Results 231 to 240 of about 630,432 (401)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Association of Endothelial Nitric Oxide Synthase Polymorphisms with Clinical Severity in Patients with COVID-19. [PDF]

J Clin Med
İdikut A, Değer İ, Göktaş G, Karahan S, Sarınç S, Köksal D, Babaoğlu MO, Babaoğlu E.   +7 more
europepmc   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

Proceedings of the National Academy of Sciences of the United States of America, 2014
Adrienne L. King, David J. Polhemus, S. Bhushan, H. Otsuka, Kazuhisa Kondo, Chad K. Nicholson, J. Bradley, K. Islam, J. Calvert, Y. Tao, T. Dugas, E. Kelley, J. Elrod, Paul L Huang, Rui Wang, D. Lefer   +15 more
semanticscholar   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

<b>Expression of brain nitric oxide synthase mRNA in various tissues and cultured cells of </b><b>rat </b>

, 1992
Taihei Imai, Yukio Hirata, Fumiaki Marumo   +2 more
openalex   +2 more sources

Functional and Genomic Evidence of L-Arginine-Dependent Bacterial Nitric Oxide Synthase Activity in <i>Paenibacillus nitricinens</i> sp. nov. [PDF]

Biology (Basel)
Saavedra-Tralma D, Gaete A, Merino-Guzmán C, Parada-Ibáñez M, Nájera-de Ferrari F, Jofré-Fernández I.   +5 more
europepmc   +1 more source

Curcuma comosa‐Derived Diarylheptanoid Ameliorates Ulcerative Colitis by Inhibiting JNK/NF‐κB and Activating AMPK/Nrf2 Pathways

Food Frontiers, EarlyView.
In this study, we isolated and investigated the protective effect of 1,7‐diphenyl‐(6E)‐6‐hepten‐3‐ol (DPHP) against ulcerative colitis. Our results demonstrate that DPHP administration effectively alleviates colitis symptoms, inhibits inflammation, and strengthens antioxidant defense mechanisms. A combination of network pharmacology analysis, molecular
Van‐Long Truong, Razanamanana H. G. Rarison, Woo‐Sik Jeong   +2 more
wiley   +1 more source

Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury

, 1994
Wei Wu, Francis J. Liuzzi, Frank P. Schinco, A S Depto, Y. Li, Jessica A. Mong, Ted M. Dawson, S H Snyder   +7 more
openalex   +1 more source

Augmentation of Blood Flow through Cerebral Collaterals by Inhibition of Nitric Oxide Synthase [PDF]

, 1994
Michael G. Muhonen, Donald D. Heistad, Frank M. Faraci, Christopher M. Loftus   +3 more
openalex   +1 more source