Results 81 to 90 of about 4,736,631 (400)

The Effects of Initial Abundances on Nitrogen in Protoplanetary Disks

, 2014
The dominant form of nitrogen provided to most solar system bodies is currently unknown, though available measurements show that the detected nitrogen in solar system rocks and ices is depleted with respect to solar abundances and the interstellar medium.
Bergin, Edwin A., Schwarz, Kamber R.
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Environmental Impact Assessment for Animal Waste, Organic and Synthetic Fertilizers

Nitrogen, 2023
The use of fertilizers is of the utmost importance for food security on a global scale. However, fertilizer production and overuse may yield environmental issues.
Vassilis D. Litskas
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Optimization and Dynamic Adjustment of Tandem Columns for Separating an Ethylbenzene–Styrene Mixture Using a Multi-Objective Particle Swarm Algorithm

Separations
This study focuses on optimizing two tandem columns to separate ethylbenzene and styrene. A steady-state model is developed to minimize total energy consumption (TEC) and total annualized cost (TAC) by optimizing the reflux flow rates.
Guangsheng Jiang, Yibo She, Zhongwen Song, Liwen Zhao, Guilian Liu   +4 more
doaj   +1 more source

Extra contribution to the crystal stability of insensitive explosive TATB: The cooperativity of intermolecular interactions

Defence Technology, 2023
An in-depth analysis on the cooperativity of intermolecular interactions including hydrogen bonding and π-π stacking in 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) crystal was studied.
Zhi-xiang Zhang, Yi-tao Si, Tao Yu, Wei-peng Lai, Yi-ding Ma, Mao-chang Liu, Ying-zhe Liu, Bo-zhou Wang   +7 more
doaj  

Isoenzymatic Pattern of Hydrogen Sulfide (H₂S)-Generating L-Cysteine Desulfhydrase (LCD) in Arabidopsis thaliana Seedlings: Effect of Nitric Oxide (NO) and H₂S

Nitrogen, 2023
In higher plants, hydrogen sulfide (H2S) is a recognized signaling molecule that performs multiple regulatory functions. The enzyme L-cysteine desulfhydrase (LCD) catalyzes the conversion of L-cysteine (L-Cys) to pyruvate and ammonium with the ...
Jorge De La O-Sánchez, María A. Muñoz-Vargas, José M. Palma, Francisco J. Corpas   +3 more
doaj   +1 more source

Niche differentiation in nitrogen metabolism among methanotrophs within an operational taxonomic unit [PDF]

, 2014
Background: The currently accepted thesis on nitrogenous fertilizer additions on methane oxidation activity assumes niche partitioning among methanotrophic species, with activity responses to changes in nitrogen content being dependent on the in situ ...
Boon, Nico, De Vos, Paul, Heylen, Kim, Hoefman, Sven, van der Ha, David, Vandamme, Peter   +5 more
core   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The Role of Threonine Deaminase/Dehydratase in Winter Dormancy in Sweet Cherry Buds

Nitrogen, 2023
The determination of the endodormancy release and the beginning of ontogenetic development is a challenge, because these are non-observable stages. Changes in protein activity are important aspects of signal transduction. The conversion of threonine to 2-
Klaus-Peter Götz, Chibueze Ene, Joerg Fettke, Frank-M. Chmielewski   +3 more
doaj   +1 more source