Results 11 to 20 of about 6,305 (154)

The Incidence of Benzodiazepine and Benzodiazepine-Related Drug Use in People With and Without Parkinson's Disease-A Nationwide Cohort Study. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Background Non‐motor symptoms of Parkinson's disease (PD), including sleep problems and anxiety, are common and can appear before motor symptoms. Benzodiazepines and benzodiazepine‐related drugs (BZDR) may be used to treat these symptoms, although they are associated with an increased fall risk.
Lonka V, Hartikainen S, Tiihonen M, Koponen M, Tolppanen AM.   +4 more
europepmc   +2 more sources

National Prescribing Trends and Cost Analysis of Antidepressants, Anxiolytics, and Hypnotics in England, 2010-2023. [PDF]

Hum Psychopharmacol
ABSTRACT Introduction We describe prescribing of anxiolytics/hypnotics/antidepressants at an all‐England level between 2010 and 2023, taking account of the influence of the COVID‐19 pandemic‐period. Methods All Primary Care Prescribing data for England for anxiolytics/hypnotics/antidepressant agents taken as tablets or capsules from 1 January 2010 to ...
Stedman M, Davies M, Levy JW, Ingram J, Taylor D, Heald A.   +5 more
europepmc   +2 more sources

Flunitrazepam increases the risk of lamotrigine-induced cutaneous adverse reactions: Combined analysis of medical big data and clinical research. [PDF]

Psychiatry Clin Neurosci
Aim The concomitant use of lamotrigine and valproic acid, a uridine diphosphate (UDP)‐glucuronosyltransferase inhibitor, is a known risk factor for lamotrigine‐induced rashes, which may develop into fatal or severe cutaneous adverse reactions. No drugs other than valproic acid have been shown to increase lamotrigine concentrations in humans by ...
Bando H, Goda M, Nakataki M, Hirai K, Nitta Y, Kawada K, Yoshioka T, Kanda M, Ogawa A, Mukuta-Murakami C, Tsujinaka K, Miyata K, Kitagawa K, Niimura T, Aizawa F, Yagi K, Izawa-Ishizawa Y, Chuma M, Naito T, Tasaki Y, Numata S, Ishizawa K.   +21 more
europepmc   +2 more sources

Effect of Lemborexant-Based Sleep Medication Formulary on Benzodiazepine Reduction and Clinical Outcomes: A Single-Center Retrospective Study. [PDF]

Neuropsychopharmacol Rep
Lemborexant‐based sleep medication formulary reduced benzodiazepine use by 61%, decreased monthly delirium cases and nighttime falls, while shortening hospital stays. This demonstrates that formulary implementation effectively optimizes hypnotic prescribing and improves patient safety outcomes.
Aoki S, Takada K, Sugama T, Kimiwada M, Hoshino T, Koike K, Akada H, Saiga T, Sato S, Shinkai R, Shibata Y, Tomita T.   +11 more
europepmc   +2 more sources

Workplace Drug Testing-Prevalence of Positive Test Results, Most Common Substances, and Importance of Medical Review. [PDF]

Drug Test Anal
Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Helander A, Sparring F.
europepmc   +2 more sources

Prescription Drugs in Pregnancy and Congenital Malformations: A Population-Based Safety Screening Study. [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Background Counseling women who are either pregnant or contemplating pregnancy on their use of prescribed drugs remains a major clinical challenge. Since the thalidomide tragedy in the 1960s, the use of drugs during pregnancy has been subject to widespread concern due to the potential for unwanted effects on the unborn child, notably major ...
Broe A, Pottegård A, Munk-Olsen T, Hallas J, Bliddal M, Petersen I, Damkier P.   +6 more
europepmc   +2 more sources

Nitrazepam

, 2006
europepmc   +2 more sources

NITRAZEPAM IN PREMEDICATION

British Journal of Anaesthesia, 1969
SUMMARY The sedative effects of nitrazepam in a dose of 5 mg and 10 mg have been compared with Mandrax, a combination of methaqualone 250 mg with diphenhydramine 25 mg. Studies were carried out in gynaecological patients undergoing minor surgical operations using the scoring system previously described.
W, Norris, A B, Telfer
openaire   +2 more sources

Nitrazepam--a Safe Hypnotic [PDF]

BMJ, 1969
In 27 patients nitrazepam (Mogadon) taken in acute overdosage produced no untoward effects except drowsiness, even when 80 tablets were consumed. A double-blind trial in patients in general medical wards established that nitrazepam was as effective as butobarbitone as a hypnotic. It is concluded that nitrazepam is a safe and effective hypnotic.
H, Matthew, A T, Proudfoot, R C, Aitken, J A, Raeburn, N, Wright   +4 more
openaire   +2 more sources

A comparison of benzodiazepine and related drug use in Nova Scotia and Australia [PDF]

, 2008
Objective: Benzodiazepines can be a problem if used for long periods, or in at-risk populations, such as the elderly.
AMH, Australian Bureau of Statistics, Australian Government Department of Health and Aging, Clatney L, de Vries T, Goldney RD, Health Canada, Hogan DB, National Prescribing Service, Paris J., Statistics Canada, Tamblyn RM, Tett SE, World Health Organization   +13 more
core   +1 more source