Results 71 to 80 of about 503,441 (367)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Nitrogen Starvation Acclimation in Synechococcus elongatus: Redox-Control and the Role of Nitrate Reduction as an Electron Sink

Life, 2015
Nitrogen starvation acclimation in non-diazotrophic cyanobacteria is characterized by a process termed chlorosis, where the light harvesting pigments are degraded and the cells gradually tune down photosynthetic and metabolic activities.
Alexander Klotz, Edgar Reinhold, Sofía Doello, Karl Forchhammer   +3 more
doaj   +1 more source

Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA. [PDF]

PLoS Genetics, 2015
The assimilation of nitrate, a most important soil nitrogen source, is tightly regulated in microorganisms and plants. In Aspergillus nidulans, during the transcriptional activation process of nitrate assimilatory genes, the interaction between the ...
Andreas Gallmetzer, Lucia Silvestrini, Thorsten Schinko, Bernd Gesslbauer, Peter Hortschansky, Christoph Dattenböck, María Isabel Muro-Pastor, Andreas Kungl, Axel A Brakhage, Claudio Scazzocchio, Joseph Strauss   +10 more
doaj   +1 more source

Nitrate reductase from squash: cDNA cloning and nitrate regulation [PDF]

Proceedings of the National Academy of Sciences, 1986
The assimilation of nitrate in plants involves the reduction of nitrate to ammonia in two steps. The first step requires nitrate reductase, a nitrate-inducible enzyme. When seedlings of squash ( Cucurbita maxima L.) were treated with nitrate, both nitrate reductase activity and protein were induced in the cotyledons.
N M, Crawford, W H, Campbell, R W, Davis
openaire   +2 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

The genome of the insecticidal Chromobacterium subtsugae PRAA4-1 and its comparison with that of Chromobacterium violaceum ATCC 12472

Genomics Data, 2016
The genome of Chromobacterium subtsugae strain PRAA4-1, a betaproteobacterium producing insecticidal compounds, was sequenced and compared with the genome of C. violaceum ATCC 12472. The genome of C.
Michael B. Blackburn, Michael E. Sparks, Dawn E. Gundersen-Rindal   +2 more
doaj   +1 more source

Effect of pH on the denitrification proteome of the soil bacterium Paracoccus denitrificans PD1222

Scientific Reports, 2021
Denitrification is a respiratory process by which nitrate is reduced to dinitrogen. Incomplete denitrification results in the emission of the greenhouse gas nitrous oxide and this is potentiated in acidic soils, which display reduced denitrification ...
Alfonso Olaya-Abril, Jesús Hidalgo-Carrillo, Víctor M. Luque-Almagro, Carlos Fuentes-Almagro, Francisco J. Urbano, Conrado Moreno-Vivián, David J. Richardson, María Dolores Roldán   +7 more
doaj   +1 more source

Resolving the contributions of the membrane-bound and periplasmic nitrate reductase systems to nitric oxide and nitrous oxide production in Salmonella enterica serovar Typhimurium [PDF]

, 2011
The production of cytotoxic nitric oxide (NO) and conversion into the neuropharmacological agent and potent greenhouse gas nitrous oxide (N2O) is linked with anoxic nitrate catabolism by Salmonella enterica serovar Typhimurium.
Anderson, Anke Arkenberg, Barth, Bleakley, Bodenmiller, Burlat, Carl Harrington, Clarke, Cole, Corinne Appia-Ayme, Costa, Daniela Hensen, Datsenko, David J. Richardson, Elizabeth Baggs, Fersht, Filenko, Gary Rowley, Gilberthorpe, Gilberthorpe, Heather Felgate, Hoiseth, Ji, Jia, Julea N. Butt, Karen Prior, Kim, Mellies, Metheringham, Mills, Nicholas, Poock, Pope, Potter, Potter, Richardson, Sarah J. Field, Satoh, Simon, Smith, Smith, Spiro, Spiro, Stewart, Stewart, Stewart, Stewart, van Riet, van Wonderen, Wang, Weiss   +50 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Complete Circular Genome Sequence and Temperature Independent Adaptation to Anaerobiosis of Listeria weihenstephanensis DSM 24698

Frontiers in Microbiology, 2017
The aim of this study was to analyze the adaptation of the environmental Listeria weihenstephanensis DSM 24698 to anaerobiosis. The complete circular genome sequence of this species is reported and the adaptation of L.
Elena Ferrari, Elena Ferrari, Mathias C. Walter, Christopher Huptas, Christopher Huptas, Siegfried Scherer, Siegfried Scherer, Stefanie Müller-Herbst, Stefanie Müller-Herbst   +8 more
doaj   +1 more source