Results 31 to 40 of about 344,134 (303)
Modeling co-operative volume signaling in a plexus of nitric oxide synthase-expressing neurons [PDF]
, 2005 In vertebrate and invertebrate brains, nitric oxide (NO) synthase (NOS) is frequently expressed in extensive meshworks (plexuses) of exceedingly fine fibers.
Husbands, Philip +4 more
core +1 more source
Role of Dietary Polyphenols in the Activity and Expression of Nitric Oxide Synthases: A Review
Antioxidants, 2023 Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually released in numerous organs and tissues. There are mainly three isoforms of the enzyme that produce NO starting from the metabolism of arginine, namely ...
Gabriele Serreli, Monica Deiana
doaj +1 more source
Involvement of Nitric Oxide in Microcirculatory Reactions after Ischemia-Reperfusion of the Rat Urinary Bladder [PDF]
, 2009 Background: Nitric oxide ( NO) plays a role in inflammation. Our aim was to investigate the role of NO in the microcirculatory changes after ischemia-reperfusion (I/R) of the bladder using intravital videomicroscopy (IVM).
Bajory, Z. +4 more
core +2 more sources
Elevated exhaled nitric oxide in allergen-provoked asthma is associated with airway epithelial iNOS.
PLoS ONE, 2014 BackgroundFractional exhaled nitric oxide is elevated in allergen-provoked asthma. The cellular and molecular source of the elevated fractional exhaled nitric oxide is, however, uncertain.ObjectiveTo investigate whether fractional exhaled nitric oxide is
Abraham B Roos +10 more
doaj +1 more source
Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]
, 2016 BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS +6 more
core +1 more source
Forum of Clinical OncologyNeutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) are widely used to assess patient’s outcome in many ...
Zergoun Ahmed Amine +4 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundNitric oxide synthase uncoupling occurs under conditions of oxidative stress modifying the enzyme's function so it generates superoxide rather than nitric oxide.
Toru Hashimoto +10 more
doaj +1 more source
Mammalian nitric oxide synthases
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1999 The nitric oxide (NO) synthase family of enzymes generate NO from L-arginine, which acts as a biologic effector molecule in a broad number of settings. This report summarizes some of the current information regarding NO synthase structure-function, reaction mechanism, control of catalysis, and protein interactions.
openaire +2 more sources
Nitric Oxide Synthase and Oxidative Stress: Regulation of Nitric Oxide Synthase
, 2012 IntroductionIl a été constaté que l'oxyde nitrique joue un rôle important en tant que molécule signal dans de nombreuses parties de l'organisme ainsi qu'en tant que molécule effectrice cytotoxique de la réponse immunitaire non spécifique.L' oxyde nitrique est une fonction très importante à la fois chez les helminthes et les hôtes mammifères.L' oxyde ...
Ehab M. M. Ali, M. Soha, Monwar Tarek
openaire +3 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source