Results 21 to 30 of about 16,580 (169)

Aerobacterial Vaginosis among Women Attending an Infertility Clinic at a Tertiary Care Hospital in Chennai, India and Susceptibility Pattern of Isolates

Journal of Pure and Applied Microbiology, 2021
Genital infections and subsequent vaginosis diagnosed through high vaginal swab in women is caused due to fungi or bacteria. The presented study focused on determining the types, numbers and antibacterial susceptibility pattern of aerobic bacteria ...
Abigail R. Sopia, Pushpa Innocent D. Joseph, M. Kalyani, B. Ananthi, Suresh Dhanaraj, Allen John Henry   +5 more
doaj   +1 more source

Nitrofurantoin-induced immune-mediated lung and liver disease [PDF]

Vojnosanitetski Pregled, 2012
Introduction. Nitrofurantoin, a furan derivative, introduced in the fifties has widely been used as an effective agent for the treatment and prevention of urinary tract infections (UTI). Spectrum of adverse reactions to nitrofurantoin is wide, ranging
Milić Rade, Plavec Goran, Tufegdžić Ivana, Tomić Ilija, Šarac Sanja, Lončarević Olivera   +5 more
doaj   +1 more source

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, EarlyView.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

Community-acquired lower urinary tract infections: Etiology, antimicrobial resistance, and treatment results in female patients

Journal of Global Infectious Diseases, 2018
Background/Purpose: Most community-acquired urinary tract infections (UTIs) are usually treated empirically. The knowledge of antibiotic resistance patterns of the microorganisms causing UTI is essential for defining the empirical treatment.
Ilknur Erdem, Ridvan Kara Ali, Enes Ardic, Senay Elbasan Omar, Reyhan Mutlu, Aynur Eren Topkaya   +5 more
doaj   +1 more source

Nitrofurantoin Combined With Amikacin: A Promising Alternative Strategy for Combating MDR Uropathogenic Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2020
Urinary tract infections (UTI) are common infections that can be mild to life threatening. However, increased bacterial resistance and poor patient compliance rates have limited the effectiveness of conventional antibiotic therapies.
Zi-Xing Zhong, Zi-Xing Zhong, Ze-Hua Cui, Ze-Hua Cui, Xiao-Jie Li, Tian Tang, Tian Tang, Zi-Jian Zheng, Zi-Jian Zheng, Wei-Na Ni, Wei-Na Ni, Liang-Xing Fang, Liang-Xing Fang, Yu-Feng Zhou, Yu-Feng Zhou, Yang Yu, Yang Yu, Ya-Hong Liu, Ya-Hong Liu, Ya-Hong Liu, Xiao-Ping Liao, Xiao-Ping Liao, Xiao-Ping Liao, Jian Sun, Jian Sun, Jian Sun   +25 more
doaj   +1 more source

Development of Inhalable Spray Dried Nitrofurantoin Formulations for the Treatment of Emphysema

Pharmaceutics, 2022
A central characteristic of emphysematous progression is the continuous destruction of the lung extracellular matrix (ECM). Current treatments for emphysema have only addressed symptoms rather than preventing or reversing the loss of lung ECM ...
Mathew N. Leslie, Nirmal Marasini, Zara Sheikh, Paul M. Young, Daniela Traini, Hui Xin Ong   +5 more
doaj   +1 more source

Actionable Pharmacogenomics and Essential Medicines: An Analysis of WHO and African Lists for Safer and Efficacious Drug Use

Clinical Pharmacology &Therapeutics, EarlyView.
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Janine Scholefield, Collen Masimirembwa   +5 more
wiley   +1 more source

New Solid Forms of Nitrofurantoin and 4-Aminopyridine Salt: Influence of Salt Hydration Level on Crystal Packing and Physicochemical Properties

Molecules, 2022
The crystallization of the poorly soluble drug nitrofurantoin (NFT) with 4-aminopyridine (4AmPy) resulted in three multicomponent solid forms with different hydration levels: anhydrous salt [NFT+4AmPy] (1:1), salt monohydrate [NFT+4AmPy+H2O] (1:1:1), and
Denis E. Boycov, Ksenia V. Drozd, Alex N. Manin, Andrei V. Churakov, German L. Perlovich   +4 more
doaj   +1 more source

The Burden of Adverse Drug Reactions in Africa in the Context of Pharmacogenetics‐Based Clinical Guidelines

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation has a significant impact on patients' response to medicines. Variations in important pharmacogenes have been evaluated in several studies and consequently led to international guidelines from clinical pharmacogenomics consortia. However, there are limited examples of these being implemented across the African continent despite the ...
Janine Scholefield, Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Collen Masimirembwa   +5 more
wiley   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source