Results 41 to 50 of about 715,891 (290)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Arbuscular Mycorrhiza and Nitrification: Disentangling Processes and Players by Using Synthetic Nitrification Inhibitors

Applied and Environmental Microbiology, 2022
Nitrogen is one of the most important elements for all life on Earth. In soil, N is present in various chemical forms and is fiercely competed for by various microorganisms as well as plants.
Martin Dudáš, Petra Pjevac, Michala Kotianová, Kateřina Gančarčíková, Martin Rozmoš, Hana Hršelová, Petra Bukovská, Jan Jansa   +7 more
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Urease and nitrification inhibitors with drip fertigation strategies to mitigate global warming potential and improve water-nitrogen efficiency of maize under semi-arid regions

Agricultural Water Management
The limited availability of water resources and the significant loss of nitrogen oxides are severe constraints on agricultural development in dry-land agricultural systems of China.
Yang Sunling, Ali Shahzad, Meng Wang, Yueling Xi, Mohammed Rafi Shaik, Mujeeb Khan   +5 more
doaj   +1 more source

Effect of straw and inhibitors on the fate of nitrogen applied to paddy soil

Scientific Reports, 2020
A pot experiment was used to explore the distribution of fertilizer N and agronomic effects in a paddy soil-rice (Oryza sativa L.) system. Five treatments were set: without nitrogen, straw and inhibitor (C), urea (U), urea + straw (US), urea + urease ...
Chunxiao Yu, Xueshi Xie, Hengzhe Yang, Lijie Yang, Wentao Li, Kaikuo Wu, Weiming Zhang, Chen Feng, Dongpo Li, Zhijie Wu, Lili Zhang   +10 more
doaj   +1 more source

Fate of 15N-labelled ammonium nitrate with or without the new nitrification inhibitor DMPSA in an irrigated maize crop

, 2017
Nitrification inhibitors, originally proposed for nitrate leaching mitigation, are recommended as effective nitrous oxide (N2O) mitigation strategies.
Guardia, G., Cardenas, L. M., Guillermo Guardia, Elizabeth R. Dixon, Dixon, E. R., Antonio Vallejo, Sonia García-Marco, Vallejo, A., Garcia-Marco, S., Laura M. Cardenas, Dixon, Liz, Cardenas, Laura   +11 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Bacteriostatic action of nitrification inhibitors

Canadian Journal of Microbiology, 1982
Nitrification inhibitors were investigated in an attempt to establish whether such chemicals actually kill ammonium-oxidizing bacteria (bactericidal action) or whether bacteria remain viable but temporarily incapable of nitrification (bacteriostatic action).
Rodgers, G. A., Ashworth, J.
openaire   +1 more source

Corn Yield Response to the Use of a Nitrification Inhibitor with Anhydrous Ammonia [PDF]

, 2019
Nitrification inhibitors are used to delay the nitrification process, reducing nitrogen (N) loss. The increase of nitrogen fertilization efficiency could promote greater corn grain yields and reduce environmental losses.
D. A. Ruiz Diaz, Hansel, F. D., Ruiz Diaz, D. A., F. D. Hansel   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source