Results 271 to 280 of about 200,814 (309)
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Nitric oxide synthases and osteoarthritis
Current Rheumatology Reports, 2007The production of nitric oxide (NO) by chondrocytes is increased in human osteoarthritis. The excessive production of NO inhibits matrix synthesis and promotes its degradation. Furthermore, by reacting with oxidants such as superoxide anion, NO promotes cellular injury and renders the chondrocyte susceptible to cytokine-induced apoptosis.
Jose U, Scher +2 more
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Kidney Mitochondrial Nitric Oxide Synthase
Antioxidants & Redox Signaling, 2003Nitric oxide synthase activity was recognized in rat renal cortex mitochondria (mtNOS) with nitric oxide (NO) production rates of 0.14-0.78 nmol/min/mg of protein. Rat pretreatment with enalapril (30 mg/kg/day i.p., up to 15 days) increased NO production in kidney, liver, and heart mitochondria.
Alberto, Boveris +5 more
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Inducible Nitric Oxide Synthase Expression
Current Protocols in Toxicology, 2000AbstractThis unit contains three protocols that can be used to determine iNOS expression in mouse macrophage‐like cells, RAW 264.7, by measuring end product, protein, and mRNA. A bacterial product, lipopolysaccharide (LPS), stimulates iNOS expression in RAW 264.7 cells.
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Nitric oxide synthase in invertebrates
The Histochemical Journal, 1995The gas nitric oxide is now recognized as an important signalling molecule that is synthesized from L-arginine by the enzyme nitric oxide synthase. This enzyme can be localized by different methods, including immunocytochemistry and the histochemical reaction for NADPH diaphorase.
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Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers
2020Generation of nitric oxide (NO) by the nitric oxide synthase (NOS) enzymes plays multiple signalling roles in every organ system, with crucial roles in the cardiovascular system, mediated by endothelial nitric oxide synthase (eNOS, encoded by NOS3) and neuronal nitric oxide synthase (nNOS, encoded by NOS1) in regulation of blood pressure, flow, oxygen ...
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NITRIC OXIDE SYNTHASES: WHY SO COMPLEX?
Annual Review of Nutrition, 1994INTRODUCIlON . • . • • • • • • • . • • • • • • . . • • • • • • • • • • • . . • • • • • . • . • • . . . . . • • . . . . • . • 131 BIOLOGY OF NITRIC OXIDE AND NITRIC OXIDE SYNTHASES . • . . . . . . . • . . . . 132 CHARACTERIZATION OF NITRIC OXIDE SYNTHASES . . • . . . . . . . . . . . . . . • . . . 134 Biochemistry 134 Mechanism • • . . . . • • . • . • .
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Electronic defects in metal oxide photocatalysts
Nature Reviews Materials, 2022Ernest Pastor +2 more
exaly
The kinetics of metal oxide photoanodes from charge generation to catalysis
Nature Reviews Materials, 2021Sacha Corby, R R Rao, Ludmilla Steier
exaly