Results 41 to 50 of about 23,620 (204)
Frontiers in Toxicology, 2022 Genotoxicity testing relies on the detection of gene mutations and chromosome damage and has been used in the genetic safety assessment of drugs and chemicals for decades.
Julie K. Buick +17 more
doaj +1 more source
Systemic Inflammatory Response Syndrome from Nitrofurantoin: A Case Report [PDF]
, 2022 BACKGROUND: Nitrofurantoin is an antibiotic that is commonly used and preferred to treat lower urinary tract infections due to its relatively safe adverse effects profile. However, with the increased emphasis on antibiotic stewardship, it is important to
Brima, Wunnie +3 more
core +1 more source
, 1995 The reduction of nitrofurantoin by purified liver nitrofurantoin reductase was followed by the production of superoxide radicals, which were detected by the reduction of epinephrine. The conditions for the formation of superoxide radicals were optimized.
Güray, Nülüfer Tülün +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
Renal excretion of nitrofurantoin (Furadantin)
, 1959 Renal clearance of nitrofurantoin at various plasma levels was determined in the white rat. The clearance ratios (nitrofurantoin/inulin) exhibited a curvilinear relationship with the plasma level of the drug. The excretion of nitrofurantoin was found to
Esther G. Nohle +2 more
core +1 more source
Journal of Global Infectious Diseases, 2018 Background/Purpose: Most community-acquired urinary tract infections (UTIs) are usually treated empirically. The knowledge of antibiotic resistance patterns of the microorganisms causing UTI is essential for defining the empirical treatment.
Ilknur Erdem +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang +5 more
wiley +1 more source
Evaluation of the Effect of Nitrofurantoin Paste as an Intracanal Medicament on the Chemical Structure of Radicular Dentine [PDF]
, 2021 Objective: To investigate the effects of a new intracanal medicament (nitrofurantoin paste) on radicular dentin's chemical structure compared with modified triple antibiotic paste (MTAP).
Mewan S. Abdulrahman +5 more
core +2 more sources
Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane
Molecules, 2020 Due to the increasing use of antibiotics, measures are being taken to improve their removal from the natural environment. The support of biodegradation with natural surfactants that increase the bioavailability of impurities for microorganisms that ...
Monika Rojewska +3 more
doaj +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
Medicinal Research Reviews, EarlyView.ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source