Results 21 to 30 of about 2,926 (168)

Síndrome de West: evolução clínica e eletrencefalográfica de 70 pacientes e resposta ao tratamento com hormônio adrenocorticotrófico, prednisona, vigabatrina, nitrazepam e ácido valpróico West syndrome: clinical and eletroencephalographic follow up of 70 patients and response to the adrenocorticotropic hormone, prednisone, vigabatrin, nitrazepam and valproate

Arquivos de Neuro-Psiquiatria, 2000
Em estudo retrospectivo avaliamos a evolução clínica e eletrencefalográfica das formas criptogênica e sintomática da síndrome de West e analisamos a eficácia do hormônio adrenocorticotrófico, vigabatrina, prednisona, ácido valpróico e nitrazepam no ...
SÉRGIO A. ANTONIUK, ISAC BRUCK, ADRIANE SPESSATTO, SÍLVIA M. HALICK, LAIS R. DE BRUYN, EDUARDO MEISTER, DUILTON DE PAOLA   +6 more
doaj   +1 more source

Supramolecular Solvent Extraction-Gas Chromatography-Tandem Mass Spectrometry for Detection of Benzodiazepines in Urines [PDF]

Fayixue Zazhi, 2021
Objective To establish a method using supramolecular solvent and gas chromatography-tandem mass spectrometry （GC-MS/MS） to analyze 9 benzodiazepines in urines.
LIU Jin-lei, GU Jie, CHEN Li-qin, et al.
doaj   +1 more source

The Mechanism Underlying the Abnormal Expression of α-Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC. [PDF]

CNS Neurosci Ther
The mTOR/GLT‐1 pathway abnormality induces α‐synucleinopathy, contributing to seizures in FCD lesions, which were rescued by treatment with the mTOR inhibitor Rapa or the GLT‐1 enhancer Cef. Intracerebroventricular α‐syn administration attenuated PTZ‐induced seizures in FCD models.
Zhang L, Song JP, Huang J, Liang P, Yang H, Zhang CQ, Shen KF.   +6 more
europepmc   +2 more sources

Comparison of Short- and Long-Acting Benzodiazepine-Receptor Agonists With Different Receptor Selectivity on Motor Coordination and Muscle Relaxation Following Thiopental-Induced Anesthesia in Mice

Journal of Pharmacological Sciences, 2008
In this study, we compared the effects of Type I benzodiazepine receptor–selective agonists (zolpidem, quazepam) and Type I/II non-selective agonists (zopiclone, triazolam, nitrazepam) with either an ultra-short action (zolpidem, zopiclone, triazolam) or
Mamoru Tanaka, Katsuya Suemaru, Shinichi Watanabe, Ranji Cui, Bingjin Li, Hiroaki Araki   +5 more
doaj   +1 more source

Espasmos em flexão: estudo clínico longitudinal de pacientes tratados com Nitrazepam (mogadon)

Arquivos de Neuro-Psiquiatria, 1970
O tratamento foi satisfatório em 11 dos 12 pacientes com espasmos em flexão. Em dois pacientes as crises foram controladas desde o primeiro dia. Em 9 houve redução rápida e significativa da intensidade e da freqüência dos surtos de espasmos em flexão ...
Michel Pierre Lison
doaj   +1 more source

Effect of nitrazepam on nocturnal penile tumescence and rigidity measurement by RigiScan [PDF]

Xin yixue
Objective To investigate whether nitrazepam can increase the accuracy of RigiScan measurement of nocturnal penile tumescence and rigidity （NPTR） by improving the sleep quality of patients.
LIU Yonghui, LIU Zhuojie, ZHANG Yanan, ZANG Zhijun
doaj   +1 more source

Chemoinformatic Study of Benzodiazepines

Applied Medical Informatics, 2023
Benzodiazepines are a type of psychotropic drugs with tranquilizing effect, originally used as ansiolytics. However, benzodiazepines are highly addictive, and a person who abuses them faces a host of symptoms.
Alexandra-Loredana ALMĂŞAN, Corin DUDA-SEIMAN, Edward ŞECLĂMAN, Corina VERNIC   +3 more
doaj  

Toxicity of Nitrazepam (Mogadon)

Pediatric Neurology Briefs, 1987
A pediatric neurologist and his associates at the Children’s Mercy Hospital, Kansas City, report 6 deaths among 80 patients with intractable epilepsy treated with nitrazepam.
J Gordon Millichap
doaj   +1 more source

Genotype-phenotype correlations of STXBP1 pathogenic variants and the treatment choices for STXBP1-related disorders in China

BMC Medical Genomics, 2023
Background We aimed to analyze the genotype-phenotype correlations of STXBP1 pathogenic variants, prognostic factors and the treatment choices in a case-series of STXBP1-related disorders from China.
Miriam Kessi, Baiyu Chen, Li-Dan Shan, Ying Wang, Lifen Yang, Fei Yin, Fang He, Jing Peng, Guoli Wang   +8 more
doaj   +1 more source

A pharmacovigilance approach for assessing the occurrence of suicide-related events induced by antiepileptic drugs using the Japanese adverse drug event report database

Frontiers in Psychiatry, 2023
Increased suicidality after antiepileptic drug (AED) treatment remains controversial. This study aimed to investigate the occurrence of suicide-related events (SREs) in Japan.
Takenao Koseki, Mikako Horie, Satomi Kumazawa, Tetsuo Nakabayashi, Shigeki Yamada   +4 more
doaj   +1 more source