The major difficulty in analysis of nitrofurans in feed, feed water, and food of animal origin is that nitrofurans have low molecular weights and fast metabolism.
Śniegocki Tomasz +3 more
doaj +2 more sources
Nitrofurans for External Use (Review) [PDF]
Introduction. Aspects of the use of nitrofurans for external use (nitrofural, furazolidone and furazidin) are described in the article. Review of current research that is dedicated to development of drugs containing nitrofuran derivatives has been ...
A. V. Beliatskaya +5 more
doaj +2 more sources
Development and Validation of a Confirmatory LC-MS/MS Method Using QuEChERS for Determination of Nitrofuran Metabolites in Eggs According to EU Regulation 2021/808 [PDF]
Nitrofurans are banned veterinary medicinal products due to their carcinogenic and mutagenic properties; however, their protein-bound metabolites (AOZ, AMOZ, AHD, SEM, and DNSAH) may persist in food-producing animals, particularly in eggs.
Elmira Marku +7 more
doaj +2 more sources
Acid‐Stable Nitrofuran Triple Therapy With Rabeprazole and Amoxicillin Targeting Helicobacter pylori Infection [PDF]
Overview: Novel nitrofuran derivatives were developed and evaluated against Helicobacter pylori to overcome antibiotic resistance and inflammation. Methods and Findings: In vitro assays using H. pylori 60190 and PMSS1 strains demonstrated potent antibacterial activity, reduced bacterial adhesion, and inhibited cytokine release from gastric epithelial ...
Nagendran Tharmalingam +7 more
wiley +2 more sources
Furagin Derivatives—Nitrofuran‐Based Hydrazones as Potential Dual Inhibitors of Thioredoxin Reductase and Carbonic Anhydrases [PDF]
Nitrofuran‐based hydrazones derived from furagin are developed as dual inhibitors of thioredoxin reductase 1 and cancer‐associated carbonic anhydrases IX and XII. The series shows selective enzyme inhibition with reduced off‐target carbonic anhydrase (CA) I/II activity, while lead compound 7g exhibits potent TrxR1 inhibition and moderate anticancer ...
Aleksandrs Pustenko +6 more
wiley +2 more sources
Electrochemical (Bio)Sensors for Antibiotic Residue Detection in Aquatic Animal Products: A Review [PDF]
The rapid and sensitive quantification of antibiotic residues in aquatic animals is crucial for ensuring food safety and protecting public health. Electrochemical (bio)sensors show great potential in this field due to their quick response time, low cost,
Meiqing Yang +4 more
doaj +2 more sources
Global Distribution and Comparative Resistance Profiles of Escherichia coli Isolated From Bovine Meat and Meat Products: Evidence From Network Meta‐Analysis [PDF]
Schematic overview of the study and its principal findings. E. coli isolated from bovine meat and meat products was evaluated for antimicrobial resistance using Bayesian network meta‐analysis. The graphical abstract highlights the antimicrobial resistance ranking based on SUCRA, showing high resistance to penicillin, doxycycline, amoxicillin ...
Yaser Khorram Del +5 more
wiley +2 more sources
Chromatographic detection of nitrofurans in foods of animal origin
Nitrofurans are antibacterials banned in livestock by different countries due to its relationship with the production of carcinogenic metabolites. Several studies have been conducted to find the best methodology to identify these residues.
César Aquiles Lázaro de la Torre +4 more
doaj +2 more sources
Molecular Periphery Design Allows Control of the New Nitrofurans Antimicrobial Selectivity [PDF]
A series of 13 new 3-substituted 5-(5-nitro-2-furyl)-1,2,4-oxadiazoles was synthesized from different aminonitriles. All compounds were screened in the disc diffusion test at a 100 μg/mL concentration to determine the bacterial growth inhibition zone ...
Lyubov Vinogradova +11 more
doaj +2 more sources
A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples [PDF]
In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention.
Xiaoling Zheng +5 more
doaj +2 more sources

