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Nitrogen-fused Heterocycles: Empowering Anticancer Drug Discovery.

Medicinal chemistry
The worldwide impact of cancer is further compounded by the constraints of current anticancer medications, which frequently exhibit a lack of selectivity, raise safety apprehensions, result in significant adverse reactions, and encounter resistance ...
Tanya Biswas   +4 more
semanticscholar   +1 more source

Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions.

Organic and biomolecular chemistry, 2019
The prevalence of nitrogen containing heterocycles in natural products and pharmaceuticals is a doubtless fact. In this review, recent applications of a stereoselective aza-Michael reaction as an efficient tool for the asymmetric synthesis of naturally ...
M. G. Vinogradov   +2 more
semanticscholar   +1 more source

Straightforward Construction and Functionalizations of Nitrogen‐Containing Heterocycles Through Migratory Insertion of Metal‐Carbenes/Nitrenes

The chemical record, 2021
Nitrogen‐containing heterocycles are widely found in various biologically active substrates, pharmaceuticals, natural products and organic materials.
S. Bera, Aniruddha Biswas, R. Samanta
semanticscholar   +1 more source

Recent advances in biocatalysis of nitrogen-containing heterocycles.

Biotechnology Advances, 2021
Nitrogen-containing heterocycles (N-heterocycles) are ubiquitous in both organisms and pharmaceutical products. Biocatalysts are providing green approaches for synthesizing various N-heterocycles under mild reaction conditions. This review summarizes the
Jing Feng   +3 more
semanticscholar   +1 more source

Review. Inverse coordination. Organic nitrogen heterocycles as coordination centers. A survey of molecular topologies and systematization. Part 2. Six-membered rings

Journal of coordination chemistry, 2019
The review is a follow-up of a previous article (I. Haiduc, J. Coord. Chem. (2019). DOI: 10.1080/00958972.2019.1641702), which introduced structures with five-membered nitrogen heterocycles as inverse coordination centers. This review presents a panorama
I. Haiduc
semanticscholar   +1 more source

Ring opening reactions of nitrogen heterocycles

Russian Chemical Reviews, 2019
Published data on ring opening reactions of nitrogen-containing cyclic compounds resulting in various acyclic products are integrated and systematized.
A. Smolobochkin   +4 more
semanticscholar   +1 more source

Photooxygenations of nitrogen heterocycles

Chemical Reviews, 1979
This review attempts to catalogue some of the reported photooxygenated reactions of different nitrogen heterocycles. Attention has been focused on the different types of products formed in these reactions and some of the suggested pathways for their formation. Although detailed studies on the mechanism of photooxygenation reactions have been performed,
M. V. George, V. Bhat
openaire   +1 more source

Nitrogen-Rich Heterocycles

2007
Many advantages accrue from nitrogen-rich heterocyclic compounds compared to traditional molecular energetic compounds. Utilization of heterocyclic nitrogen-containing cations and anions in energetic salts gives rise to lower vapor pressures, higher heats of formation and higher densities. Additionally, smaller amounts of hydrogen and carbon contribute
Rajendra P. Singh   +3 more
openaire   +1 more source

Nitrogen Heterocycles: Porphyrins

Photoorganocatalysis in Organic Synthesis, 2019
Hermenegildo García   +1 more
openaire   +2 more sources

Synthesis of Five-Membered Iodine-Nitrogen Heterocycles from Benzimidazole-Based Iodonium Salts.

Journal of Organic Chemistry, 2018
Pseudocyclic 2-benzimidazolyl-substituted diaryliodonium salts were obtained by the reaction of the corresponding [hydroxy(tosyloxy)iodo]arenes with arenes in the presence of trifluoromethanesulfonic acid.
Yulia A Vlasenko   +6 more
semanticscholar   +1 more source

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