Results 11 to 20 of about 347,268 (305)

Zinc-fortification restores gut nitric oxide without expression of inducible nitric oxide synthase gene in enterotoxigenic E. coli-induced diarrhea in zinc-deficient rats

Scientific African, 2021
Nitric oxide maintains the integrity of the gastric epithelium and is also elevated in diarrheal disease condition. Nitric oxide synthase isoforms (NOS) are responsible for production of nitric oxide (NO) in physiological and pathophysiological ...
Ebuka E. David, Muhammad A. Yameen, Ikechuku O. Igwenyi, Chidinma N. David   +3 more
doaj   +1 more source

Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy

Neural Regeneration Research, 2023
Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity, which triggers cell death in various neuropathological diseases, including epilepsy.
Xiao-Xue Xu, Rui-Xue Shi, Yu Fu, Jia-Lu Wang, Xin Tong, Shi-Qi Zhang, Na Wang, Mei-Xuan Li, Yu Tong, Wei Wang, Miao He, Bing-Yang Liu, Gui-Lan Chen, Feng Guo   +13 more
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Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. [PDF]

PLoS ONE, 2014
Spontaneous calcium waves in cardiac myocytes are caused by diastolic sarcoplasmic reticulum release (SR Ca(2+) leak) through ryanodine receptors.
Jerry Curran, Lifei Tang, Steve R Roof, Sathya Velmurugan, Ashley Millard, Stephen Shonts, Honglan Wang, Demetrio Santiago, Usama Ahmad, Matthew Perryman, Donald M Bers, Peter J Mohler, Mark T Ziolo, Thomas R Shannon   +13 more
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In vitro and in vivo TNFa synthesis modulation by methylguanidine, an uremic catabolyte [PDF]

, 1999
Original article can be found at: http://www.sciencedirect.com/science/journal/00243205 Copyright Elsevier Inc.We have investigated whether methylguanidine (MG), an uremic toxin, modulates the expression of the inducible nitric oxide synthase (iNOS) and ...
Aucella, Berczi, Deakin, Deenitchina, Deschamps-Latscha, Drapier, Garcia-Valdecasas, Garreld, Girndt, Halwachs, Jones, Kawano, Kelly, Mendes-Ribeiro, Meur, Moncada, Orita, Ruetten, Shurtz-Swirski, Sorrentino, Sorrentino, Yokozawa   +21 more
core   +1 more source

Tetrahydrobiopterin in nitric oxide synthase [PDF]

IUBMB Life, 2013
AbstractSummary: Nitric oxide synthase (NOS) is a critical enzyme for the production of the messenger molecule nitric oxide (NO) from L‐arginine. NOS enzymes require tetrahydrobiopterin as a cofactor for NO synthesis. Besides being one of the few enzymes to use this cofactor, the role of tetrahydrobiopterin in NOS catalytic mechanism is different from ...
Jesús, Tejero, Dennis, Stuehr
openaire   +2 more sources

The effect of chronic peripheral nesfatin-1 application on blood pressure in normal and chronic restraint stressed rats: Related with circulating level of blood pressure regulators [PDF]

, 2015
Nesfatin is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is involved in the regulation of homeostasis. Although the effects of nesfatin-1 on nutrition have been studied widely in the literature, the mechanisms of ...
Ayada, C., Güçlü, Z., Turgut, Günfer, Turgut, Sebahat   +3 more
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Nitric oxide and nitric oxide synthase in Huntington's disease [PDF]

Journal of Neuroscience Research, 2001
AbstractNitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function ...
openaire   +2 more sources

Inhibition of NOS- like activity in maize alters the expression of genes involved in H2O2 scavenging and glycine betaine biosynthesis [PDF]

, 2018
Nitric oxide synthase-like activity contributes to the production of nitric oxide in plants, which controls plant responses to stress. This study investigates if changes in ascorbate peroxidase enzymatic activity and glycine betaine content in response
A Deisseroth, A Sakamoto, A Uchida, A Untergasser, C Garcia-Mata, C Lindermayr, D Clarke, D Procházková, D Rhodes, D Wendehenne, E Baudouin, EA Weretilnyk, G Perrière, HI Aebi, II Ozyigit, J Leach, JC Begara-Morales, K Yamane, KF McCue, KJL Livak, L Zhang, LA Rio Del, M Ashraf, M Cueto, M Delldonne, M Ishitani, M Yu, MA Larkin, MG Zhao, MH Siddiqui, MV Beligni, N Ludidi, RD Allen, S Ullah, SA Anjum, SAH Mackerness, SJ Neill, T Nakamura, TE Mishina, V Velikova, W Woodbury, Y Guo, Y Zhang, YJ Liu, YY Leshem   +44 more
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Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy

Cardiovascular Ultrasound, 2006
Background Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with ...
Arslan Erol, Barcin Cem, Sezer Murat, Ozbek Ugur, Ekmekci C Gokhan, Olcay Ayhan, Boztosun Bilal, Nisanci Yilmaz   +7 more
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ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY

Фармация и фармакология (Пятигорск), 2022
Nitric oxide as a therapeutic approach to the treatment of cardiovascular diseases attracted the attention of researchers at the end of the 19th century.
D. V. Kurkin, E. E. Abrosimova, D. A. Bakulin, N. S. Kovalev, M. A. Dubrovina, A. V. Borisov, A. V. Strygin, E. I. Morkovin, I. N. Tyurenkov   +8 more
doaj   +1 more source