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Nitric Oxide

Seminars in Pediatric Infectious Diseases, 2006
Nitric oxide (NO) is a gas that is involved in many biologic processes. It is synthesized, by the NO synthases. The synthesis of NO by vascular endothelium is responsible for the vasodilator tone. In the central nervous system, it is a neurotransmitter, involved in the formation of memory; in the periphery, some nerves operate through NO-dependent ...
Xiomara, Garcia, Fernando, Stein
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Nitric oxide

The International Journal of Biochemistry & Cell Biology, 1997
Nitric oxide (NO) is a gas with diverse biological activities produced from arginine by NO synthases. It is capable of interacting with a number of molecules, most notably superoxide, forming peroxynitrite, which, in turn, can mediate bactericidal or cytotoxic reactions.
R A, Robbins, M B, Grisham
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Nitric Oxide and Angiogenesis

Journal of Neuro-Oncology, 2000
The steps required for new vessel growth are biologically complex and require coordinate regulation of contributing components, including modifications of cell--cell interactions, proliferation and migration of endothelial cells and matrix degradation.
Ziche, Marina, Morbidelli, Lucia
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Nitric Oxide and Atherosclerosis

Nitric Oxide, 2001
Endothelial dysfunction has been shown in a wide range of vascular disorders including atherosclerosis and related diseases. Here, we examine and address the complex relationship among nitric oxide (NO)-mediated pathways and atherogenesis. In view of the numerous pathophysiological actions of NO, abnormalities could potentially occur at many sites: (a)
NAPOLI, Claudio, IGNARRO LJ
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Nitric oxide

European Journal of Pediatrics, 1994
Although persistent pulmonary hypertension of the newborn (PPHN) has been considered to be a relatively rare condition, there is increasing evidence that pulmonary vasoconstriction is a common finding in moderate and severe respiratory distress syndrome.
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Multimodality imaging of nitric oxide and nitric oxide synthases

Free Radical Biology and Medicine, 2009
Nitric oxide (NO) and NO synthases (NOSs) are crucial factors in many pathophysiological processes such as inflammation, vascular/neurological function, and many types of cancer. Noninvasive imaging of NO or NOS can provide new insights in understanding these diseases and facilitate the development of novel therapeutic strategies.
Hao, Hong, Jiangtao, Sun, Weibo, Cai
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Detection of nitric oxide and nitric oxide synthases in psoriasis

Archives of Dermatological Research, 1998
Biopsies from psoriasis lesions and clinically uninvolved skin of eight patients and five normal subjects were studied by immunocytochemistry with computerized image analysis for the presence of endothelial, neuronal and inducible isoforms of nitric oxide synthase.
A D, Ormerod   +6 more
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Nitric oxide and nitric oxide synthase activity in plants

Phytochemistry, 2004
Research on NO in plants has gained considerable attention in recent years mainly due to its function in plant growth and development and as a key signalling molecule in different intracellular processes in plants. The NO emission from plants is known since the 1970s, and now there is abundant information on the multiple effects of exogenously applied ...
Luis A, del Río   +2 more
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Nitric Oxide

The American Journal of the Medical Sciences, 1993
Nitric oxide is a newly discovered gas that mediates communication between adjacent cells and signals inside cells. Defects in the nitric oxide signalling cascade have been found in patients with systemic hypertension, pulmonary hypertension, and coronary artery disease. High concentrations of nitric oxide are cytotoxic. Over-production of nitric oxide
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Sepsis and Nitric Oxide

1996
Sepsis or the septic syndrome is the number one cause of mortality in todays intensive care. Overall mortality of sepsis is estimated to be 40 to 60% and when shock or organ failure is present mortality rate is even higher despite recent progress in antibiotic and vasopressor therapy (Bone et al. 1991).
Avontuur, J, Bruining, HA, Ince, Can
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