Results 11 to 20 of about 462,598 (258)

Tetrahydrobiopterin in nitric oxide synthase [PDF]

open access: yesIUBMB Life, 2013
AbstractSummary: Nitric oxide synthase (NOS) is a critical enzyme for the production of the messenger molecule nitric oxide (NO) from L‐arginine. NOS enzymes require tetrahydrobiopterin as a cofactor for NO synthesis. Besides being one of the few enzymes to use this cofactor, the role of tetrahydrobiopterin in NOS catalytic mechanism is different from ...
J. Tejero, D. Stuehr
semanticscholar   +3 more sources

Nitric Oxide synthases and atrial fibrillation [PDF]

open access: yesFrontiers in Physiology, 2012
Oxidative stress has been implicated in the pathogenesis of atrial fibrillation. There are multiple systems in the myocardium which contribute to redox homeostasis, and loss of homeostasis can result in oxidative stress.
Ingrid M Bonilla   +8 more
doaj   +4 more sources

Neuronal Nitric Oxide Synthase

open access: yes, 2017
Nitric oxide synthase (NOS), a flavo‐hemoprotein, regulates nitric oxide (NO) synthesis that has dual biological activities: as an important signalling molecule in vasodilatation and neurotransmission at low concentrations and at higher concentrations as
Kourosh Masoumeh Arami   +2 more
semanticscholar   +4 more sources

Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase [PDF]

open access: yesClinical and Molecular Hepatology, 2015
The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could be a therapeutic target for liver fibrosis.
Y. Iwakiri
semanticscholar   +5 more sources

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

open access: yesPulmonary Circulation, 2021
The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Matthew S. Douglass   +3 more
doaj   +1 more source

The Effect of Pneumonic Pasteurellosis on Apoptosis and Nitric Oxide Synthase in the Lungs in Calves

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2020
Pneumonic Pasteurellosis (PP) is an infectious disease caused by Pasteurella multocida and Mannheimia haemolytica, mostly observed in cattle, sheep and calves. PP is characterized by fibrinous bronchopneumonia and pleuritis in the lungs.
Orhan Yavuz, Güngör Çağdaş Dinçel
doaj   +1 more source

Nitric oxide in gingival crevicular fluid and nitric oxide synthase expression in the gingiva of patients with sickle cell disease

open access: yesTurkish Journal of Hematology, 2011
OBJECTIVE: This study aimed to biochemically measure the production of nitric oxide in gingival crevicular fluid and immunohistochemically measure the expression of inducible nitric oxide synthase in the gingiva of patients with sickle cell disease ...
Esra Güzeldemir   +4 more
doaj   +3 more sources

Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy

open access: yesNeural Regeneration Research, 2023
Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity, which triggers cell death in various neuropathological diseases, including epilepsy.
Xiao-Xue Xu   +13 more
doaj   +1 more source

Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. [PDF]

open access: yesPLoS ONE, 2014
Spontaneous calcium waves in cardiac myocytes are caused by diastolic sarcoplasmic reticulum release (SR Ca(2+) leak) through ryanodine receptors.
Jerry Curran   +13 more
doaj   +1 more source

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

open access: yesFrontiers in Immunology, 2014
Macrophages play a major role in the immune system, both as antimicrobial effector cells and as immunoregulatory cells, which induce, suppress or modulate adaptive immune responses.
Meera Rath   +4 more
semanticscholar   +1 more source

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