The Effects of Quercetin on Vascular Endothelium, Inflammation, Cardiovascular Disease and Lipid Metabolism-A Review. [PDF]
NutrientsOzorowski M +6 more
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Effects of <i>Cnidium officinale</i>, <i>Pueraria lobata</i> Ohwi, and <i>Leonurus japonicus</i> Extract on Vascular Endothelial Dysfunctions in Ovariectomized Rats and Molecular Mechanisms. [PDF]
Int J Mol SciOh J +5 more
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Effects of Different Doses of Glucosamine Hydrochloride on Cartilage Tissue and Levels of Joint Injury Markers in Knee Osteoarthritis. [PDF]
J Cell Mol MedWang X, Hu B, Cheng Y, Chen W, Liu M.
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Clinicopathological study of fractional exhaled nitric oxide dynamics and intratumoral inducible nitric oxide synthase expression in primary lung cancer patients. [PDF]
Transl Cancer ResOkamoto K +4 more
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Nitric oxide synthase type‐II is synthesized by human gingival tissue and cultured human gingival fibroblasts [PDF]
Journal of Periodontal Research, 2000 Nitric oxide is known to be an important inflammatory mediator, and is implicated in the pathophysiology of a range of inflammatory disorders. The aim of this study was to determine the localization and distribution of endothelial NOS (NOSII) in human gingival tissue, and to ascertain if human gingival fibroblasts express NOS‐II when stimulated with ...
H. K. Kendall +4 more
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Nitric Oxide Synthase Type II mRNA Stability Is Translation‐ and Transcription‐Dependent
Journal of Neurochemistry, 1996 Abstract: Nitric oxide synthase (NOS) type II is induced in many cell types in response to cytokines or endotoxin. The duration of type II NOS mRNA expression in astroglial cells and macrophages in vitro is brief, even in the continuous presence of inducers, and their removal dramatically accelerates mRNA decay.
Song Kyu Park, Seán Murphy
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Head & Neck, 2001 Nitric oxide (NO) has been implicated both in tumor progression and inhibition. This study investigated whether type II nitric oxide synthase (NOS2) expression correlated with cell proliferation in oral squamous cell carcinoma (OSCC) and dysplasia.Paraffin-embedded tissue samples of normal oral mucosa, OSCC, and dysplasia were assessed ...
Peter A. Brennan +4 more
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Endocrinology, 1995 Erectile dysfunction occurs frequently in human diabetes, and it is sometimes associated with hypogonadism. These conditions also develop in a model of insulin-dependent (type I) diabetes, the BB/WORdp (diabetic prone) rat but have not yet been investigated in the model of insulin-resistant (type II) diabetes, the BBZ/WOR rat.
Dolores Vernet
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Copper induces type II nitric oxide synthase in vivo
Free Radical Biology and Medicine, 2003Intravenous administration of copper (up to a final concentration of ca. 35 micromol/l in the plasma) led to a progressive, dramatic fall of mean arterial pressure in rats. Copper-induced pressure changes were comparable to those elicited by 2 mg/kg LPS, and were greatly prevented by previous infusion of the inducible NOS (NOS-II) inhibitors ...
CUZZOCREA S +4 more
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Type II nitric oxide synthase activity is cardio-protective in experimental sepsis
European Journal of Pharmacology, 2003Overproduction of nitric oxide (NO) via the induction of NO synthase (NOS) II is implicated in the pathogenesis of the refractory hypotension that characterizes septic shock. However, clinical trials of nonselective NOS inhibitors have failed to afford a mortality benefit in patients with sepsis, and in those with depressed left ventricular function ...
Timothy W. Evans +3 more
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