Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho +9 more
wiley +1 more source
PLoS Genetics, 2015 The assimilation of nitrate, a most important soil nitrogen source, is tightly regulated in microorganisms and plants. In Aspergillus nidulans, during the transcriptional activation process of nitrate assimilatory genes, the interaction between the ...
Andreas Gallmetzer +10 more
doaj +1 more source
Post-Translational Modifications of Nitrate Reductases Autoregulates Nitric Oxide Biosynthesis in Arabidopsis. [PDF]
Int J Mol Sci, 2021 Costa-Broseta Á, Castillo M, León J.
europepmc +1 more source
Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics [PDF]
, 2006 Alcohol dehydrogenases (ADH) participate in the biosynthetic pathway of aroma volatiles in fruit by interconverting aldehydes to alcohols and providing substrates for the formation of esters.
A-RS Chen +47 more
core +2 more sources
Advanced NanoBiomed Research, EarlyView.Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq +5 more
wiley +1 more source
The dual interplay of RAV5 in activating nitrate reductases and repressing catalase activity to improve disease resistance in cassava. [PDF]
Plant Biotechnol J, 2021 Yan Y +9 more
europepmc +1 more source
Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation [PDF]
, 2015 Phytoplankton growth rates are limited by the supply of iron (Fe) in approximately one third of the open ocean, with major implications for carbon dioxide sequestration and carbon (C) biogeochemistry.
Boyd, Philip W. +7 more
core +1 more source
Transferable denitrification capability of thermus thermophilus [PDF]
, 2014 Laboratory-adapted strains of Thermus spp. have been shown to require oxygen for growth, including the model strains T. thermophilus HB27 and HB8. In contrast, many isolates of this species that have not been intensively grown under laboratory conditions
Berenguer, José +4 more
core +1 more source
Ammonium and potassium effect on nitrate assimilation in cucumber seedlings
Acta Societatis Botanicorum Poloniae, 2015 The effect of ammonium present in the induction medium toghether with nitrate on the activity of nitrate reductase (NR), nitrite reductase (NiR), glutamic acid dehydrogenase (GDH) and absorption and accumulation of NO3- in cucumber seedlings were ...
J. Buczek
doaj +1 more source
The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci [PDF]
, 2017 The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which contributes to the modulation of
Alvarez, Hector Manuel +4 more
core +1 more source