Striatal neuroinflammation promotes parkinsonism in rats [PDF]
, 2008 The specific role of neuroinflammation in the pathogenesis of Parkinson's disease remains to be fully elucidated. By infusing lipopolysaccharide (LPS) into the striatum, we investigated the effect of neuroinflammation on the dopamine nigrostriatal ...
Don Gash +9 more
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Cytochrome c signalosome in mitochondria [PDF]
, 2011 Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome
Díaz Moreno, Irene +3 more
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DeepNitro: Prediction of Protein Nitration and Nitrosylation Sites by Deep Learning
Genomics, Proteomics & Bioinformatics, 2018 Protein nitration and nitrosylation are essential post-translational modifications (PTMs) involved in many fundamental cellular processes. Recent studies have revealed that excessive levels of nitration and nitrosylation in some critical proteins are ...
Yubin Xie +10 more
doaj +1 more source
Frontiers in Immunology, 2019 Amylase trypsin inhibitors (ATI) can be found in all gluten containing cereals and are, therefore, ingredient of basic foods like bread or pasta. In the gut ATI can mediate innate immunity via activation of the Toll-like receptor 4 (TLR4) on immune cells
Kira Ziegler +12 more
doaj +1 more source
Atmospheric chemistry of bioaerosols: heterogeneous and multiphase reactions with atmospheric oxidants and other trace gases. [PDF]
, 2016 Advances in analytical techniques and instrumentation have now established methods for detecting, quantifying, and identifying the chemical and microbial constituents of particulate matter in the atmosphere.
Estillore, Armando D +2 more
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Acta Crystallographica Section E Structure Reports Online, 2014 The asymmetric unit of the title salt [systematic name: 2-(3,4-dihydroxyphenyl)ethanaminium nitrate], C8H12NO2+·NO3−, contains two independent cations and two independent nitrate anions. The crystal structure consists of discrete nitrate ions stacked in layers parallel to (010).
Sofian Gatfaoui +3 more
openaire +3 more sources
Heterogeneous reactions of particulate matter-bound PAHs and NPAHs with NO3/N2O5, OH radicals, and O3 under simulated long-range atmospheric transport conditions: reactivity and mutagenicity. [PDF]
, 2014 The heterogeneous reactions of ambient particulate matter (PM)-bound polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO3/N2O5, OH radicals, and O3 were studied in a laboratory photochemical chamber. Ambient PM2.5 and PM10 samples were
Arey, Janet +8 more
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Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration
Redox Biology, 2018 In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide (O2â¢-) and nitric oxide (â¢NO). This process is in competition with
Silvina Bartesaghi, Rafael Radi
doaj +1 more source
Antioxidant-Conjugated Peptide Attenuated Metabolic Reprogramming in Pulmonary Hypertension
Antioxidants, 2020 Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary disorder instigated by pulmonary vascular cell proliferation. Activation of Akt was previously reported to promote vascular remodeling. Also, the irreversible nitration of Y350 residue in
Mathews Valuparampil Varghese +6 more
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Enrichment and characterization of a bacteria consortium capable of heterotrophic nitrification and aerobic denitrification at low temperature [PDF]
, 2013 Nitrogen removal in wastewater treatment plants is usually severely inhibited under cold temperature. The present study proposes bioaugmentation using psychrotolerant heterotrophic nitrification-aerobic denitrification consortium to enhance nitrogen ...
Borthwick, Alistair G. L. +3 more
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