Results 11 to 20 of about 344,134 (303)

Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy

Neural Regeneration Research, 2023
Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity, which triggers cell death in various neuropathological diseases, including epilepsy.
Xiao-Xue Xu, Rui-Xue Shi, Yu Fu, Jia-Lu Wang, Xin Tong, Shi-Qi Zhang, Na Wang, Mei-Xuan Li, Yu Tong, Wei Wang, Miao He, Bing-Yang Liu, Gui-Lan Chen, Feng Guo   +13 more
doaj   +1 more source

Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. [PDF]

PLoS ONE, 2014
Spontaneous calcium waves in cardiac myocytes are caused by diastolic sarcoplasmic reticulum release (SR Ca(2+) leak) through ryanodine receptors.
Jerry Curran, Lifei Tang, Steve R Roof, Sathya Velmurugan, Ashley Millard, Stephen Shonts, Honglan Wang, Demetrio Santiago, Usama Ahmad, Matthew Perryman, Donald M Bers, Peter J Mohler, Mark T Ziolo, Thomas R Shannon   +13 more
doaj   +1 more source

In vitro and in vivo TNFa synthesis modulation by methylguanidine, an uremic catabolyte [PDF]

, 1999
Original article can be found at: http://www.sciencedirect.com/science/journal/00243205 Copyright Elsevier Inc.We have investigated whether methylguanidine (MG), an uremic toxin, modulates the expression of the inducible nitric oxide synthase (iNOS) and ...
Aucella, Berczi, Deakin, Deenitchina, Deschamps-Latscha, Drapier, Garcia-Valdecasas, Garreld, Girndt, Halwachs, Jones, Kawano, Kelly, Mendes-Ribeiro, Meur, Moncada, Orita, Ruetten, Shurtz-Swirski, Sorrentino, Sorrentino, Yokozawa   +21 more
core   +1 more source

The effect of chronic peripheral nesfatin-1 application on blood pressure in normal and chronic restraint stressed rats: Related with circulating level of blood pressure regulators [PDF]

, 2015
Nesfatin is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is involved in the regulation of homeostasis. Although the effects of nesfatin-1 on nutrition have been studied widely in the literature, the mechanisms of ...
Ayada, C., Güçlü, Z., Turgut, Günfer, Turgut, Sebahat   +3 more
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Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy

Cardiovascular Ultrasound, 2006
Background Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with ...
Arslan Erol, Barcin Cem, Sezer Murat, Ozbek Ugur, Ekmekci C Gokhan, Olcay Ayhan, Boztosun Bilal, Nisanci Yilmaz   +7 more
doaj   +1 more source

Inhibition of NOS- like activity in maize alters the expression of genes involved in H2O2 scavenging and glycine betaine biosynthesis [PDF]

, 2018
Nitric oxide synthase-like activity contributes to the production of nitric oxide in plants, which controls plant responses to stress. This study investigates if changes in ascorbate peroxidase enzymatic activity and glycine betaine content in response
A Deisseroth, A Sakamoto, A Uchida, A Untergasser, C Garcia-Mata, C Lindermayr, D Clarke, D Procházková, D Rhodes, D Wendehenne, E Baudouin, EA Weretilnyk, G Perrière, HI Aebi, II Ozyigit, J Leach, JC Begara-Morales, K Yamane, KF McCue, KJL Livak, L Zhang, LA Rio Del, M Ashraf, M Cueto, M Delldonne, M Ishitani, M Yu, MA Larkin, MG Zhao, MH Siddiqui, MV Beligni, N Ludidi, RD Allen, S Ullah, SA Anjum, SAH Mackerness, SJ Neill, T Nakamura, TE Mishina, V Velikova, W Woodbury, Y Guo, Y Zhang, YJ Liu, YY Leshem   +44 more
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ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY

Фармация и фармакология (Пятигорск), 2022
Nitric oxide as a therapeutic approach to the treatment of cardiovascular diseases attracted the attention of researchers at the end of the 19th century.
D. V. Kurkin, E. E. Abrosimova, D. A. Bakulin, N. S. Kovalev, M. A. Dubrovina, A. V. Borisov, A. V. Strygin, E. I. Morkovin, I. N. Tyurenkov   +8 more
doaj   +1 more source

Signaling from blood vessels to CNS axons through nitric oxide [PDF]

, 2006
Brain function is usually perceived as being performed by neurons with the support of glial cells, the network of blood vessels situated nearby serving simply to provide nutrient and to dispose of metabolic waste.
Bartus, K, Dooldeniya, C, Garthwaite, G, Garthwaite, J, Goodwin, D, Kollb-Sielecka, M, Malcolm, D   +6 more
core   +1 more source

Adenosine preconditioning attenuates hepatic reperfusion injury in the rat by preventing the down-regulation of endothelial nitric oxide synthase

BMC Gastroenterology, 2002
Background Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet been investigated. Methods Wistar
Williamson Robin CN, Habib Nagy A, Virlos Ioannis T, Serracino-Inglott Ferdinand, Mathie Robert T   +4 more
doaj   +1 more source

The Expression of Type-1 and Type-2 Nitric Oxide Synthase in Selected Tissues of the Gastrointestinal Tract during Mixed Mycotoxicosis

Toxins, 2013
The aim of the study was to verify the hypothesis that intoxication with low doses of mycotoxins leads to changes in the mRNA expression levels of nitric oxide synthase-1 and nitric oxide synthase-2 genes in tissues of the gastrointestinal tract and the ...
Magdalena Gajęcka, Ewa Stopa, Michał Tarasiuk, Łukasz Zielonka, Maciej Gajęcki   +4 more
doaj   +1 more source