Results 21 to 30 of about 2,815 (210)

nitrofurans

, 2022
Archive of nitrofurans containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875), Silvia Gervasoni (6169202), Andrea Bosin (6743129), Helen I. Zgurskaya (3093648), Attilio Vittorio Vargiu (2358538), Paolo Ruggerone (247673)   +5 more
core   +1 more source

Studies on the Activation of Nitrofurans [PDF]

, 1980
Nitrofurans, initially developed in the 1940's as antibacterial agents, have recently been shown to have mutagenic and carcinogenic effects. Nitrofurans exert such effects after metabolism by bacterial and mammalian nitroreductases to produce short-lived,
Ramcharitar, Sharon Shyama
core   +2 more sources

Damage to Mammalian Cell DNA by Nitrofurans [PDF]

, 1976
Title: Damage to Mammalian Cell DNA by Nitrofurans, Author: Peggy L. Olive, Location: ThodeNitrofurans, initially developed in the 1940's as antibacterial agents, have recently been shown to be mutagens and carcinogens.
Olive, Peggy L.
core   +2 more sources

Evaluating 5-nitrofurans as trypanocidal agents. [PDF]

, 2020
The nitroheterocycle nifurtimox, as part of a nifurtimox-eflornithine combination therapy, represents one of a limited number of treatments targeting Trypanosoma brucei, the causative agent of human African trypanosomiasis.
Di Maio, R, Wilkinson, SR, Cerecetto, H, Bot, C, Alvarez, G, Hall, BS, González, M   +6 more
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Evaluation of the presence of nitrofurans in meat and chicken eggs [PDF]

, 2022
The nitrofurans are antimicrobial drugs that have been widely used as veterinary therapeutics or feed additives for treating bacterial diseases in cattle, swine and poultry production.
ENCIU, Valeriu, BURLACU, S., STICI, V.
core   +1 more source

ALDH2 mediates 5-nitrofuran activity in multiple species [PDF]

, 2012
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative ...
Spitzer, Michaela, Brear, Paul, Johnson, Stephen L, Patton, E Elizabeth, Zeng, Zhiqiang, Patton, Elizabeth, Mitchell, Amy, Ishizaki, Hironori, Taylor, Kerrie L, Smith, Terry K., Westwood, Nicholas J, Patton, E Elizabeth; id_orcid, Marie, K.L.; id_orcid, McNeil, Ewan, Temperley, Nicholas, Tyers, Mike, Melton, David W, Zhou, Linna, Temperley, Nicholas D, Gautier, Philippe, Taylor, Kerrie, Narayan, Vikram, Melton, David, Westwood, Nicholas James, Smith, Terry K, Johnson, Stephen, McNeil, Ewan M, Westwood, Nicholas James; id_orcid, Smith, Terry K; id_orcid, McNeil, Ewan M., Johnson, Stephen L., Temperley, Nicholas D., Patton, E. Elizabeth, Melton, David W., Westwood, Nicholas J.   +34 more
core   +1 more source

Correlated Transcriptional Responses Provide Insights into the Synergy Mechanisms of the Furazolidone, Vancomycin, and Sodium Deoxycholate Triple Combination in Escherichia coli

mSphere, 2021
Synergistic antibiotic combinations are a promising alternative strategy for developing effective therapies for multidrug-resistant bacterial infections.
Catrina Olivera, Murray P. Cox, Gareth J. Rowlands, Jasna Rakonjac   +3 more
doaj   +1 more source

Synthesis of Furan Derivatives Condensed with Carbohydrates

Molecules, 2001
Eight new furan derivatives have been prepared and characterized. These compounds were obtained by condensation of aminosugar and aminocyclitol intermediates with furan derivatives.
Wendel A. Alves, Marcelo S. Valle, Luciana D. Pinto, Leonardo J. A. Siqueira, Mireille Le Hyaric, Mauro V. de Almeida   +5 more
doaj   +1 more source

Antimicrobial Activity of N-ariliden(alkylidene)hydrazides of Carboxymethylalginic Acid

Разработка и регистрация лекарственных средств, 2019
Introduction. Nowadays, due to the emergence of new broad-spectrum antibiotics and synthetic chemotherapeutic agents, the use of nitrofuran has significantly decreased. At the same time, they remain important for the treatment of urinary tract infections
D. N. Kosareva, E. P. Ananieva, A. A. Iozep   +2 more
doaj   +1 more source

Treatment of canine cutaneous leishmaniasis by Leishmania (Viannia) braziliensis in dogs with furazolidone and β-cyclodextrin: case report.

Veterinaria Italiana, 2023
Euthanasia of animals is not accepted as a control for cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis and drugs used in humans for the treatment of leishmaniasis are not allowed for animals in Brazil.
Marcos Santos Zanini, Larissa Ataíde Siqueira, Yuri Vieira Almeida, Laisa Savergnini Poleze, Dante Gnecco Zanini , Roberto Ramos Sobreira, Ana Paula Madureira   +6 more
doaj   +1 more source