Results 51 to 60 of about 232,319 (335)

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

Advanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu, Mengyao Zhang, Zitong Qiu, Xinyi Liu, Yunsheng Dou, Sona Krizkova, Zheyi Li, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Homogenous catalysis of peroxynitrite conversion to nitrate by diaryl selenide: a theoretical investigation of the reaction mechanism

Frontiers in Chemistry
Quenching peroxynitrite (a reactive oxidant species) is a vital process in biological systems and environmental chemistry as it maintains redox balance and mitigates damaging effects in living cells and the environment.
Yuan Xue, Yuan Xue, Carrie Salmon, Valentin Gogonea, Valentin Gogonea, Valentin Gogonea   +5 more
doaj   +1 more source

Evolution des caractéristiques physico-chimiques de deux zones de frayères à sédimentation contrastée et premiers résultats de survie embryo-larvaire de truite commune (Salmo trutta)

Knowledge and Management of Aquatic Ecosystems, 1998
L'impact chimique et physique de la sédimentation sur la survie d'oeufs de Salmonidés a été étudié dans la partie amont de deux ruisseaux d'un même bassin à production salmonicole contrastée : le Moulinet qui présente une faible population de truites et ...
MASSA F., GRIMALDI C., BAGLINIERE J. L., PRUNET P.   +3 more
doaj   +1 more source

Isoform-Specific NO Synthesis by Arabidopsis thaliana Nitrate Reductase

Plants, 2019
Nitrate reductase (NR) is important for higher land plants, as it catalyzes the rate-limiting step in the nitrate assimilation pathway, the two-electron reduction of nitrate to nitrite.
Marie Agatha Mohn, Besarta Thaqi, Katrin Fischer-Schrader   +2 more
doaj   +1 more source

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2018
Importance There are few effective treatments for heart failure with preserved ejection fraction (HFpEF). Short-term administration of inorganic nitrite or nitrate preparations has been shown to enhance nitric oxide signaling, which may improve aerobic ...
B. Borlaug, K. Anstrom, Gregory D. Lewis, Sanjiv J. Shah, J. Levine, Gabe A. Koepp, M. Givertz, G. Felker, M. M. Lewinter, Douglas L. Mann, Kenneth B. Margulies, Andrew L. Smith, W. W. Tang, D. Whellan, Horng H. Chen, V. Dávila-Román, S. McNulty, P. Desvigne‐Nickens, Adrian F. Hernandez, E. Braunwald, M. Redfield   +20 more
semanticscholar   +1 more source

Deployable 3D‐Printed Vascular Stent with Surface‐Catalysed Endogenous Nitric Oxide Generation

Advanced Materials, EarlyView.
A deployable 3D‐printed vascular stent was fabricated with surface‐catalyzed endogenous nitric oxide generation, representing a promising new direction for stent development. The stent can be remotely controlled by magnetic force in its compressed state and fully deployed at the target site using an untethered heat source, potentially eliminating the ...
Kun Zhou, Zifei Han, Kang Lin, Di Wu, Siti Nur Asyura Adzlan, Qingqing Fan, Christina Cortez‐Jugo, Rona Chandrawati, Cyrille Boyer   +8 more
wiley   +1 more source

Effect of Dry Red Grape Pomace as a Nitrite Substitute on the Microbiological and Physicochemical Properties and Residual Nitrite of Dry-cured Sausage

Nutrition and Food Sciences Research, 2016
Background and Objectives: Sodium nitrite and potassium nitrite have been traditionally used for inhibition of Clostridium botulinum and also as an agent to stabilize the color of meat products; however, usage of these additives at high levels could lead
Fatemeh Riazi, Fariba Zeynali, Ebrahim Hoseini, Homa Behmadi   +3 more
doaj  

Molecular underpinnings of nitrite effect on CymA-dependent respiration in Shewanella oneidensis

Frontiers in Microbiology, 2016
Shewanella exhibit a remarkable versatility of respiration, with a diverse array of electron acceptors (EAs). In environments where these bacteria thrive, multiple EAs are usually present.
Miao Jin, Huihui Fu, Jianhua Yin, Jie Yuan, Haichun Gao   +4 more
doaj   +1 more source

Inter‐Atomic Synergy on Single‐Atom Alloy Promotes Cyclohexanone Oxime Electrosynthesis

Advanced Materials, EarlyView.
Electrosynthesis of cyclohexanone oxime using renewable electricity offers a greener alternative to traditional energy‐intensive methods. Here, we develop a Fe1Bi single‐atom alloy that delivers 70.9% Faradaic efficiency and 0.94 mmol cm−2 h−1 yield rate through the atomic‐scale synergistic mechanism.
Panlong Zhai, Chen Wang, Guan Sheng, Chao Ye, Jungang Hou, Qinfen Gu, Tao Ling, Ye Zhu, Pei Liang, Xin Wang, Jieqiong Shan   +10 more
wiley   +1 more source