Results 281 to 290 of about 361,848 (377)

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

open access: yesVIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

Neuronal Nitric Oxide Synthase

open access: yes, 2017
Seyed AkbarMoosavi   +2 more
openaire   +3 more sources

P2Y2 Inhibition Modifies the Anabolic Response to Exercise in Adult Mice

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Inhibition of the P2Y2 receptor with AR‐C118925XX (ARC) inhibits osteocytes induction of osteoclast differentiation. Treating adult mice with ARC prevents age‐related bone loss and increase endocortical bone formation. At the same time, ARC also enhances the anabolic response to exercise in aged mice by increasing the degree of periosteal bone ...
Amit Chougule   +6 more
wiley   +1 more source

CAV1 Exacerbates Renal Tubular Epithelial Cell Senescence by Suppressing CaMKK2/AMPK‐Mediated Autophagy

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
This study revealed that the expression of CAV1 is increased in the renal tissues of D‐gal‐induced aging mice and human renal proximal tubular epithelial cells (HK‐2). Using a GST pull‐down assay, it was demonstrated that CAV1 can directly bind to CaMKK2 and inhibit its activity, thereby suppressing the AMPK‐mediated autophagy process and exacerbating ...
Liya Sun   +9 more
wiley   +1 more source

Aging‐Associated Liver Sinusoidal Endothelial Cells Dysfunction Aggravates the Progression of Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Aged rats and human are more susceptible to MASLD‐related liver injury, steatosis, and fibrosis, accompanied by worsening of endothelial dysfunction. The SIRT1/p‐eNOS/NO pathway is involved in aggravated MASLD caused by aging‐related LSECs dysfunction.
Qingqing Dai   +5 more
wiley   +1 more source

Cerebrospinal Fluid Nitric Oxide Synthase is a Potential Mediator Between Cigarette Smoke Exposure and Sleep Disorders. [PDF]

open access: yesNat Sci Sleep
Lao J   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy