Results 141 to 150 of about 66,702 (306)

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Regional cardioprotection by subselective intracoronary nifedipine is not due to enhanced collateral flow during coronary angioplasty [PDF]

, 1987
Gheorghe Pop, Patrick W. Serruys, Federico Piscione, Pim J. de Feyter, Marcel van den Brand, Tom Huizer, Jan Willem de Feyter, Paul G. Hugenholtz   +7 more
openalex   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Physical properties and solubility studies of Nifedipine-PEG 1450/HPMCAS-HF solid dispersions [PDF]

, 2018
Low-order high-energy nifedipine (NIF) solid dispersions (SDs) were generated by melt solvent amorphization with polyethylene glycol (PEG) 1450 and hypromellose acetate succinate (HPMCAS-HF) to increase NIF solubility while achieving acceptable physical ...
Chougule, Mahavir B., Dave, Vivek S, Gavireddi, Monika, Gupta, Deepak, Haware, Rahul V., Stagner, William C, Vinjamuri, Bhavani Prasad   +6 more
core   +1 more source

Effect of Nifedipine on Frequency-Force Relationship in Isolated Dog Left Ventricular Muscle.

, 1978
Shigetoshi Chiba, Yasuyuki Furukawa, Miyoharu Kobayashi   +2 more
openalex   +1 more source

Nifedipine augments haloperidol in the treatment of Tourette syndrome [PDF]

, 1988
Norman E. Alessi, Marlene Walden, P S Hsieh   +2 more
openalex   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Nifedipine therapy for Prinzmetal's angina.

, 1978
James E. Muller, Stephen Gunther
openalex   +1 more source

Enhancement of vasoconstrictor and attenuation of vasodilator effects of 5-hydroxytryptamine by the calcium channel blockers nimodipine and nifedipine in the pig [PDF]

, 1987
Dirk J. Duncker, Marc J. Yland, Leo P. Van der Weij, Pramod R. Saxena, Pieter D. Verdouw   +4 more
openalex   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

The Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier, Dobromir Dobrev, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source