Results 21 to 30 of about 3,081 (227)
Decoration of nanovesicles with pH (low) insertion peptide (pHLIP) for targeted delivery [PDF]
, 2018 Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells.
Andreev O. A. +9 more
core +1 more source
Asian Journal of Pharmaceutical Research and Development, 2023 Pharmaceutical such achemicals can be administered locally to sick locations using target-specific drug-delivery devices.Some of the carriers used in various drug delivery techniques includesynthetic polymers, serum proteins, and immune globulins, liposomes, and microspheres.
Redasani Vivekkumar +2 more
openaire +1 more source
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]
, 2004 The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Couet, William +5 more
core +1 more source
Scientific Reports, 2022 Targeted drug delivery and increasing the biological activity of drugs is one of the recent challenges of pharmaceutical researchers. Niosomes are one of the new targeted drug delivery systems that enhances the biological properties of drugs.
Abbas Haddadian +15 more
doaj +1 more source
Chondrogenic Differentiation of Human Mesenchymal Stem Cells via SOX9 Delivery in Cationic Niosomes
Pharmaceutics, 2022 Gene transfer to mesenchymal stem cells constitutes a powerful approach to promote their differentiation into the appropriate cartilage phenotype. Although viral vectors represent gold standard vehicles, because of their high efficiency, their use is ...
Natalia Carballo-Pedrares +4 more
doaj +1 more source
Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine [PDF]
, 2015 The present study aimed to evaluate the incorporation of protamine into niosome/DNA vectors to analyze the potential application of this novel ternary formulation to deliver the pCMS-EGFP plasmid into the rat retina.
Agirre, Mireia +11 more
core +2 more sources
Pharmaceuticals, 2021 Breast cancer is one of the most prevalent causes of cancer mortality in women. In order to increase patient prognosis and survival rates, new technologies are urgently required to deliver therapeutics in a more effective and efficient manner.
Hamidreza Sahrayi +11 more
doaj +1 more source
Niosomes based on synthetic cationic lipids for gene delivery: The influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells [PDF]
, 2015 We designed niosomes based on three lipids that differed only in the polar-head group to analyze their influence on the transfection efficiency. These lipids were characterized by small-angle X-ray scattering before being incorporated into the niosomes ...
Agirre, Mireia +10 more
core +1 more source
Nghiên cứu bào chế niosome metformin
Tạp chí Khoa học Đại học Cần Thơ, 2016 Metformin là thuốc trị đái tháo đường (ĐTĐ) sử dụng điều trị bước đầu dành cho bệnh nhân ĐTĐ type 2 theo phác đồ điều trị của Hiệp hội đái tháo đường Hoa Kỳ (ADA). Tuy nhiên, thuốc thường hấp thu nhanh chóng, thời gian bán thải ngắn.
Lê Thùy Dung +2 more
doaj +1 more source
Pharmaceutics, 2022 This study aimed to develop a chemically stable niosomal eye drop containing fosinopril (FOS) for lowering intraocular pressure. The effects of cyclodextrin (CD), surfactant types and membrane stabilizer/charged inducers on physiochemical and chemical ...
Hay Marn Hnin +5 more
doaj +1 more source