Results 51 to 60 of about 2,342 (296)

The effect of EU derogation strategies on the compliance costs of the nitrate directive

Science of The Total Environment, 2012
Within the framework of the nitrate directive, member states have the opportunity to apply for derogation, i.e. increasing fertilisation standards under certain conditions. Several EU regions have utilised this opportunity, but each in a different way, resulting in six very different derogation policies within the EU in 2009.
Van der Straeten, Bart, Buysse, Jeroen, Nolte, Stephan, Lauwers, Ludwig H., Claeys, Dakerlia, Van Huylenbroeck, Guido   +5 more
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Changes in the Physicochemical Parameters of Surface Water Over a Period of 35 Years

Journal of Sustainable Development of Energy, Water and Environment Systems
The research was based on the change in physical and chemical parameters of surface water over 35 years. Surface water (river) flows in a sensitive area according to the Nitrate Directive.
Lovorka Gotal Dmitrovic, Darijo Čerepinko   +1 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The need for flexibility and differentiation in the protection of vulnerable areas in EU envrionmental law: the implementation of the nitrates directive in the Netherlands

, 2011
The Nitrates Directive (91/676/EEC) offers EU Member States the unique choice to apply the nitrate regime in either designated areas or on their entire territory.
Environmental Governance, Zwart, K.B., Rijswick, H.F.M.W., De weg naar duurzaamheid: veerkracht, complexiteit en conflictmanagement in het omgevingsrecht, Driessen, P.P.J., UU LEG LAW Landelijke Onderzoekschool Ius Commune, Afd Staats-, Bestuursrecht & Rechtstheo., Runhaar, H.A.C., Oenema, O., Section Environmental Governance, van Rijswick, H.F.M.W., Runhaar, H., Keessen, A.M., Schoumans, O.F.   +13 more
core   +1 more source

Towards understanding and directing the nitration of cellulose

Cellulose
Abstract Nitrocellulose is industrially produced from cellulose by treatment with nitric and sulfuric acid. While sulfuric acid is known to catalyse the hydrolysis of cellulose, its effect on nitrated cellulose has not been reported before. Herein we show by gel permeation chromatography that hydrolysis of nitrocellulose derived from cotton ...
Edmund Morris, Colin R. Pulham, Carole A. Morrison   +2 more
openaire   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Evaluation et proposition de révision du deuxième Programme de Gestion Durable de l'Azote en agriculture en Région wallonne (Belgique) [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2010
Evaluation and revision proposal of the second Action Programme in Walloon Region (Belgium). In accordance with the Nitrates Directive, the second “Durable Nitrogen Management Plan” (PGDA) will be reviewed in 2010.
Vandenberghe C., Benoît J., Deneufbourg M., Destain JP., De Toffoli M., Dufrasne I., Fonder N., Heens B., Hennart S., Lambert S., Marcoen J.M.   +10 more
doaj  

SUBSTANTIATION OF THRESHOLD VALUES OF HYDROCHEMICAL CHARACTERISTICS OF THE PIVDENNYI BUH RIV-ER WATER QUALITY ACCORDING TO THE EU WATER FRAMEWORK DIRECTIVE

Геохімія техногенезу, 2020
According to the results of four-year monitoring studies of the Southern Buh River above and below the Alexander Reservoir, the threshold values have been substantiated for 19 hydrochemical indices of water quality.
Shkapenko V., Buzhuk L., Zoludenko O., Fomina T., Vashchenko N., Zelak O., Litvinenko U.   +6 more
doaj   +1 more source