Thermal Risk Evaluation of the Fluorobenzotriazolone Nitration Process [PDF]
MoleculesThis paper introduces the nitration process of obtaining the synthetic intermediate 1-(2-chloro-4-fluoro-5-nitrobenzene)-4-difluoromethyl-4,5-dihydro-3-methyl-1,2,4-triazol-5(1H)-one of pyraclostrobin using raw materials fluorobenzotriazolone, fuming ...
Yingxia Sheng +4 more
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Continuous-flow-enabled intensification in nitration processes: a review of technological developments and practical applications over the past decade [PDF]
Beilstein Journal of Organic ChemistryFlow chemistry technology has demonstrated significant potential in advancing the green transformation of the chemical industry while enhancing inherent process safety.
Feng Zhou +6 more
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Resveratrol relieves myocardial ischemia–reperfusion injury through inhibiting AKT nitration modification [PDF]
Redox ReportObjective The aim of this study was to clarify whether Protein kinase B (PKB)/AKT is nitrated in myocardial ischemia and reperfusion injury (MIRI) resveratrol (RSV)’s protective effect during this process.Methods We blocked blood flow of the left ...
Lei Li +7 more
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Protein Tyrosine Nitration in Plant Nitric Oxide Signaling
Frontiers in Plant Science, 2022 Nitric oxide (NO), which is ubiquitously present in living organisms, regulates many developmental and stress-activated processes in plants. Regulatory effects exerted by NO lies mostly in its chemical reactivity as a free radical.
José León
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A pilot study on nitration/dysfunction of NK1 segment of myogenic stem cell activator HGF
Biochemistry and Biophysics Reports, 2022 Protein tyrosine residue (Y) nitration, a post-translational chemical-modification mode, has been associated with changes in protein activity and function; hence the accumulation of specific nitrated proteins in tissues may be used to monitor the onset ...
Alaa Elgaabari +12 more
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Nitrate and periplasmic nitrate reductases [PDF]
Chem. Soc. Rev., 2014 The nitrate anion is a simple, abundant and relatively stable species, yet plays a significant role in global cycling of nitrogen, global climate change, and human health. Although it has been known for quite some time that nitrate is an important species environmentally, recent studies have identified potential medical applications.
Courtney, Sparacino-Watkins +2 more
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Redox Biology, 2021 Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy.
Ting Wang +10 more
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Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity
Microbiology Spectrum, 2022 Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin +6 more
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Metal- and acid-free, TBN-mediated direct CH nitration of arenes
Journal of Saudi Chemical Society, 2019 A metal-free, acid-free, direct and eco-friendly nitration methodology has been developed. A tert-butyl nitrite efficiently promotes the direct CH nitration of electron-rich arenes with good to excellent yields and regioselectivities.
Guangqiang Xu +4 more
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Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with “Slow-Heating” Tandem Mass Spectrometry Methods [PDF]
, 2010 Tyrosine nitration in proteins is an important post-translational modification (PTM) linked to various pathological conditions. When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) methods provide unique tools to locate the ...
Cooper, Helen J. +2 more
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