Results 21 to 30 of about 361,848 (377)

Tetrahydrobiopterin in nitric oxide synthase [PDF]

IUBMB Life, 2013
AbstractSummary: Nitric oxide synthase (NOS) is a critical enzyme for the production of the messenger molecule nitric oxide (NO) from L‐arginine. NOS enzymes require tetrahydrobiopterin as a cofactor for NO synthesis. Besides being one of the few enzymes to use this cofactor, the role of tetrahydrobiopterin in NOS catalytic mechanism is different from ...
Dennis J. Stuehr, Jesús Tejero
openaire   +2 more sources

ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY

Фармация и фармакология (Пятигорск), 2022
Nitric oxide as a therapeutic approach to the treatment of cardiovascular diseases attracted the attention of researchers at the end of the 19th century.
D. V. Kurkin, E. E. Abrosimova, D. A. Bakulin, N. S. Kovalev, M. A. Dubrovina, A. V. Borisov, A. V. Strygin, E. I. Morkovin, I. N. Tyurenkov   +8 more
doaj   +1 more source

Importance of endothelial nitric oxide synthase for the hypothermic protection of lungs against ischemia-reperfusion injury [PDF]

, 2006
ObjectivesThe hypothesis that the protective effects of mild hypothermia against the pulmonary ischemia-reperfusion injury are mediated by endothelial nitric oxide synthase was tested.MethodsEndothelial nitric oxide synthase knock-out and wild-type mice ...
Kaminski, Alexander, Kasch, Cornelius, Kumar, Sanjeev, Ladilov, Yury, Sponholz, Christoph, Stamm, Christof, Steinhoff, Gustav, Zhang, Li   +7 more
core   +1 more source

Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy

Cardiovascular Ultrasound, 2006
Background Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with ...
Arslan Erol, Barcin Cem, Sezer Murat, Ozbek Ugur, Ekmekci C Gokhan, Olcay Ayhan, Boztosun Bilal, Nisanci Yilmaz   +7 more
doaj   +1 more source

Emergent dynamics in an astrocyte-neuronal network coupled via nitric oxide [PDF]

, 2022
In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The "glissandi" effect is one such phenomenon, associated with a decrease in infraslow fluctuations, in which synchronized ...
arxiv   +1 more source

Inhibition of Nitric Oxide Synthase Impairs a Distinct Form of Long-Term Memory in the Honeybee, Apis mellifera [PDF]

, 1996
Nitric oxide has been shown to be implicated in neural plasticity that underlies processes of learning and memory. In the honeybee, studies on the role of nitric oxide in associative olfactory learning reveal its specific function in memory formation ...
Müller, Uli
core   +1 more source

Nitric oxide and nitric oxide synthase in Huntington's disease [PDF]

Journal of Neuroscience Research, 2001
AbstractNitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function ...
openaire   +3 more sources

Effects of Chitosan on the Secretion of Cytokines and Expression of Inducible Nitric Oxide Synthase mRNA in Peritoneal Macrophages of Broiler Chicken

Brazilian Archives of Biology and Technology, 2014
An in vitro experiment was conducted to study the effects of chitosan on the secretion of cytokines and expression of inducible nitric oxide synthase mRNA in peritoneal macrophages of broiler chicken.
Huiying Li, Binlin Shi, Sumei Yan, Tianzhang Zhao, Junliang Li, Xiaoyu Guo   +5 more
doaj   +1 more source

Low NO bioavailability in CCl(4 )cirrhotic rat livers might result from low NO synthesis combined with decreased superoxide dismutase activity allowing superoxide-mediated NO breakdown: A comparison of two portal hypertensive rat models with healthy controls [PDF]

, 2003
BACKGROUND: In cirrhotic livers, the balance of vasoactive substances is in favour of vasoconstrictors with relatively insufficient nitric oxide.
Fevery, Johan, Nevens, Frederik, Reichen, Jürg, Van de Casteele, Marc, van Pelt, Jos F   +4 more
core   +2 more sources

NOS1AP is a novel molecular target and critical factor in TDP-43 pathology [PDF]

, 2022
Cappelli et al. reported that Nitric Oxide Synthase 1 Adaptor Protein is a co-regulated transcript of the TAR DNA-binding protein 43 kDa, reduced in amyotrophic lateral sclerosis and frontotemporal lobar degeneration patients with TAR DNA-binding protein
Alida Spalloni, Andrea Malaspina, Anna-Leigh Brown, Avindra Nath, Bin Zhang, Brent Harris, Colin Smith, Corey McMillan, Dale J Lange, Daniel J MacGowan, Darius J Adams, Dhruv Sareen, Edward B Lee, Efthimios Dardiotis, Eleonora Aronica, Emanuele Buratti, Eran Hornstein, Ernest Fraenkel, Fabian Feiguin, Frank Baas, Giovanna Borsellino, Giulia Visani, Gregory A Cox, Hemali Phatnani, Hemali Phatnani, Iris Broce, James D Berry, James R Broach, Jennifer Phillips-Cremins, John Crary, John Ravits, Joshua Dubnau, Justin Kwan, Leonidas Stefanis, Leslie M Thompson, Lyle W Ostrow, Marc Gotkine, Marco De Bardi, Maria Secrier, Mary Poss, Matt Harms, Maurizio Romano, Molly G Hammell, Nazem Atassi, Neil A Shneider, Nikolaos. A Patsopoulos, Noah Zaitlen, null null, Oleg Butovsky, Ophir Shalem, Patrizia Longone, Pietro Fratta, Pietro Fratta, Robert Bowser, Robert H Baloh, Sabrina Paganoni, Sara Cappelli, Siddharthan Chandran, Steve Finkbeiner, Suma Babu, Suvankar Pal, Terry Heiman-Patterson, Timothy M Miller, Towfique Raj, Urša Šušnjar, Vilas Menon, Vivian Drory, Vivianna M Van Deerlin, Ximena Arcila-Londono, Zachary Simmons   +69 more
core   +2 more sources