Results 101 to 110 of about 1,396 (170)

Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone

One approach to interrupting the transmission of insect-borne diseases that is successfully used in veterinary medicine is exploiting the ability of antiparasitic drugs to make vertebrate blood toxic for blood-feeding insects.
Burrows, Jeremy N., Rose, Clair, Biagini, Giancarlo, Trett, Anna, Sterkel, Marcos, Regnault, Clement, Acosta-Serrano, Alvaro, Leroy, Didier, Ranganath, Lakshminarayan R., García, Natalia, Barrett, Michael P., McGuinness, Dagmara, Haines, Lee R., Aljayyoussi, Ghaith   +13 more
core   +1 more source

Therapeutic adenine base editor with minimized off-target effects. [PDF]

Protein Cell
Sun Y, Yan N, Feng H, Lu H, Zuo Z, Zhou C, Zuo E.   +6 more
europepmc   +1 more source

Unveiling the unexpected: refractory rickets as an uncommon presentation of tyrosinemia type I. [PDF]

BMC Pediatr
Ramanna MB, Kamate M, Koppad B.
europepmc   +1 more source

Harliku (nitisinone): first FDA-approved disease-modifying therapy for alkaptonuria. [PDF]

Ann Med Surg (Lond)
Chandani HK, Hujjat SFZ, Chandani DK, Khan MS, Mahmoud A.   +4 more
europepmc   +1 more source

Overcoming the cytosine base editing barrier: Virus-like particles with uracil-DNA glycosylase inhibition unlocking the clinical potential. [PDF]

Clin Transl Med
Wu Y, Zhu X, Zhu J, Chen J, Hong J.
europepmc   +1 more source

Spontaneous Achilles tendon rupture as the initial presentation of ochronosis: a case report. [PDF]

Int J Surg Case Rep
Al-Zagebah A, Elazab M, Muhtaseb R, Tamimi SNS, Makhlouf TZ.   +4 more
europepmc   +1 more source

OGFOD1: a critical mediator of chemoresistance in acute myeloid leukemia. [PDF]

Front Pharmacol
Qiu T, Li P, Tan L, Wu S, Luo Q.
europepmc   +1 more source

Assessing the risk of cataracts associated with medications: A pharmacovigilance analysis of the FAERS database. [PDF]

Medicine (Baltimore)
Chen H, Hou J, Ouyang L, He G, Huang J.
europepmc   +1 more source

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer. [PDF]

Mol Med Rep
Chang W, Yuan J, Zhang H, Yu Y, Ma Y, Li M, Li W, Yan H, Sun C, Zhang P, Tian Y, Guo F, Li P, Sun Y.   +13 more
europepmc   +1 more source

New drugs: Nitisinone

Australian Prescriber, 2009
openaire   +1 more source