Results 11 to 20 of about 16,997 (260)
Nitrate and periplasmic nitrate reductases [PDF]
The nitrate anion is a simple, abundant and relatively stable species, yet plays a significant role in global cycling of nitrogen, global climate change, and human health. Although it has been known for quite some time that nitrate is an important species environmentally, recent studies have identified potential medical applications.
Courtney, Sparacino-Watkins +2 more
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Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy.
Ting Wang +10 more
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Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity
Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin +6 more
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Metal- and acid-free, TBN-mediated direct CH nitration of arenes
A metal-free, acid-free, direct and eco-friendly nitration methodology has been developed. A tert-butyl nitrite efficiently promotes the direct CH nitration of electron-rich arenes with good to excellent yields and regioselectivities.
Guangqiang Xu +4 more
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Tyrosine nitration in prostaglandin H2 synthase
In this study, we investigated the effects of various nitrogen oxide (NOx) species on the extent of prostaglandin H2 synthase-1 (PGHS-1) nitration in purified protein and in vascular smooth muscle cells.
Ruba S. Deeb +5 more
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DeepNitro: Prediction of Protein Nitration and Nitrosylation Sites by Deep Learning
Protein nitration and nitrosylation are essential post-translational modifications (PTMs) involved in many fundamental cellular processes. Recent studies have revealed that excessive levels of nitration and nitrosylation in some critical proteins are ...
Yubin Xie +10 more
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Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells. [PDF]
Nitration of pollen derived allergens can occur by NO(2) and ozone in polluted air and it has already been shown that nitrated major birch (Betula verrucosa) pollen allergen Bet v 1.0101 (Bet v 1) exhibits an increased potency to trigger an immune ...
Anette C Karle +8 more
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Nitrate or not nitrate. That is the question
A recommendation of: Legay Nicolas, Grassein Fabrice, Arnoldi Cindy, Segura Raphael, Laine Philippe, Lavorel Sandra, Clement Jean-Christophe Studies of NH4+ and NO3- uptake ability of subalpine plants and resource-use strategy identified by their functional traits 10.1101 ...
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Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration
In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide (O2â¢-) and nitric oxide (â¢NO). This process is in competition with
Silvina Bartesaghi, Rafael Radi
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Aminoethyl nitrate – the novel super nitrate? [PDF]
Long‐term use of most organic nitrates is limited by development of tolerance, induction of oxidative stress and endothelial dysfunction. In this issue of the BJP, Schuhmacher et al. characterized a novel class of organic nitrates with amino moieties (aminoalkyl nitrates).
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