Results 21 to 30 of about 23,538 (226)

Synthesis of unprotected nitrogen-containing heterocycles via Aza Heck reactions

, 2022
Watson, Donald A.The main objective of this thesis is centered around the identification of novel amide electrophiles for the development of aza-Heck-type reactions.
Shuler, Scott Adam
core   +1 more source

Synthesis and Reactivity of 3H-1,2-dithiole-3-thiones

Molecules, 2021
3H-1,2-Dithiole-3-thiones are among the best studied classes of polysulfur-containing heterocycles due to the almost explosive recent interest in these compounds as sources of hydrogen sulfide as an endogenously produced gaseous signaling molecule.
Oleg A. Rakitin
doaj   +1 more source

Brønsted acid-enhanced copper-catalyzed atroposelective cycloisomerization to axially chiral arylquinolizones via dearomatization of pyridine

Nature Communications, 2022
Methods to assemble axially chiral biaryl molecules with nitrogen-containing heterocycles can have implications in ligand development for homogeneous catalysis. Here the authors report enantioselective syntheses of axially chiral arylquinolizones, via an
Xiao-Long Min, Xiu-Lian Zhang, Wenbin Yi, Ying He   +3 more
doaj   +1 more source

Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles

Molecules, 2022
Betulinic acid (BA) was used as starting building block to create a library of novel BA-derived compounds containing O- and N-heterocycles. Firstly, BA was converted into methyl betulonate (BoOMe), which was used as intermediate in the developed ...
Joana L. C. Sousa, Hélio M. T. Albuquerque, Armando J. D. Silvestre, Artur M. S. Silva   +3 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Proceedings, 2019
Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
Marole Maria Maluleka, Malose Jack Mphahlele   +1 more
doaj   +1 more source

Divergent access to 5,6,7-perifused cycles

Nature Communications, 2023
Nitrogen-containing heterocycles are the key components in many pharmaceuticals and functional materials. In this study, we report a transition metal-catalyzed high-order reaction sequence for synthesizing a structurally unique N-center 5,6,7-perifused ...
Jingpeng Han, Yongjian Yang, Yingjian Gong, Xuan Tang, Yi Tian, Baosheng Li   +5 more
doaj   +1 more source

Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review [PDF]

BIO Web of Conferences
The synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their
Hamdi Abdeljalil, El Hammoudani Yahya, Ahari M’hamed, Amhamdi Hassan, Salhi Amin, El Youssfi Abdellah, El Houssien Akichouh, El Aatiaoui Abdelmalik   +7 more
doaj   +1 more source

Domino Knoevenagel-cyclization reactions for the preparation of pyridine-containing condensed heterocycles

, 2022
In this thesis work, the goal was to synthesize chiral condensed O,N-heterocycles by the domino Knoevenagel-hetero Diels-Alder reaction from a 2-H-chromene derivative containing a pyridine-3-carbaldehyde moiety as a starting material. Eight new condensed
Kurtán, Tibor, Anjou, Tarek
core  

Synthesis of trifluoromethyl N , N -aminals from nitrogen containing heterocycles by using a plasma flow microreactor

, 2023
International audienceTrifluoromethyl N , N -aminals were synthesized from nitrogen containing heterocycles in a R 3 SiCF 3 solution, using an argon plasma in a flow microreactor.
Schio, Laurent, Ognier, Stephanie, Cossy, Janine, Tatoulian, Michael, Venier, Olivier, Abedelnour, Elias   +5 more
core   +1 more source

1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Molecules, 2011
A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds.
Saeed Alshahrani, Assem Barakat, Yamin Siddiqui, Yahia Nasser Mabkhot, Abdullah Mohammed Al-Majid   +4 more
doaj   +1 more source