Results 61 to 70 of about 3,846,165 (408)

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Nitric oxide: an endogenous modulator of leukocyte adhesion.

Proceedings of the National Academy of Sciences of the United States of America, 1991
The objective of this study was to determine whether endogenous nitric oxide (NO) inhibits leukocyte adhesion to vascular endothelium. This was accomplished by superfusing a cat mesenteric preparation with inhibitors of NO production, NG-monomethyl-L ...
P. Kubes, M. Suzuki, D. Granger
semanticscholar   +1 more source

Mitigation of Cracks in High‐Performance Nickel‐Based Superalloys in Powder Bed Fusion Laser Beam of Metals Using a Metal Matrix Composite Approach

Advanced Engineering Materials, EarlyView.
High‐performance nickel‐based superalloys are often not processible in additive manufacturing (AM) due to hot cracking. The findings in this manuscript propose an efficient method to mitigate cracking and enhance mechanical properties of these alloys by producing a metal matrix composite, contributing to the material and process perspective of the AM ...
Klaus Büßenschütt, Maël Pontoreau, Christian Haase, Johannes‐Henrich Schleifenbaum   +3 more
wiley   +1 more source

Nitric Oxide Donors

Proceedings of the Society for Experimental Biology and Medicine, 2000
Abstract.Nitric oxide (NO) donors are pharmacologically active substances that release NOin vivoorin vitro. NO has a variety of functions such as the release of prostanoids, inhibition of platelet aggregation, effect on angiogenesis, and production of oxygen free radicals.
Tadahiko Yamamoto, Richard J. Bing
openaire   +2 more sources

Therapeutic strategies to address neuronal nitric oxide synthase deficiency and the loss of nitric oxide bioavailability in Duchenne Muscular Dystrophy. [PDF]

, 2017
Duchenne Muscular Dystrophy is a rare and fatal neuromuscular disease in which the absence of dystrophin from the muscle membrane induces a secondary loss of neuronal nitric oxide synthase and the muscles capacity for endogenous nitric oxide synthesis ...
Hayes, Alan, Rybalka, Emma, Timpani, Cara   +2 more
core   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

Nitric oxide synthases in mammals.

Biochemical Journal, 1994
Nitric oxide is an inorganic free radical gas, of formula *N=O (abbreviated as NO). The discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L-arginine as a transcellular signal [1-4] was initially received by most ...
Richard Graham Knowles, S. Moncada
semanticscholar   +1 more source

Detection of nitric oxide pollution [PDF]

, 1973
Studies of absorption spectra enhancement of certain atomic and molecular species inserter in dye-laser cavities have indicated that nitric oxide can be determined at low concentrations.
Chackerian, C., Jr., Weisbach, M. F.
core   +1 more source

Inhibition of NOS- like activity in maize alters the expression of genes involved in H2O2 scavenging and glycine betaine biosynthesis [PDF]

, 2018
Nitric oxide synthase-like activity contributes to the production of nitric oxide in plants, which controls plant responses to stress. This study investigates if changes in ascorbate peroxidase enzymatic activity and glycine betaine content in response
A Deisseroth, A Sakamoto, A Uchida, A Untergasser, C Garcia-Mata, C Lindermayr, D Clarke, D Procházková, D Rhodes, D Wendehenne, E Baudouin, EA Weretilnyk, G Perrière, HI Aebi, II Ozyigit, J Leach, JC Begara-Morales, K Yamane, KF McCue, KJL Livak, L Zhang, LA Rio Del, M Ashraf, M Cueto, M Delldonne, M Ishitani, M Yu, MA Larkin, MG Zhao, MH Siddiqui, MV Beligni, N Ludidi, RD Allen, S Ullah, SA Anjum, SAH Mackerness, SJ Neill, T Nakamura, TE Mishina, V Velikova, W Woodbury, Y Guo, Y Zhang, YJ Liu, YY Leshem   +44 more
core   +2 more sources