Results 231 to 240 of about 200,814 (309)

Trimethylamine N-Oxide (TMAO) Acts as Inhibitor of Endothelial Nitric Oxide Synthase (eNOS) and Hampers NO Production and Acetylcholine-Mediated Vasorelaxation in Rat Aortas. [PDF]

Antioxidants (Basel)
Martelli A, Abate F, Roggia M, Benedetti G, Caradonna E, Calderone V, Tenore GC, Cosconati S, Novellino E, Stornaiuolo M.   +9 more
europepmc   +1 more source

TETRAHYDROBIOPTERIN OXIDATION AND REACTIVE OXYGEN SPECIES CONTRIBUTE TO H2O2-INDUCED ENDOTHELIAL NITRIC OXIDE SYNTHASE DYSFUNCTION

, 2005
Beth Michelle Boulden
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Circular RNA hsa_circ_0099188 regulates inducible nitric oxide synthase and chemokine transcription in macrophages by targeting the hsa-miR-381-3p/PPP3CA and hsa-miR-381-3p/KLF4 pathways in response to 4,4'-methylene diphenyl diisocyanate-glutathione conjugate exposure. [PDF]

Toxicol Sci
Lin CC, Law BF, Hettick JM.
europepmc   +1 more source

Trophoblast expression of kallikrein, bradykinin b2 receptor, and endothelial nitric oxide synthase in normal gestation, preeclampsia and placenta accreta

, 2006
Gloría Valdés, Jenny Corthorn, AA Germain, Cecilia Chacón, Sergio Rey, GX Soto, Isamar Duarte   +6 more
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

RETRACTED: Vaccaro et al. Differential Expression of Nitric Oxide Synthase Isoforms nNOS and iNOS in Patients with Non-Segmental Generalized Vitiligo. <i>Int. J. Mol. Sci.</i> 2017, <i>18</i>, 2533. [PDF]

Int J Mol Sci
Vaccaro M, Irrera N, Cutroneo G, Rizzo G, Vaccaro F, Anastasi GP, Borgia F, Cannavò SP, Altavilla D, Squadrito F.   +9 more
europepmc   +1 more source

Supplementary parenteral arginine corrects hypoargininaemia and rebalances plasma amino acid profiles in very preterm infants receiving parenteral nutrition: A prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Plasma amino acid (AA) profiles in parenteral nutrition (PN)–dependent very preterm infants (VPIs) consistently show overprovision of essential AA (EAA) and arginine deficiency. This may have implications for growth and immune/inflammatory responses.
Frances Callaghan, Laura Burgess, Chandini Menon Premakumar, Diane McCarter, Eva Caamaño Gutièrrez, Daniel B. Hawcutt, Colin Morgan   +6 more
wiley   +1 more source

Phytochemical Analysis, Computational Study, and in vitro Assay of <i>Etlingera elatior</i> Inflorescence Extract Towards Inducible Nitric Oxide Synthase. [PDF]

J Exp Pharmacol
Prayoga DK, Pitaloka DAE, Aulifa DL, Budiman A, Levita J, Jiranusornkul S, Nguyen BP.   +6 more
europepmc   +1 more source

The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease

Prenatal Diagnosis, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman, Mirthe E. M. van der Meijden, Johannes M. P. J. Breur, Raymond Stegeman, Nicolaas J. G. Jansen, Mireille N. Bekker, Manon J. N. L. Benders, Nathalie H. P. Claessens   +7 more
wiley   +1 more source