Results 91 to 100 of about 344,134 (303)

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]

, 2015
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor, Comeau, Jason, DiMuzio, Paul J., Faul, Elizabeth J, Fernandez, Sarah, Ferroni, Matthew, McIlhenny, Stephen, Policha, Aleksandra, Shapiro, Irving, Tulenko, Thomas, Zhang, Ping   +10 more
core   +2 more sources

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Is there a relationship between endothelial nitric oxide synthase gene polymorphisms and ankylosing spondylitis?

Clinics, 2013
OBJECTIVE: Nitric oxide is produced by endothelial nitric oxide synthase, and its production can be influenced by polymorphisms of the endothelial nitric oxide synthase gene.
Ismail Sari, Yusuf Ziya Igci, Gercek Can, Ali Taylan, Dilek Solmaz, Bulent Gogebakan, Servet Akar, Zeynep Eslik, Giray Bozkaya, Nurullah Akkoc   +9 more
doaj  

Investigations into potential extrasynaptic communication between the dopaminergic and nitrergic systems

Frontiers in Physiology, 2012
Nitric oxide is unconstrained by cell membranes and can therefore act along a broad distance as a volume transmitter. Spillover of nitric oxide between neurons may have a major impact on central nervous system diseases and particularly on ...
Miso eMitkovski, Fernando Eduardo Padovan-Neto, Rita eRaisman-Vozari, Rita eRaisman-Vozari, Laure eGinestet, Laure eGinestet, Celia eDa-Silva, Elaine eDel Bel, Elaine eDel Bel   +8 more
doaj   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Neuronal and inducible nitric oxide synthase upregulation in the rat medial prefrontal cortex following acute restraint stress: A dataset

Data in Brief, 2016
This data article provides additional evidence on gene expression changes in the neuronal and inducible isoforms of nitric oxide synthase in the medial prefrontal cortex following acute stress.
Jereme G. Spiers, Hsiao-Jou Cortina Chen, Johnny K. Lee, Conrad Sernia, Nickolas A. Lavidis   +4 more
doaj   +1 more source

Blocked dihydropteridines as nitric oxide synthase activators [PDF]

, 2010
It has been shown that 6-acetyl-7,7-dimethyl-5,6,7,8-tetrahydropteridin-4(3H)-one can act as a competent cofactor for the production of nitric oxide by neuronal nitric oxide synthase (nNOS).
Daff, Simon, Gazur, Ben, Gibson, C.L., McInnes, Craig R., Morthala, Raghavendar R., Suckling, C.J.   +5 more
core  

The influence of nitric oxide on perigeniculate GABAergic cell activity in the anaesthetized cat [PDF]

, 1996
[Abstract] We have tested the effect of iontophoretic application of the nitric oxide synthase inhibitor l-nitroarginine on the activity of a population of 53 perigeniculate (PGN) cells, recorded extracellularly in the anaesthetized paralysed cat. In all
Acuña, Carlos, Cudeiro, Javier, Martínez-Conde, Susana, Rivadulla, Casto, Rodríguez, R.   +4 more
core   +2 more sources

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Interaction between cholinergic and nitrergic vasodilation: a novel mechanism of blood pressure control [PDF]

, 2017
Objective: Cholinergic vasodilation has been thought to play little if any role in the regulation of blood pressure in humans. Autonomic denervation potentiates the vasoconstriction evoked by nitric oxide synthase inhibition in humans, but the mechanism ...
Duplain, Hervé, Lepori, Mattia, Nicod, Pascal, Sartori, Claudio, Scherrer, Urs   +4 more
core