Results 41 to 50 of about 410,020 (135)

Novel 5-nitrofuran-activating reductase in Escherichia coli

, 2020
The global spread of multidrug resistant enterobacteria warrants new strategies to combat these pathogens. One possible approach is reconsideration of “old” antimicrobials which remain effective after decades of use.
Jasna Rakonjac (41315), Patrick Biggs (7022450), Christina Moon (14895354), David Wheeler (393528), Ieuan Davies (8251848), Vuong Le (8251839)   +5 more
core  

Nanotechnology as a Catalyst for Reintroducing Abandoned or Therapeutically Constrained Antimicrobial Agents: Opportunities and Translational Challenges

BioMed Research International, Volume 2026, Issue 1, 2026.
The global rise in antimicrobial resistance, increasing rates of emerging and re‐emerging viral infections, and the persistent burden of fungal and parasitic diseases have intensified the need for alternative anti‐infective therapeutic strategies; a challenge further compounded by the diminishing pipeline of novel therapeutic agents.
Babatunde Ibrahim Olowu, Olalekan Toheeb Okewale, Abdulhakeem Opeyemi Azeez, Shammah Oluwaseyi Adeyemi   +3 more
wiley   +1 more source

Quantitation and Confirmation of Chloramphenicol, Florfenicol, and Nitrofuran Metabolites in Honey Using LC-MS/MS

, 2018
This paper describes a rapid and robust method utilizing a single liquid–liquid extraction for the quantitation and confirmation of chloramphenicol, florfenicol, and nitrofuran metabolites in honey.
Brian T Veach, Renea Anglin, Thilak K Mudalige, Paula J Barnes   +3 more
core   +1 more source

Alternative and Synergistic Strategies Against Antibiotic‐Resistant Staphylococcus aureus in Clinical and Environmental Settings

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Antimicrobial resistance (AMR) in Staphylococcus aureus (S. aureus) poses a serious global health threat, undermining treatment outcomes and necessitating the development of innovative therapeutic strategies. Methicillin‐resistant Staphylococcus aureus (MRSA) is a major contributor to this burden, with increasing prevalence in hospitals, contaminated ...
Kiandokht Babolhavaeji, Sima Kazemi, Tahere Etesamifard, Rahmat Solgi, Abdelwahab Omri   +4 more
wiley   +1 more source

Nitrofuran antibiotic residues in pork The FoodBRAND retail survey

, 2004
Use of nitrofuran drugs in food-producing animals has been prohibited within the EU because they may represent a public health risk. Monitoring compliance with the ban has focused on the detection of protein-bound nitrofuran metabolites which, in ...
Conneely, A, van Rhijn, J A, Mulder, P P J, Rhijn, J.A., van, Conneely, A., Trigueros, G, Kovacsics, L, Kennedy, D.G., Kennedy, D G, Trigueros, G., O'Keeffe, M, Fodor, A., Fodor, A, Cooper, K M, O'Keeffe, M., Cooper, K.M., Kovacsics, L., Mulder, P.P.J.   +17 more
core   +1 more source

Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence

Interdisciplinary Perspectives on Infectious Diseases, Volume 2026, Issue 1, 2026.
Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organisms cause African trypanosomiasis, Chagas disease, and leishmaniasis, which are classified as neglected tropical diseases (NTDs).
Cynthia Mmalebna Amisigo, Aboagye Kwarteng Dofuor, Jennifer Afua Afrifa Yamoah, Albert Fynn Aiduenu, Blessing Kwabena Gayi, Angelina Akomea, Zenabu Lansah Alidu, Gideon Danso, Selina Mawunyo Ayivi-Tosuh, Naa Kwarley-Aba Quartey, Joseph Harold Nyarko Osei, Seyram Kofi Loh, William Ekloh, Suraiya Saleem   +13 more
wiley   +1 more source

Plant Uptake and Metabolism of Nitrofuran Antibiotics in Spring Onion Grown in Nitrofuran-Contaminated Soil

, 2017
Environmental pollution caused by the discharge of mutagenic and carcinogenic nitrofurans to the aquatic and soil environment is an emerging public health concern because of the potential in producing drug-resistant microbes and being uptaken by food ...
Yinan Wang, Wan Chan, K. K. Jason Chan, Wang, Yinan, Chan, K. K.Jason, Chan, Wan   +5 more
core   +1 more source

Cymbopogon densiflorus Essential Oil Increases Trypanosoma cruzi Membrane Permeability and Enhances the Benznidazole Activity When Combined on Micellar System: A Multitarget Strategy for Chagas Disease Chemotherapy

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
The limited efficacy and toxicity of benznidazole in the chronic stage of Chagas disease highlight the need for alternative and complementary therapeutic strategies. To expand current knowledge, the present study explores the mechanism of action of Cymbopogon densiflorus essential oil and its combination with benznidazole in micellar systems as a ...
Janaína Brandão Seibert, Tatiane Roquete Amparo, Tamires Cunha Almeida, Lucas Resende Dutra Sousa, Ivanildes Vasconcelos Rodrigues, Policarpo Ademar Sales Junior, Silvane Maria Fonseca Murta, Rodrigo Dian de Oliveira Aguiar Soares, Gustavo Henrique Bianco de Souza, Cláudia Martins Carneiro, Paula Melo de Abreu Vieira, Orlando David Henrique dos Santos, Munmun Bardhan   +12 more
wiley   +1 more source

Depletion of four nitrofuran antibiotics and their tissue-bound metabolites in porcine tissues and determination using LC-MS/MS and HPLC-UV

, 2005
Depletion of the nitrofuran antibiotics furazolidone, furaltadone, nitrofurantoin and nitrofurazone and their tissue-bound metabolites AOZ, AMOZ, AHD and SEM from pig muscle, liver and kidney tissues is described. Groups of pigs were given feed medicated
van Rhijn, J A, Mulder, P P J, Rhijn, J.A., van, Young, P B, Kovacsics, L, Kennedy, D.G., Kennedy, D G, McCracken, R.J., Cooper, K M, Young, P.B., Cooper, K.M., Kovacsics, L., McCracken, R J, Mulder, P.P.J.   +13 more
core   +1 more source

Phylogenetic Analysis and In Vitro Antimicrobial Potential of Some Herbal Extracts Against Multidrug‐Resistant Pseudomonas aeruginosa Isolate Recovered From Hospital Wastes

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
The emergence of multidrug‐resistant (MDR) Pseudomonas aeruginosa in healthcare settings poses a critical global health challenge, intensified by limited therapeutic options and the environmental spread of pathogens through hospital waste. This study addresses the urgent need for alternative strategies by investigating the phylogenetic profile and ...
Muhammad Nazir Uddin, Taha Fatima, Mian Syed Ali Shah, Ishaq Khan, Wajid Khan, Saeedah Musaed Almutairi, Mohamed Soliman Elshikh, Farman Ullah, Iftikhar Ali, Adnan Shahzad, Taj-ud-Din, Rajib Chowdhury   +11 more
wiley   +1 more source