Results 91 to 100 of about 7,497 (290)

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Metagenomic potential for and diversity of N‐cycle driving microorganisms in the Bothnian Sea sediment

MicrobiologyOpen, 2017
The biological nitrogen cycle is driven by a plethora of reactions transforming nitrogen compounds between various redox states. Here, we investigated the metagenomic potential for nitrogen cycle of the in situ microbial community in an oligotrophic ...
Olivia Rasigraf, Julia Schmitt, Mike S. M. Jetten, Claudia Lüke   +3 more
doaj   +1 more source

Nitrate transport and assimilation in Aspergillus nidulans

, 2012
In this study, several aspects of nitrate assimilation and transport have been studied using the filamentous fungus Aspergillus nidulans, which has been shown to be safe laboratory organism as judged by it’s pathogenicity towards insect larvae.
Akhtar, Naureen
core  

Identification of an assimilatory nitrate reductase in mutants of Paracoccus denitrificans GB17 deficient in nitrate respiration

, 1997
A Paracoccus denitrificans strain (M6Omega) unable to use nitrate as a terminal electron acceptor was constructed by insertional inactivation of the periplasmic and membrane-bound nitrate reductases.
Little, Phillip J., Berks, B C, Spiro, Stephen, Richardson, D., Spiro, S, Ferguson, Stuart J., Berks, Ben C., Sears, Heather J., Richardson, David J., Sears, H J   +9 more
core   +1 more source

Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA.

PLoS Genetics, 2015
The assimilation of nitrate, a most important soil nitrogen source, is tightly regulated in microorganisms and plants. In Aspergillus nidulans, during the transcriptional activation process of nitrate assimilatory genes, the interaction between the ...
Andreas Gallmetzer, Lucia Silvestrini, Thorsten Schinko, Bernd Gesslbauer, Peter Hortschansky, Christoph Dattenböck, María Isabel Muro-Pastor, Andreas Kungl, Axel A Brakhage, Claudio Scazzocchio, Joseph Strauss   +10 more
doaj   +1 more source

Molecular genetical analysis of the nitrate gene cluster of Aspergillus nidulans

, 2015
Putative DNA clones harbouring the nitrate gene cluster of Aspergillus nidulans was used in a number of transformation experiments to positively identify the clones.
Greaves, Philip Andrew
core  

The dual interplay of RAV5 in activating nitrate reductases and repressing catalase activity to improve disease resistance in cassava. [PDF]

Plant Biotechnol J, 2021
Yan Y, Wang P, Wei Y, Bai Y, Lu Y, Zeng H, Liu G, Reiter RJ, He C, Shi H.   +9 more
europepmc   +1 more source

Phylogenetic tree of nitrate assimilation related genes.

, 2012
This tree was built on concatenated homologous sequences of all three genes (nitrate/nitrite transporter, nitrate reductases, and nitrite reductase) in Ascomycota and Basidiomycota from the subkingdom Dikarya (Materials and Methods) by the ML method.
Yasuyuki Tomita (4707), Takashi Gojobori (2581), Shigehito Ikushima (163453), Hideyuki Tamakawa (163441), Kazuho Ikeo (2984)   +4 more
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Ammonium and potassium effect on nitrate assimilation in cucumber seedlings

Acta Societatis Botanicorum Poloniae, 2015
The effect of ammonium present in the induction medium toghether with nitrate on the activity of nitrate reductase (NR), nitrite reductase (NiR), glutamic acid dehydrogenase (GDH) and absorption and accumulation of NO3- in cucumber seedlings were ...
J. Buczek
doaj   +1 more source