Results 31 to 40 of about 40,586 (282)

Iridium-Catalyzed Silylation of Five-Membered Heteroarenes: High Sterically Derived Selectivity from a Pyridyl-Imidazoline Ligand. [PDF]

, 2020
The steric effects of substituents on five-membered rings are less pronounced than those on six-membered rings because of the difference in bond angles. Thus, the regioselectivities of reactions of five-membered heteroarenes that occur with selectivities
Hartwig, John F, Karmel, Caleb, Kharitonova, Elena V, Rubel, Camille Z   +3 more
core   +1 more source

Divergent access to 5,6,7-perifused cycles

Nature Communications, 2023
Nitrogen-containing heterocycles are the key components in many pharmaceuticals and functional materials. In this study, we report a transition metal-catalyzed high-order reaction sequence for synthesizing a structurally unique N-center 5,6,7-perifused ...
Jingpeng Han, Yongjian Yang, Yingjian Gong, Xuan Tang, Yi Tian, Baosheng Li   +5 more
doaj   +1 more source

Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]

, 2016
The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA, Croft, RA, Davis, OA, Doran, R, Morgan, KF   +4 more
core   +1 more source

Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review [PDF]

BIO Web of Conferences
The synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their
Hamdi Abdeljalil, El Hammoudani Yahya, Ahari M’hamed, Amhamdi Hassan, Salhi Amin, El Youssfi Abdellah, El Houssien Akichouh, El Aatiaoui Abdelmalik   +7 more
doaj   +1 more source

Silver and platinum-catalysed addition of O–H and N–H bonds to allenes [PDF]

, 2014
Transition-metal catalysed nucleophile addition to allenes is a very powerful tool for the synthesis of functionalised molecules containing heteroatoms, heterocycles in the intramolecular version, or allyl derivatives in the intermolecular version.
Munoz-Herranz, Maria
core   +1 more source

Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides

Molecules, 2009
CuO/AB was found to be a simple and efficient catalyst for the N-arylation of a variety of nitrogen-containing heterocycles, giving the products in excellent yields.
Kang Hyun Park, Hyunjoon Song, Hyunju Kang, Haesik Yang, Ji Chan Park, A Young Kim, Hyun Ju Lee   +6 more
doaj   +1 more source

Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts: Direct arylation of heterocycles

Beilstein Journal of Organic Chemistry, 2012
The use of [Pd(NHC)(cinnamyl)Cl] precatalysts in the direct arylation of heterocycles has been investigated. Among four different precatalysts, [Pd(SIPr)(cinnamyl)Cl] proved to be the most efficient promoter of the reaction.
Anthony R. Martin, Anthony Chartoire, Alexandra M. Z. Slawin, Steven P. Nolan   +3 more
doaj   +1 more source

1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Molecules, 2011
A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds.
Saeed Alshahrani, Assem Barakat, Yamin Siddiqui, Yahia Nasser Mabkhot, Abdullah Mohammed Al-Majid   +4 more
doaj   +1 more source

A Brief Review on the Synthesis of the N-CF₃ Motif in Heterocycles

Molecules, 2023
The trifluoromethyl group is widely recognized for its significant role in the fields of medicinal chemistry and material science due to its unique electronic and steric properties that can alter various physiochemical properties of the parent molecule ...
Zizhen Lei, Wenxu Chang, Hong Guo, Jiyao Feng, Zhenhua Zhang   +4 more
doaj   +1 more source

Renewable Microalgae-derived Nitrogen Doped Hydrothermal Carbons [PDF]

, 2012
Nitrogen-doped carbon materials are synthesized via an effective, sustainable, and green one-step route based on the hydrothermal carbonization of microalgae with high nitrogen content (ca. 11 wt %).
Falco, Camillo, Rothe, Regina, Sevilla Solís, Marta, Titirici, María-Magdalena, White, Robin J.   +4 more
core   +1 more source