Detection of banned nitrofuran metabolites in animal plasma samples using UHPLC–MS/MS [PDF]
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2011 The use of nitrofurans as veterinary drugs in food-producing animals has been banned in the EU since the 1990s. Monitoring programs in the EU are based on the detection of protein-bound metabolites after slaughter. An UHPLC-MS/MS method was developed and validated for pre slaughter determination of four nitrofuran metabolites (AHD, AOZ, SEM, AMOZ) in ...
Anita Radovnikovic +2 more
exaly +5 more sources
Presence of antibacterial substances, nitrofuran metabolites and other chemicals in farmed pangasius and tilapia in Bangladesh: Probabilistic health risk assessment [PDF]
Toxicology Reports, 2021 Intensive feeding and the use of drugs and other chemicals for enhancing yield characterised commercial pangasius and tilapia aquaculture in Bangladesh.
Md. Mehedi Alam, Mohammad Mahfujul Haque
doaj +2 more sources
Development and validation of confirmatory method for analysis of nitrofuran metabolites in milk, honey, poultry meat and fish by liquid chromatography-mass spectrometry [PDF]
Macedonian Veterinary Review, 2016 In this study we have devoloped and validated a confirmatory analysis method for nitrofuran metabolites, which is in accordance with European Commission Decision 2002/657/EC requirements.
Fatih Alkan +2 more
doaj +3 more sources
Stability studies of the metabolites of nitrofuran antibiotics during storage and cooking
Food Additives and Contaminants, 2007 Nitrofuran antibiotics cannot be used in food production within the European Union because of their potential health risks to consumers. The recent discovery of their widespread use in global food industries and the finding of semicarbazide in baby food as a result of packaging contamination have focused attention on the toxicity and stability of these
Cooper, K. M., Kennedy, D. G.
openaire +5 more sources
Determination of nitrofuran metabolites in sausage casings and crawfish using LC-Q-Orbitrap HRMS: Method development and validation [PDF]
Toxicology ReportsThis study developed and validated an analytical method for determining four nitrofuran (NF) metabolites in sausage casings and crawfish matrices.
Omar Khaled +3 more
doaj +2 more sources
Development and Validation of a Confirmatory LC-MS/MS Method Using QuEChERS for Determination of Nitrofuran Metabolites in Eggs According to EU Regulation 2021/808 [PDF]
MoleculesNitrofurans are banned veterinary medicinal products due to their carcinogenic and mutagenic properties; however, their protein-bound metabolites (AOZ, AMOZ, AHD, SEM, and DNSAH) may persist in food-producing animals, particularly in eggs.
Elmira Marku +7 more
doaj +2 more sources
Determination of nitrofuran metabolites and nifurpirinol in animal tissues and eggs by ultra-high performance liquid chromatography-tandem mass spectrometry validated according to Regulation (EU) 2021/808 [PDF]
HeliyonIn this work, an analytical method for the determination of eight non-allowed nitrofurans, including nifurpirinol and the metabolites of furazolidone, furaltadone, nitrofurantoin, nitrofurazone, nifursol, nitrovin, and nifuroxazide in animal tissues ...
Francisco Moragues +3 more
doaj +2 more sources
Journal of Chemistry, 2022 In this study, a rough, cheap, easy-made wooden-tip-based solid-phase microextraction (SPME) probe was first developed for simultaneous determination of 4 nitrofuran metabolite derivatives in complex food matrices via LC-MS/MS.
Xiaoming Gong +6 more
doaj +2 more sources
Residues of nitrofuran antibiotic parent compounds and metabolites in eyes of broiler chickens
Food Additives & Contaminants: Part A, 2008 Nitrofuran antibiotic residues in food continue to be of international concern. The finding of sources of semicarbazide (SEM), other than through the misuse of nitrofurazone, present a challenge to the use of SEM as a definitive marker residue for this drug.
Cooper, K.M. +3 more
openaire +3 more sources
Journal of AOAC INTERNATIONAL, 2018 Abstract This paper describes a rapid and robust method utilizing a single liquid–liquid extraction for the quantitation and confirmation of chloramphenicol, florfenicol, and nitrofuran metabolites in honey. This methodology combines two previous extraction methods into a single extraction procedure and utilizes matrix-matched ...
Brian T, Veach +3 more
openaire +3 more sources