Results 101 to 110 of about 437,208 (310)
Molecules, 2016 Renin-angiotensin system (RAS) activation promotes oxidative stress which increases the risk of cardiac dysfunction in metabolic syndrome (MetS) and favors local insulin resistance. Fibrates regulate RAS improving MetS, type-2 diabetes and cardiovascular
Luz Ibarra-Lara +9 more
doaj +1 more source
Advanced Science, EarlyView.The deficient TiO2 (DTO) and Barium titanate (BTO) heterojunction treats osteomyelitis through SDT. The spin‐polarization effect induced by the unpaired spin electrons in Ti atoms can expedite the transfer of ultrasonic piezoelectric charges in BTO, enhancing surface sonocatalytic efficiency.
Chaofeng Wang +10 more
wiley +1 more source
Post-Outburst Chemistry in a Very Low-Luminosity Object: Peculiar High Abundance of Nitric Oxide [PDF]
A&A 691, A281 (2024)Abridged: Very Low Luminosity Objects (VeLLOs) are deeply embedded, and extremely faint objects and are thought to be in the quiescent phase of the episodic accretion process. They fill an important gap in our understanding of star formation. The VeLLO in the isolated DC3272+18 cloud has undergone an outburst, and is thus an ideal target for ...
arxiv +1 more source
Advanced Science, EarlyView.Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen +9 more
wiley +1 more source
Redox Biology, 2021 Non-thermal plasma (NTP), an engineered technology to generate reactive species, induces ferroptosis and/or apoptosis specifically in various-type cancer cells.
Li Jiang +12 more
doaj
Nitric Oxide as stress inducer and synchronizer of p53 dynamics [PDF]
arXiv, 2014 We study how the temporal behaviours of p53 and MDM2 are affected by stress inducing bioactive molecules NO (Nitric Oxide) in the p53-MDM2-NO regulatory network. We also study synchronization among a group of identical stress systems arranged in a three dimensional array with nearest neighbour diffusive coupling.
arxiv
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
Advanced Science, EarlyView.During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong +9 more
wiley +1 more source
Advanced Science, EarlyView.The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou +14 more
wiley +1 more source
Advanced Science, EarlyView.Carbon nanosol (CNS) exhibits rapid root penetration capacity, enhancing plant growth through boosting stomatal density and antioxidative enzyme activity. Single‐cell transcriptomic profiling uncovers cell type‐specific gene expression patterns and developmental trajectories during CNS‐mediated growth promotion.
Lingtong Cheng +10 more
wiley +1 more source
Characterisation of type I and type II nNOS-expressing interneurons in the barrel cortex of mouse
Frontiers in Neural Circuits, 2012 In the neocortex, neuronal Nitric Oxide-Synthase (nNOS) is essentially expressed in two sets of GABAergic neurons: type I neurons displaying a high expression and type II neurons displaying a weaker expression.
Quentin ePerrenoud +8 more
doaj +1 more source