of Nifedipine Phytantriol-Based Cubosomes and In Vitro Simulation of Administration Through Pediatric Feeding Tubes [PDF]

open access: yesPharmaceutics
Background/Objectives: This study focused on developing an organic solvent-free formulation of phytantriol-based cubosomes for nifedipine delivery.
Lorena Almeida Lima   +4 more
doaj   +2 more sources

Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib

open access: yesFrontiers in Pharmacology, 2022
Aim: It has been found that the co-administration of nifedipine with apatinib could cause exposure changes of nifedipine in vivo. But, whether this pharmacokinetic drug-drug interaction (DDI) between nifedipine and apatinib could enhance the ...
Hongrui Liu   +8 more
doaj   +1 more source

Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

open access: yesHypertension in Pregnancy, 2022
Objectives This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy.
Hui-Zhen Wu   +5 more
doaj   +1 more source

Nifedipine overdose [PDF]

open access: yesClinical Cardiology, 1988
AbstractOverdose with 300 mg of nifedipine in a 54‐year‐old woman led to profound hypotension and reflex tachycardia. The patient was treated with intravenous fluids, calcium gluconate, and dopamine. Cardiac rhythm disturbances, hypoglycemia, and myocardial depression were not found. Recovery was rapid and uneventful. The clinical aspects of nifedipine
D, Whitebloom, J, Fitzharris
openaire   +2 more sources

Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial

open access: yesJournal of Family and Reproductive Health, 2021
Objective: Recently, sildenafil as a drug effective in relaxing smooth muscles can be used as an adjunct to delay the onset of uterine contractions and therefore the occurrence of preterm labor.
Elham Mohammadi   +4 more
doaj   +1 more source

Nifedipine Potentiates Susceptibility of Salmonella Typhimurium to Different Classes of Antibiotics

open access: yesAntibiotics, 2021
The calcium channel blocker nifedipine induces cellular iron export, thereby limiting the availability of the essential nutrient iron for intracellular pathogens, resulting in bacteriostatic activity.
David Haschka   +5 more
doaj   +1 more source

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