Results 41 to 50 of about 16,580 (169)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Comprehensive assessment of nitrofurans for lower urinary tract infections [PDF]

Клиническая микробиология и антимикробная химиотерапия
Antimicrobial therapy is an essential part of treatment of urinary tract infections, often being the only etiological and pathogenetic component of it. At the same time, the rationality of choosing an antimicrobial depends both on the sensitivity of the ...
Kozlov R.S., Golub A.V.
doaj   +1 more source

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

Equine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald, J. P. Schramel, E. Haltmayer, N. M. Biermann   +3 more
wiley   +1 more source

Unraveling Mechanisms and Epidemic Characteristics of Nitrofurantoin Resistance in Uropathogenic Enterococcus faecium Clinical Isolates

Infection and Drug Resistance, 2021
Ying Zhang,1 Lingbo Wang,2 Cui Zhou,2 Yishuai Lin,1 Shixing Liu,2 Weiliang Zeng,1 Kaihang Yu,1 Tieli Zhou,2 Jianming Cao1 1Department of Medical Lab Science, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang ...
Zhang Y, Wang L, Zhou C, Lin Y, Liu S, Zeng W, Yu K, Zhou T, Cao J   +8 more
doaj  

Reversible interstitial lung disease with prolonged use of nitrofurantoin: Do the benefits outweigh the risks?

Lung India, 2013
We describe the case summary of a 70-year-old man diagnosed with interstitial lung disease due to prolonged nitrofurantoin therapy. Despite honeycombing confirmed by computed tomography of the thorax, symptoms and radiographic findings disappeared within
Akashdeep Singh, Parminder Singh, U S Sidhu   +2 more
doaj   +1 more source

Towards Prescribing Pathways for Oral Health Practitioners in Australia: Addressing Barriers to Patient‐Centered Care

Journal of Public Health Dentistry, EarlyView.
ABSTRACT Background Oral health practitioners (OHPs) provide essential preventive, periodontal, and restorative treatment within diverse settings in Australia. Despite their significant contribution to oral healthcare, regulatory restrictions prevent OHPs from independent prescription of medicines, limiting efficiency, continuity of care, and patient ...
W. Carlson‐Jones, T. Acret, A. Ayo, P. Westhoff, L. A. Church, M. Ratnaweera, B. Christian, J. Park, N. Stormon   +8 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

İDRAR YOLU ENFEKSİYONLARI İÇİN AMPİRİK ANTİBİYOTİK REÇETELEME UYGULAMALARI: TEK MERKEZLİ RETROSPEKTİFÇALIŞMA

Ankem Dergisi
Enfeksiyon hastalıklarında tedavi için rasyonel antibiyotik seçimi, antimikrobiyal direncin önlenmesinde önemli bir basamaktır. Bu çalışmada idrar kültürü yapılamayan bir ilçe merkezi hastanesinde idrar yolu enfeksiyonları (İYE) için ampirik antibiyotik ...
Mehmet Akif Gün, Önder Hancı
doaj   +1 more source

Consider Nitrofurantoin as a Cause of Lung Injury

European Journal of Case Reports in Internal Medicine, 2019
Nitrofurantoin-induced diffuse lung toxicity is well documented in the literature but is often misdiagnosed. We describe an 82-year-old female medicated with nitrofurantoin for the previous 2 years who was admitted for dyspnoea, dry cough and fatigue for
Paulo Almeida, Eduarda Seixas, Beatriz Pinheiro, Pedro Ferreira, Ana Araújo   +4 more
doaj   +1 more source

Pathogenicity and Antimicrobial‐Resistance Profiles of Escherichia coli Isolated From Faeces of Tibetan Pigs Reared Under Intensive Conditions

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Tibetan pig farms host diverse Escherichia coli strains that resist multiple antibiotics and carry important disease genes, such as astA. These traits jump easily between bacterial groups, marking intensive pig production as a key reservoir and signalling the need for integrated animal–human surveillance and more careful antibiotic use.
Runbo Luo, Lihong Zhang, Kexin Li, Yanan Zhong, Peng Shang, Suolang Sizhu, Md. F. Kulyar, Ruibing Cao   +7 more
wiley   +1 more source