Results 21 to 30 of about 1,424 (179)

Formulation and Optimization of Zidovudine Niosomes [PDF]

AAPS PharmSciTech, 2010
Zidovudine (AZT) is commonly used to treat patients with AIDS, but it is limited by toxicity and high dosing needs. Alternative formulations have been proposed to overcome these drawbacks. The objective of this study was to evaluate process-related variables like hydration and sonication time, rotation speed of evaporation flask, and the effects of ...
Kandasamy, Ruckmani, Veintramuthu, Sankar   +1 more
openaire   +2 more sources

Niosomes-loaded selenium nanoparticles as a new approach for enhanced antibacterial, anti-biofilm, and anticancer activities

Scientific Reports, 2022
Targeted drug delivery and increasing the biological activity of drugs is one of the recent challenges of pharmaceutical researchers. Niosomes are one of the new targeted drug delivery systems that enhances the biological properties of drugs.
Abbas Haddadian, Farnoush Falahi Robattorki, Hedieh Dibah, Ali Soheili, Erfan Ghanbarzadeh, Nasrin Sartipnia, Shadi Hajrasouliha, Kamal Pasban, Romina Andalibi, Mojtaba Hedayati Ch, Arezou Azari, Arman Chitgarzadeh, Aliasghar Bagheri Kashtali, Fatemeh Mastali, Hassan Noorbazargan, Amir Mirzaie   +15 more
doaj   +1 more source

Co-Delivery of Letrozole and Cyclophosphamide via Folic Acid-Decorated Nanoniosomes for Breast Cancer Therapy: Synergic Effect, Augmentation of Cytotoxicity, and Apoptosis Gene Expression

Pharmaceuticals, 2021
Breast cancer is one of the most prevalent causes of cancer mortality in women. In order to increase patient prognosis and survival rates, new technologies are urgently required to deliver therapeutics in a more effective and efficient manner.
Hamidreza Sahrayi, Elham Hosseini, Sara Karimifard, Nazanin Khayam, Seyed Mohammadmahdi Meybodi, Sahar Amiri, Mahsa Bourbour, Bahareh Farasati Far, Iman Akbarzadeh, Mohammed Bhia, Clare Hoskins, Chaiyavat Chaiyasut   +11 more
doaj   +1 more source

Nghiên cứu bào chế niosome metformin

Tạp chí Khoa học Đại học Cần Thơ, 2016
Metformin là thuốc trị đái tháo đường (ĐTĐ) sử dụng điều trị bước đầu dành cho bệnh nhân ĐTĐ type 2 theo phác đồ điều trị của Hiệp hội đái tháo đường Hoa Kỳ (ADA). Tuy nhiên, thuốc thường hấp thu nhanh chóng, thời gian bán thải ngắn.
Lê Thùy Dung, Lê Trọng Nghĩ, Lê Thanh Phước   +2 more
doaj   +1 more source

Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery

Pharmaceutics, 2022
This study aimed to develop a chemically stable niosomal eye drop containing fosinopril (FOS) for lowering intraocular pressure. The effects of cyclodextrin (CD), surfactant types and membrane stabilizer/charged inducers on physiochemical and chemical ...
Hay Marn Hnin, Einar Stefánsson, Thorsteinn Loftsson, Rathapon Asasutjarit, Dusadee Charnvanich, Phatsawee Jansook   +5 more
doaj   +1 more source

Niosomes: An Update

International Journal of Current Pharmaceutical Review and Research, 2017
Over decades researchers are striving to use the drugs in an efficient manner to treat various diseases. The efficient use can be explained as reduced dose, reduced side effects, reduced dosage frequency, greater patient compliance and maximum concentration of the drug at the site of action so as to reduce the undue exposure to the entire body.
Shilpi Arora, , Yashwant
openaire   +3 more sources

Green Preparation, Characterization, Wound Healing Assessment, and Histopathological Evaluation of Vitamin A Encapsulated in Niosome and Solid Lipid Nanoparticle [PDF]

Pharmaceutical Sciences
Background: The purpose of the current work was to manufacture vitamin A (Vit A) niosome and solid lipid nanoparticle (SLN) using an ultrasonic approach and to evaluate its effect on wound healing.
Seyyed Mobin Rahimnia, Majid Saeedi, Katayoun Morteza-Semnani, Jafar Akbari, Maryam Ghasemi, Shidrokh Abootorabi, Reza Negarandeh, Mohammad Eghbali, Behrouz Jafarkhani, Mahshid Boskabadi, Seyyed Mohammad Hassan Hashemi   +10 more
doaj   +1 more source

Effects of Imipenem-containing Niosome nanoparticles against high prevalence methicillin-resistant Staphylococcus Epidermidis biofilm formed

Scientific Reports, 2022
We aim to assess the antibacterial and anti-biofilm properties of Niosome-encapsulated Imipenem. After isolating Staphylococcus epidermidis isolates and determining their microbial sensitivity, their ability to form biofilms was examined using plate ...
Tohid Piri-Gharaghie, Neda Jegargoshe-Shirin, Sara Saremi-Nouri, Seyed-hossein Khademhosseini, Eskandar Hoseinnezhad-lazarjani, Aezam Mousavi, Hamidreza Kabiri, Negin Rajaei, Anali Riahi, Ali Farhadi-Biregani, Sadegh Fatehi-Ghahfarokhi   +10 more
doaj   +1 more source

Preparation and Characterization of Niosomes for Bacteriophage Delivery. [PDF]

Small Sci
Vesicular nanocarriers, such as niosomes, are versatile systems for delivering therapeutic agents, including small molecules, proteins, enzymes, nucleic acids, and other biologics. Herein, the encapsulation of bacteriophages within niosomes is investigated, expanding the conventional application of these carriers. Formulations are prepared with varying
George AH, Jelinek P, Benešík M, Košiarčiková S, Mikšátko J, Pečurlić I, Moša M, Šoóš M.   +7 more
europepmc   +5 more sources

Novel Vesicular Formulation Based on a Herbal Extract Loaded with Niosomes and Evaluation of Its Antimicrobial and Anticancer Potential

Microbiology Research, 2023
This study aimed to enhance the anticancer and antibacterial properties of Pistacia atlantica through a new parenteral formulation. The innovative approach involved loading P.
Nouf M. Al-Enazi, Khawla Alsamhary, Fuad Ameen, Marcos Augusto Lima Nobre   +3 more
doaj   +1 more source