Results 31 to 40 of about 40,209 (198)

Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]

, 2014
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core   +3 more sources

Divergent access to 5,6,7-perifused cycles

Nature Communications, 2023
Nitrogen-containing heterocycles are the key components in many pharmaceuticals and functional materials. In this study, we report a transition metal-catalyzed high-order reaction sequence for synthesizing a structurally unique N-center 5,6,7-perifused ...
Jingpeng Han, Yongjian Yang, Yingjian Gong, Xuan Tang, Yi Tian, Baosheng Li   +5 more
doaj   +1 more source

Photochemistry of N-(selenoalkyl)-phthalimides. Formation of N, Se-heterocyclic systems [PDF]

, 2015
A variety of N-(selenomethyl)alkyl-phthalimides (alkyl = -(CH2)n-; n = 2-5, 1a, b, d, e) and N-(selenobenzyl)propyl phthalimide (1c) were synthesized and their photochemistry was studied at λ = 300 nm.
Argüello, Juan Elias, Heredia, Adrián Alberto, Oksdath Mansilla, Gabriela, Peñeñory, Alicia Beatriz   +3 more
core   +1 more source

Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review [PDF]

BIO Web of Conferences
The synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their
Hamdi Abdeljalil, El Hammoudani Yahya, Ahari M’hamed, Amhamdi Hassan, Salhi Amin, El Youssfi Abdellah, El Houssien Akichouh, El Aatiaoui Abdelmalik   +7 more
doaj   +1 more source

Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides

Molecules, 2009
CuO/AB was found to be a simple and efficient catalyst for the N-arylation of a variety of nitrogen-containing heterocycles, giving the products in excellent yields.
Kang Hyun Park, Hyunjoon Song, Hyunju Kang, Haesik Yang, Ji Chan Park, A Young Kim, Hyun Ju Lee   +6 more
doaj   +1 more source

Catalytic asymmetric C-H insertion reactions of α-diazocarbonyl compounds [PDF]

, 2010
The purpose of this review is to provide an overview of the development of asymmetric catalysts for C-H insertion reactions over the past two decades, focusing on the application of these catalysts in the decomposition of α-diazocarbonyl compounds. Given
Ford, Alan, Maguire, Anita R., Slattery, Catherine N.   +2 more
core   +1 more source

Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts: Direct arylation of heterocycles

Beilstein Journal of Organic Chemistry, 2012
The use of [Pd(NHC)(cinnamyl)Cl] precatalysts in the direct arylation of heterocycles has been investigated. Among four different precatalysts, [Pd(SIPr)(cinnamyl)Cl] proved to be the most efficient promoter of the reaction.
Anthony R. Martin, Anthony Chartoire, Alexandra M. Z. Slawin, Steven P. Nolan   +3 more
doaj   +1 more source

1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Molecules, 2011
A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds.
Saeed Alshahrani, Assem Barakat, Yamin Siddiqui, Yahia Nasser Mabkhot, Abdullah Mohammed Al-Majid   +4 more
doaj   +1 more source

A sustainable thermochemical conversion of animal biomass to N-heterocycles

Journal of Leather Science and Engineering, 2023
The production of high-valued organonitrogen chemicals, especially N-heterocycles, requires artificial N2 fixation accompanied by the consumption of fossil resources.
Yang Tang, Xiao Xiao, Chaojun Zhang, Xiaoling Wang, Junling Guo, Xuepin Liao   +5 more
doaj   +1 more source

A Brief Review on the Synthesis of the N-CF₃ Motif in Heterocycles

Molecules, 2023
The trifluoromethyl group is widely recognized for its significant role in the fields of medicinal chemistry and material science due to its unique electronic and steric properties that can alter various physiochemical properties of the parent molecule ...
Zizhen Lei, Wenxu Chang, Hong Guo, Jiyao Feng, Zhenhua Zhang   +4 more
doaj   +1 more source