Resveratrol relieves myocardial ischemia–reperfusion injury through inhibiting AKT nitration modification [PDF]
Objective The aim of this study was to clarify whether Protein kinase B (PKB)/AKT is nitrated in myocardial ischemia and reperfusion injury (MIRI) resveratrol (RSV)’s protective effect during this process.Methods We blocked blood flow of the left ...
Lei Li+7 more
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Selective nitration of Hsp90 acts as a metabolic switch promoting tumor cell proliferation [PDF]
Tumors develop in an oxidative environment characterized by peroxynitrite production and downstream protein tyrosine (Y) nitration. We showed that tyrosine nitration supports schwannoma cell proliferation and regulates cell metabolism in the inheritable ...
Isabelle E. Logan+12 more
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Oligomerization and tyrosine nitration enhance the allergenic potential of the birch and grass pollen allergens Bet v 1 and Phl p 5 [PDF]
Protein modifications such as oligomerization and tyrosine nitration alter the immune response to allergens and may contribute to the increasing prevalence of allergic diseases.
Janine Fröhlich-Nowoisky+4 more
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Homogeneous continuous flow nitration of O-methylisouronium sulfate and its optimization by kinetic modeling [PDF]
Nitration of O-methylisouronium sulfate under mixed acid conditions gives O-methyl-N-nitroisourea, a key intermediate of neonicotinoid insecticides with high application value.
Jiapeng Guo, Weike Su, An Su
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Protein Tyrosine Nitration in Plant Nitric Oxide Signaling
Nitric oxide (NO), which is ubiquitously present in living organisms, regulates many developmental and stress-activated processes in plants. Regulatory effects exerted by NO lies mostly in its chemical reactivity as a free radical.
José León
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Nitrate and periplasmic nitrate reductases [PDF]
The nitrate anion is a simple, abundant and relatively stable species, yet plays a significant role in global cycling of nitrogen, global climate change, and human health. Although it has been known for quite some time that nitrate is an important species environmentally, recent studies have identified potential medical applications.
Courtney Sparacino-Watkins+2 more
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Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity
Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin+6 more
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Achalasia is a disease that impairs oesophageal motility. Though nitrates have been used to treat achalasia for a long time, the effectiveness of nitrates for achalasia is still controversial.To quantify short-term and long-term effects of nitrate therapy in patients with achalasia.Trials were identified by searching the Cochrane Controlled Trials ...
Elizabeth Gardener+2 more
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Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells. [PDF]
Nitration of pollen derived allergens can occur by NO(2) and ozone in polluted air and it has already been shown that nitrated major birch (Betula verrucosa) pollen allergen Bet v 1.0101 (Bet v 1) exhibits an increased potency to trigger an immune ...
Anette C Karle+8 more
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The asymmetric unit of the title salt [systematic name: 2-(3,4-dihydroxyphenyl)ethanaminium nitrate], C8H12NO2+·NO3−, contains two independent cations and two independent nitrate anions. The crystal structure consists of discrete nitrate ions stacked in layers parallel to (010).
Sofian Gatfaoui+3 more
openaire +5 more sources