Results 21 to 30 of about 462,598 (258)
Nitric oxide as a therapeutic approach to the treatment of cardiovascular diseases attracted the attention of researchers at the end of the 19th century.
D. V. Kurkin+8 more
doaj +1 more source
Background Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with ...
Arslan Erol+7 more
doaj +1 more source
Background Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet been investigated. Methods Wistar
Williamson Robin CN+4 more
doaj +1 more source
The aim of the study was to verify the hypothesis that intoxication with low doses of mycotoxins leads to changes in the mRNA expression levels of nitric oxide synthase-1 and nitric oxide synthase-2 genes in tissues of the gastrointestinal tract and the ...
Magdalena Gajęcka+4 more
doaj +1 more source
Nitric oxide and nitric oxide synthase in Huntington's disease [PDF]
AbstractNitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function ...
openaire +3 more sources
Nitric oxide synthases in mammals [PDF]
Nitric oxide is an inorganic free radical gas, of formula *N=O (abbreviated as NO). The discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L-arginine as a transcellular signal [1-4] was initially received by most biologists with considerable scepticism.
Salvador Moncada, Richard G. Knowles
openaire +2 more sources
An in vitro experiment was conducted to study the effects of chitosan on the secretion of cytokines and expression of inducible nitric oxide synthase mRNA in peritoneal macrophages of broiler chicken.
Huiying Li+5 more
doaj +1 more source
Study of the nitric oxide system in the rat cerebellum during aging
Background The cerebellum is the neural structure with the highest levels of nitric oxide, a neurotransmitter that has been proposed to play a key role in the brain aging, although knowledge concerning its contribution to cerebellar senescence is still ...
Martinez-Lara Esther+9 more
doaj +1 more source
Nitric Oxide Synthase Inhibitors as Antidepressants [PDF]
Affective and anxiety disorders are widely distributed disorders with severe social and economic effects. Evidence is emphatic that effective treatment helps to restore function and quality of life. Due to the action of most modern antidepressant drugs, serotonergic mechanisms have traditionally been suggested to play major roles in the pathophysiology
Wegener, Gregers, Volke, Vallo
openaire +5 more sources
BACTERIAL NITRIC OXIDE SYNTHASE
The article provides the overview of modern scientific publications on the molecular structure, the mechanisms of synthesis of NO, molecular biology, genetics and biological function of bacterial nitric oxide synthase.
Б. М. Галкін+2 more
doaj +1 more source