Results 21 to 30 of about 462,598 (258)

ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY

open access: yesФармация и фармакология (Пятигорск), 2022
Nitric oxide as a therapeutic approach to the treatment of cardiovascular diseases attracted the attention of researchers at the end of the 19th century.
D. V. Kurkin   +8 more
doaj   +1 more source

Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: effect of ecNOS polymorphism on left ventricular hypertrophy

open access: yesCardiovascular Ultrasound, 2006
Background Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with ...
Arslan Erol   +7 more
doaj   +1 more source

Adenosine preconditioning attenuates hepatic reperfusion injury in the rat by preventing the down-regulation of endothelial nitric oxide synthase

open access: yesBMC Gastroenterology, 2002
Background Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet been investigated. Methods Wistar
Williamson Robin CN   +4 more
doaj   +1 more source

The Expression of Type-1 and Type-2 Nitric Oxide Synthase in Selected Tissues of the Gastrointestinal Tract during Mixed Mycotoxicosis

open access: yesToxins, 2013
The aim of the study was to verify the hypothesis that intoxication with low doses of mycotoxins leads to changes in the mRNA expression levels of nitric oxide synthase-1 and nitric oxide synthase-2 genes in tissues of the gastrointestinal tract and the ...
Magdalena Gajęcka   +4 more
doaj   +1 more source

Nitric oxide and nitric oxide synthase in Huntington's disease [PDF]

open access: yesJournal of Neuroscience Research, 2001
AbstractNitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function ...
openaire   +3 more sources

Nitric oxide synthases in mammals [PDF]

open access: yesBiochemical Journal, 1994
Nitric oxide is an inorganic free radical gas, of formula *N=O (abbreviated as NO). The discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L-arginine as a transcellular signal [1-4] was initially received by most biologists with considerable scepticism.
Salvador Moncada, Richard G. Knowles
openaire   +2 more sources

Effects of Chitosan on the Secretion of Cytokines and Expression of Inducible Nitric Oxide Synthase mRNA in Peritoneal Macrophages of Broiler Chicken

open access: yesBrazilian Archives of Biology and Technology, 2014
An in vitro experiment was conducted to study the effects of chitosan on the secretion of cytokines and expression of inducible nitric oxide synthase mRNA in peritoneal macrophages of broiler chicken.
Huiying Li   +5 more
doaj   +1 more source

Study of the nitric oxide system in the rat cerebellum during aging

open access: yesBMC Neuroscience, 2010
Background The cerebellum is the neural structure with the highest levels of nitric oxide, a neurotransmitter that has been proposed to play a key role in the brain aging, although knowledge concerning its contribution to cerebellar senescence is still ...
Martinez-Lara Esther   +9 more
doaj   +1 more source

Nitric Oxide Synthase Inhibitors as Antidepressants [PDF]

open access: yesPharmaceuticals, 2010
Affective and anxiety disorders are widely distributed disorders with severe social and economic effects. Evidence is emphatic that effective treatment helps to restore function and quality of life. Due to the action of most modern antidepressant drugs, serotonergic mechanisms have traditionally been suggested to play major roles in the pathophysiology
Wegener, Gregers, Volke, Vallo
openaire   +5 more sources

BACTERIAL NITRIC OXIDE SYNTHASE

open access: yesMìkrobìologìâ ì Bìotehnologìâ, 2011
The article provides the overview of modern scientific publications on the molecular structure, the mechanisms of synthesis of NO, molecular biology, genetics and biological function of bacterial nitric oxide synthase.
Б. М. Галкін   +2 more
doaj   +1 more source

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