Results 271 to 280 of about 347,268 (305)

Nitric Oxide Synthase Inhibitors

2003
In 1990, several studies reported that an enhanced formation of endogenous nitric oxide (NO) contributes to the hypotension caused by endotoxin and tumor-necrosis factor-α (TNFα) (1-3). In addition, it became apparent that this overproduction of NO also plays an important role in the pathophysiology of the vascular hyporesponsiveness to vasoconstrictor
D K, Siriwardena, H, Tagori, C, Thiemermann   +2 more
openaire   +2 more sources

Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase

2017
Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon microbial and cytokine stimulation. It is needed for host defense against pathogens and for immune regulation.
Martin, Lee, Kevin, Rey, Katrina, Besler, Christine, Wang, Jonathan, Choy   +4 more
openaire   +2 more sources

Nitric Oxide Synthase

2006
The discovery of the L–arginine:NO pathway has proven to be one of the most important and exciting scientific developments of the last decade. This pathway is involved in a myriad of physiologic roles that range from the control of vascular tone and blood pressure to the modulation of skeletal muscle function.
Nicolas J. Guzman, Bismark Amoah-Apraku
  +4 more sources

Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers

2020
Generation of nitric oxide (NO) by the nitric oxide synthase (NOS) enzymes plays multiple signalling roles in every organ system, with crucial roles in the cardiovascular system, mediated by endothelial nitric oxide synthase (eNOS, encoded by NOS3) and neuronal nitric oxide synthase (nNOS, encoded by NOS1) in regulation of blood pressure, flow, oxygen ...
openaire   +2 more sources

Nitric Oxide Synthase

2003
A, Aljada, P, Dandona
openaire   +2 more sources

Nitric oxide/nitric oxide synthase in the pathogenesis of pulmonary emphysema

Respiratory Investigation, 2022
Kazuhiro, Yatera, Hiroshi, Mukae
openaire   +2 more sources

Inducible nitric oxide synthase: Regulation, structure, and inhibition

Medicinal Research Reviews, 2020
Maris A Cinelli, Galen P Miley, Richard B Silverman   +2 more
exaly  

Enzymology of Nitric Oxide Synthases

2003
B, Hemmens, B, Mayer
openaire   +2 more sources

Neuronal Nitric Oxide Synthase Protects Against Myocardial Infarction-Induced Ventricular Arrhythmia and Mortality in Mice

Circulation, 2009
Dylan Bürger, Xiangru Lu, Ming Lei
exaly  

Cardiac Myocyte–Specific Expression of Inducible Nitric Oxide Synthase Protects Against Ischemia/Reperfusion Injury by Preventing Mitochondrial Permeability Transition

Circulation, 2008
Gregg Rokosh, Murugesan Velayutham, Yu-Ting Xuan   +2 more
exaly