Results 171 to 180 of about 871,548 (248)

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

Hierarchical Membrane for Photoelectrostatically Gated Monovalent‐Divalent Ion Separation

open access: yesAngewandte Chemie International Edition, EarlyView.
We report a hierarchical poly(ionic liquid)–carbon nitride membrane supported on anodic alumina for efficient monovalent/divalent ion separation. Confined nanochannels and tailored interfacial ion interactions enable exceptional K+/Mg2+ ( > 500) and Li+/Mg2+ ( > 200) selectivities, offering a promising strategy for advanced aqueous ion separations ...
Enis Oğuzhan Eren   +3 more
wiley   +1 more source

Granular Bed Filtration of Coal Pyrolysis Gas: Effects of Media Reactivity on Dust Removal and Products

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Granular bed filtration is a promising technology for removing dust from high‐temperature coal pyrolysis gas. In this work, the reactivity of coal pyrolysis products over ceramsite, char, ultrastable Y‐type (USY) zeolite, and quartz particles was compared.
Shuaiqiang Yang   +4 more
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

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