Results 11 to 20 of about 67,449 (286)

Evaluation of Cartilage Integrity Following Administration of Oral and Intraarticular Nifedipine in a Murine Model of Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no effective treatments are currently available. Arterial hypertension is a common comorbidity in OA patients, and antihypertensive drugs, such as nifedipine (NIF),
Viktorija Aleksiuk   +8 more
doaj   +1 more source

Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth

open access: yesScientific Reports, 2023
Spontaneous preterm birth is the leading cause of perinatal morbidity and mortality. Tocolytics are drugs used in cases of imminent preterm birth to inhibit uterine contractions.
Bridget M. Arman   +8 more
doaj   +1 more source

Tocolysis with nifedipine versus atosiban and perinatal outcome: an individual participant data meta-analysis

open access: yesBMC Pregnancy and Childbirth, 2022
Background Worldwide, nifedipine and atosiban are the two most commonly used tocolytic agents for the treatment of threatened preterm birth. The aim of this study was to evaluate the effectiveness of nifedipine and atosiban in an individual participant ...
Tijn M. S. van Winden   +9 more
doaj   +1 more source

School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12-Year Follow-Up of the APOSTEL 2 Trial. [PDF]

open access: yesBJOG
ABSTRACT Objective To evaluate school performance at 12 years of age in children prenatally exposed to maintenance tocolysis with nifedipine versus placebo. Design 12‐year follow‐up of the multicentre APOSTEL 2 trial, in which participants with threatened preterm birth between 26+0 and 32+2 weeks of gestation, who remained pregnant after initial 48‐h ...
van der Windt LI   +8 more
europepmc   +2 more sources

Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets. [PDF]

open access: yesPLoS ONE, 2015
The platelet-derived soluble CD40L (sCD40L) release plays a critical role in the development of atherosclerosis. Nifedipine, a dihydropyridine-based L-type calcium channel blocker (CCB), has been reported to have an anti-atherosclerotic effect beyond its
Tso-Hsiao Chen   +3 more
doaj   +1 more source

Therapy for nifedipine-induced gingival overgrowth by saireito in rats

open access: yesEuropean Journal of Medical Research, 2009
Objective A calcium antagonist, nifedipine, causes gingival overgrowth as a side effect. It has been confirmed that the Japanese traditional medicine, Saireito, inhibits the nifedipine-induced proliferation of gingival fibroblasts in vitro.
Hattori T   +5 more
doaj   +1 more source

DIHYDROPYRIDINE CALCIUM ANTAGONISTS. POSITION OF NIFEDIPINE IN MODERN CARDIOLOGY PRACTICE

open access: yesРациональная фармакотерапия в кардиологии, 2016
Position of nifedipine in modern cardiology practice is highlighted. Nifedipine usage for arterial hypertension therapy , including combined one, stroke prevention, treatment of hypertensive crisis and ischemic heart disease is considered.
A. A. Garganeeva
doaj   +1 more source

Atosiban in the management of preterm labour [PDF]

open access: yes, 2011
Peer reviewedPublisher ...
Bhattacharya, Sohinee   +3 more
core   +3 more sources

Development of a UV-Stabilized Topical Formulation of Nifedipine for the Treatment of Raynaud Phenomenon and Chilblains

open access: yesPharmaceutics, 2019
Raynaud’s Phenomenon is a vascular affliction resulting in pain and blanching of the skin caused by excessive and prolonged constriction of arterioles, usually due to cold exposure.
Ellen K. Wasan   +10 more
doaj   +1 more source

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