Angewandte Chemie, EarlyView.An electrochemical α‐C─H functionalization of nitramines enables the synthesis of molecules containing bifunctional energetic heterocycles with promising properties. A telescoped, HNO3‐free sequence involving nitration and azolation steps offers a safer, modular, and scalable platform for the synthesis of energetic compounds.
Wan‐Chen Cindy Lee +4 more
wiley +1 more source
Did organic compounds in the Tagish Lake meteorite form via catalytic processes in the solar nebula and within parent bodies? [PDF]
, 2003 Gilmour, I. +3 more
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Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives [PDF]
Bohdan A. Chalyk +3 more
openalex +1 more source
Angewandte Chemie, EarlyView.Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian +4 more
wiley +1 more source
A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications. [PDF]
J Comput ChemLo R, Ganguly B.
europepmc +1 more source
Molecular Design and Redox Chemistries for Aqueous Organic Redox Flow Batteries (AORFBs)
Angewandte Chemie, EarlyView.Aqueous organic redox flow batteries (AORFBs) are a promising frontier for sustainable long‐duration energy storage. This review highlights recent advances in redox‐active molecule design, structure‐property relationships, and degradation mechanisms, alongside pairing strategies and full‐cell engineering.
Pan Wang
wiley +1 more source
Regioselective Synthesis of 5-Substituted 3-(β-d-Glycopyranosyl)isoxazoles and -isoxazolines by 1,3-Dipolar Cycloaddition as Potential Anticancer Agents and Glycogen Phosphorylase Inhibitors. [PDF]
Int J Mol SciKaszás T +18 more
europepmc +1 more source
Interactional Features of (RO)4Ti Species and Their Zr and Hf Analogues
Angewandte Chemie, EarlyView.Computational and experimental studies reveal that Group 4 tetroxides form a new type of σ‐hole interaction with N and O nucleophiles, which we propose to name “titan bonds” (TnBs). These insights into Ti, Zr, and Hf interactions may aid in the rational design of more selective catalysts for aldol and oxidation reactions. Abstract Tetroxides of Group 4
Elisabetta Venturin +7 more
wiley +1 more source
Unveiling Hydrogen Bonding and Solvent Effects on Directed Nitrile Oxide [3 + 2] Cycloaddition Reactions: Selectivity of 2,2-Dimethylpropane Nitrile Oxide with Cyclopentenylbenzamide: An MEDT Study. [PDF]
ACS OmegaBenmetir S +6 more
europepmc +1 more source
Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs
Angewandte Chemie, EarlyView.A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee +4 more
wiley +1 more source