Utilizing the batch Diazotization coupling reaction and the cloud point extraction kinetic spectrophotometric method, trace and Ultra trace amounts from reducing Nitrazepam and Clonazepam were evaluated by way of using 2,5-dimethoxyaniline as a new ...
Mahdi Muna Iskandar +1 more
doaj +2 more sources
Spectrophotometric Determination Of Nitrazepam And Dapson Using Vanillin Reagent in Pharmaceutical Preparations [PDF]
A simple, sensitive and selective spectrophotometric method is described for the determination of dapson and nitrazepam in bulk drug and in dosage forms using vanillin as the chromogenic agent.
Maha Al-Obaidi +2 more
doaj +2 more sources
Spectrophotometric Estimation of Nitrazepam in Pure and in Pharmaceutical Preparations
Three simple, sensitive, accurate, and rapid visible spectrophotometric methods (A, B, and C) have been developed for the estimation of nitrazepam in both pure and in pharmaceutical preparations.
Hemavathi Nagaraju Deepakumari +1 more
doaj +2 more sources
Comparative effects of hypnotic agents on sleep architecture and respiratory outcomes in obstructive sleep apnea: A systematic review and network meta-analysis. [PDF]
Aim This network meta‐analysis of randomized controlled trials (RCTs) aimed to investigate which hypnotics are associated with the most favorable sleep architecture and respiratory outcomes in adults with obstructive sleep apnea. Methods Primary outcomes included total sleep time (TST) and apnea–hypopnea index (AHI) during TST.
Kishi T +6 more
europepmc +2 more sources
Long-Term Trends in Prescribing of Etizolam for Hypnotic Use in a Japanese University Hospital. [PDF]
ABSTRACT Objectives Etizolam is a short‐acting thienodiazepine widely prescribed for anxiety and insomnia despite increasing concerns regarding dependence and guideline recommendations limiting long‐term benzodiazepine use. This study examined long‐term prescribing trends of etizolam compared with benzodiazepine and non‐benzodiazepine hypnotics ...
Nakao M +3 more
europepmc +2 more sources
Effects of Repeated Smoking and Quitting Cigarettes on Plasma Concentrations of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in a Japanese Patient With Schizophrenia. [PDF]
In a Japanese patient with schizophrenia, the effects of repeated smoking and quitting cigarettes on plasma concentrations of clozapine (CLZ) and its major metabolites, N‐desmethyl clozapine (NCLZ) and N‐oxide clozapine (OCLZ), were shown to be reproducible. ABSTRACT Clozapine (CLZ) is used for treatment‐resistant schizophrenia.
Ikawa K +3 more
europepmc +2 more sources
Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open-label prospective study. [PDF]
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Perulli M +12 more
europepmc +2 more sources
Electrochemical detection of nitrazepam using leaf-like graphitic carbon nitride nanosheets
Benzodiazepines like nitrazepam are extensively used, both as prescribed medications and as illicit drug substitutes, and therefore detection is of prime importance.
Mohd Imran +7 more
semanticscholar +1 more source
Two benzodiazepine type drugs, that is, nitrazepam and 7-aminonitrazepam, were studied at the electrified liquid-liquid interface (eLLI). Both drugs are illicit and act sedative in the human body and moreover are used as date rape drugs. Existence of the
Paweł Stelmaszczyk +5 more
semanticscholar +1 more source
Emerging contaminants such as pharmaceutical compounds offer potential hazards to the aquatic environment and human health. In this paper, the adsorptive removal of the drug Nitrazepam from water was investigated for the first time using biochar ...
M. Nazal, D. Rao, Nabeel Abuzaid
semanticscholar +1 more source

