Results 61 to 70 of about 646,019 (403)

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source

Further observations on the role of nitric oxide in the feline lateral geniculate nucleus [PDF]

, 1996
[Abstract] We have examined the responses of a population of 77 cells in the dorsal lateral geniculate nucleus (dLGN) of the anaesthetized, paralysed cat.
Bickford, Black, Bohme, Bredt, Bult, Cleland, Cudeiro, Cudeiro, Dawson, Dawson, Derrington, Desai, Do, Eccles, Enroth-Cugell, Eysel, Funke, Garthwaite, Garthwaite, Garthwaite, Haley, Hartveit, Heggelund, Ito, Izumi, Kemp, Kwon, Lei, Lipton, Lipton, Lo, Lonart, Lorrain, Lundberg, Manzoni, Mayer, McCormick, McCormick, McCormick, Moncada, Montague, Murphy, Nowak, O'Dell, Pape, Pape, Scharfman, Schuman, Schuman, Shibuki, Sillito, Sillito, Sillito, Sillito, Sillito, Sillito, Singer, Snyder, Steriade, Vidyasagar, Wood   +60 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The protective effects of tadalafil on renal damage following ischemia reperfusion injury in rats

Kaohsiung Journal of Medical Sciences, 2015
Ischemia-reperfusion injury can cause renal damage, and phosphodiesterase inhibitors are reported to regulate antioxidant activity. We investigated the prevention of renal damage using tadalafil after renal ischemia reperfusion (I/R) injury in rats.
Bulent Erol, Tugrul Turker, Adem Tok, Sibel Bektas, Gorkem Mungan, Seyma Ozkanli, Bugra Karakas, Husnu Tokgoz, Bulent Akduman, Aydin Mungan   +9 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Nitric Oxide and Hydrogen Peroxide Production are Involved in Systemic Drought Tolerance Induced by 2R,3R-Butanediol in Arabidopsis thaliana

The Plant Pathology Journal, 2013
2R,3R-Butanediol, a volatile compound produced by certain rhizobacteria, is involved in induced drought tolerance in Arabidopsis thaliana through mechanisms involving stomatal closure.
Song-Mi Cho, Yong Hwan Kim, Anne J. Anderson, Young Cheol Kim   +3 more
doaj   +1 more source

Trigeminocardiac reflex by mandibular extension on rat pial microcirculation: role of nitric oxide. [PDF]

PLoS ONE, 2014
In the present study we have extended our previous findings about the effects of 10 minutes of passive mandibular extension in anesthetized Wistar rats. By prolonging the observation time to 3 hours, we showed that 10 minutes mandibular extension caused ...
Dominga Lapi, Giuseppe Federighi, M Paola Fantozzi, Cristina Del Seppia, Sergio Ghione, Antonio Colantuoni, Rossana Scuri   +6 more
doaj   +1 more source

Evaluation of serum nitric oxide synthase levels in patients with coronary slow flow based on corrected TIMI frame count

Archives of Medical Science: Atherosclerotic Diseases, 2023
Introduction The coronary slow flow phenomenon (CSFP) finding in angiography is characterized by the delayed filling of the terminal vessels without significant epicardial coronary disease.
Jamal Shamsara, Sepideh Elyasi, Mostafa Dastani, Nadia Behzadian, Hesamoddin Hosseinjani, Mahshid Ataei, Fatemeh Jafari, Mahdi Akbarzadeh, Mahshid Naserifar, Amirhossein Sahebkar, Amir Hooshang Mohammadpour   +10 more
doaj   +1 more source

Effects of NO synthase inhibitors on the synovial microcirculation in the mouse knee joint [PDF]

, 1999
Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses.
Krombach, F., Messmer, K., Refior, H. J., Veihelmann, A.   +3 more
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source