Results 81 to 90 of about 726 (164)

A simplified modification to rapidly determine the residues of nitrofurans and their metabolites in aquatic animals by HPLC triple quadrupole mass spectrometry

open access: yes, 2021
A simplified method is described for reducing the analysis time of nitrofurans (NFs) and nitrofuran metabolites (NFMs) in the aquatic animals.
박세창   +8 more
core   +1 more source

Novel Prodrug Strategies for the Treatment of Tuberculosis

open access: yesChemistry – An Asian Journal, Volume 19, Issue 23, December 2, 2024.
This review summarises the prodrugs that are currently used in tuberculosis treatment regimens. In particular, nitroimidazole prodrugs that are bioactivated by the hypoxic intracellular environment of Mycobacterium tuberculosis are discussed in detail. Abstract The emergence of drug‐resistant strains of Mycobacterium tuberculosis (M.tb), the causative ...
Christine G. Kim   +3 more
wiley   +1 more source

Studies on metabolic activation of nitrofurans: Formation of active metabolites and their binding to cysteine and glutathione.

open access: yesJournal of Pharmacobio-Dynamics, 1978
When 14C-3-(5-nitro-2-furyl)-2-(2-furyl) acrylamide (AF-2) or 3H-methyl 3-(5-nitro-2-furyl)-2-phenylacrylate (MNFPA) was incubated with SH compounds such as cysteine and glutathione in purified milk xanthine oxidase-hypoxanthine system, the ethyl acetateextractable radioactivity from the reaction mixture was markedly decreased compared with the ...
TATSUMI, KIYOSHI   +4 more
openaire   +2 more sources

Effects of two common antibiotics on the skin microbiome of ornamental reef fishes: Implications for manipulative experiments in microbial dynamics

open access: yesAquaculture, Fish and Fisheries, Volume 4, Issue 3, June 2024.
We tested the effects of the antibiotics Enrofloxacin and Nitrofurazone in the skin microbiome of three reef fish species: the four‐eyed butterflyfish, Chaetodon capistratus, the neon goby Elacatinus oceanops, and the beaugregory damselfish Stegastes leucostictus using a 16S rRNA gene sequencing approach.
Ana Pereira   +6 more
wiley   +1 more source

Development and validation of a new method for determining nitrofuran metabolites in bovine urine using liquid chromatography - tandem mass spectrometry

open access: yes, 2013
Background. The use of nitrofurans as veterinary drugs in food-producing animals is banned throughout the European Union. Nevertheless, nitrofuran metabolites have been detected not only in animal products, but also in bovine urine.
Zawadzka, I., Rodziewicz, L.
core  

Determination of nitrofuran residues in milk by LC/MS/MS and assessment of human health risks in Ankara region, Turkey [PDF]

open access: yes
In this study, we investigated the occurrence of nitrofuran (NF) metabolites, namely 3-amino-2-oxazolidinone (AOZ), semicarbazide (SEM), 5-methylmorpholino-3-amino-2-oxazolidinone (AMOZ), and 1-aminohydantoin (AHD), in raw cow's milk and assessed the ...
Ince, S., Ozdemir, O.
core   +1 more source

Complete validation according to current international criteria of a confirmatory quantitative method for the determination of nitrofuran metabolites in seafood by liquid chromatography isotope dilution tandem mass spectrometry [PDF]

open access: yes, 2019
Despite the ban of nitrofurans (NFs) for use in food production in many countries in the 1990s, NF metabolites in food are still regularly detected during import control testing.
Rolfsnes, Britt Elin   +2 more
core   +1 more source

Simultaneous Determination of Nitrofuran Metabolites and Chloramphenicol in Shrimp with a Single Extraction and LC-MS/MS Analysis

open access: yesJournal of AOAC INTERNATIONAL, 2015
Abstract A method has been developed to quantify the nitrofuran metabolites 3-amino-5-morphorinomethyl-1,3-oxazolidinone, 3-amino-oxazolidinone, 1-aminohydantoin, and semicarbazide, as well as chloramphenicol in shrimp with a single extraction procedure followed by LC-MS/MS analysis. Dynamic selected reaction monitoring with positive and
Aref, El-Demerdash   +4 more
openaire   +2 more sources

Isolation of bound residues of nitrofuran drugs from tissue by solid-phase extraction with determination by liquid chromatography with UV and tandem mass spectrometric detection

open access: yes, 2003
Use of nitrofuran drugs in food-producing animals has been prohibited within the EU because they may represent a public health risk. Monitoring compliance with the ban has focused on the detection of protein-bound nitrofuran metabolites which, in ...
Fodor, A.   +9 more
core   +1 more source

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