Results 81 to 90 of about 6,837 (257)

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Ammonium and potassium effect on nitrate assimilation in cucumber seedlings

Acta Societatis Botanicorum Poloniae, 2015
The effect of ammonium present in the induction medium toghether with nitrate on the activity of nitrate reductase (NR), nitrite reductase (NiR), glutamic acid dehydrogenase (GDH) and absorption and accumulation of NO3- in cucumber seedlings were ...
J. Buczek
doaj   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Orphan response regulator NnaR is critical for nitrate and nitrite assimilation in Mycobacterium abscessus

Frontiers in Cellular and Infection Microbiology
Mycobacterium abscessus (Mab) is an opportunistic pathogen afflicting individuals with underlying lung disease such as Cystic Fibrosis (CF) or immunodeficiencies.
Breven S. Simcox, Kyle H. Rohde
doaj   +1 more source

Influence of Nitrogen Source and Growth Phase on Extracellular Biosynthesis of Silver Nanoparticles Using Cultural Filtrates of Scenedesmus obliquus

Applied Sciences, 2019
In this study, silver nanoparticles (AgNPs) were green-synthesized extracellularly by the action of bioactive compounds in cultural filtrates of green microalga Scenedesmus obliquus (KY621475).
Osama M. Darwesh, Ibrahim A. Matter, Mohamed F. Eida, Hassan Moawad, You-Kwan Oh   +4 more
doaj   +1 more source

Biochar‐based fertilizers improve nutrient use efficiency in sunflower grown on a subtropical tidal soil

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Improving fertilizer use efficiency is essential for reducing environmental pollution, sustaining agricultural production, and maximizing the economic profitability of crop production systems. This study tested the hypothesis that the formulation strategy of biochar‐based fertilizers, rather than nutrient addition alone, is associated with ...
Md. Al‐Amin, Miftahul Jannat Mim, S. M. Mahbubul Alam, Shamim Mia, M. M. Masud, Gopal Saha, Md. Abdul Kader, Keiji Jindo   +7 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Lowering salivary pH with sugar‐containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice)

British Journal of Clinical Pharmacology, EarlyView.
Acutely lowering salivary pH (with sugar‐containing acidic gum vs. sugar‐free gum) augments salivary nitrate reduction to nitrite, plasma nitrite concentration, and blood pressure lowering with dietary nitrate. Modifying salivary pH reveals a mechanism by which the nitrate‐nitrite‐NO pathway may be upregulated/inhibited, with potential for other ...
Andrew J. Webb, Harriet Clift, Callum Hill, Nur Mousa, Navanithan Arun Jayaraj, Jasmine Quraishi, Charlotte E. Mills, Kevin O'Gallagher   +7 more
wiley   +1 more source

Influence of lead on N03 uptake and reduction in cucumber seedlings

Acta Societatis Botanicorum Poloniae, 2014
The influence of PbCl2 on NO3- uptake and activity level of nitrate (NR) and nitrite MR) reductases in cotyledons and roots of cucumber seedlings was studied.
Marek Burzyński, Adam Grabowski
doaj   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source