Results 11 to 20 of about 432,709 (333)
Protein Tyrosine Nitration in Plant Nitric Oxide Signaling
Frontiers in Plant Science, 2022 Nitric oxide (NO), which is ubiquitously present in living organisms, regulates many developmental and stress-activated processes in plants. Regulatory effects exerted by NO lies mostly in its chemical reactivity as a free radical.
José León
doaj +1 more source
A pilot study on nitration/dysfunction of NK1 segment of myogenic stem cell activator HGF
Biochemistry and Biophysics Reports, 2022 Protein tyrosine residue (Y) nitration, a post-translational chemical-modification mode, has been associated with changes in protein activity and function; hence the accumulation of specific nitrated proteins in tissues may be used to monitor the onset ...
Alaa Elgaabari +12 more
doaj +1 more source
Nitrate and periplasmic nitrate reductases [PDF]
Chem. Soc. Rev., 2014 The nitrate anion is a simple, abundant and relatively stable species, yet plays a significant role in global cycling of nitrogen, global climate change, and human health. Although it has been known for quite some time that nitrate is an important species environmentally, recent studies have identified potential medical applications.
Courtney, Sparacino-Watkins +2 more
openaire +2 more sources
Redox Biology, 2021 Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy.
Ting Wang +10 more
doaj +1 more source
Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity
Microbiology Spectrum, 2022 Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin +6 more
doaj +1 more source
Metal- and acid-free, TBN-mediated direct CH nitration of arenes
Journal of Saudi Chemical Society, 2019 A metal-free, acid-free, direct and eco-friendly nitration methodology has been developed. A tert-butyl nitrite efficiently promotes the direct CH nitration of electron-rich arenes with good to excellent yields and regioselectivities.
Guangqiang Xu +4 more
doaj +1 more source
Bidimensional Tandem Mass Spectrometry for Selective Identification of Nitration Sites in Proteins. [PDF]
, 2007 Nitration of protein tyrosine residues is very often regarded as a molecular signal of peroxynitrite formation during development, oxidative stress, and aging.
AMORESANO, ANGELA +4 more
core +1 more source
Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging [PDF]
, 2020 Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid β (Aβ) plays a crucial role in Alzheimer’s disease.
Fan, Lampson M. +4 more
core +2 more sources
Aromatic nitrations by mixed acid. Slow liquid-liquid reaction regime [PDF]
, 1995 Aromatic nitrations by mixed acid have been selected as a specific case of a heterogeneous liquid-liquid reaction. An extensive experimental programme has been followed using adiabatic and heat-flow calorimetry and pilot reactor experiments, supported by
Alos, M.A. +6 more
core +3 more sources
Acta Crystallographica Section E Structure Reports Online, 2012 In the title mol-ecular salt (systematic name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth-yl}-9-hy-droxy-2-methyl-1,6,7,8,9,9a-hexa-hydro-pyrido[1,2-a]pyrimidin-4-one nitrate), C(23)H(29)FN(4)O(3) (+)·NO(3) (-), the piperidine ring displays a chair conformation and its N atom is protonated; the N-H bond is in an axial orientation.
Jingshui Ge, Yang-Hui Luo
openaire +3 more sources